| Ssta Services Ltd | Information & communication | 2025 |
| Sswp Group Limited | Administrative & support | 2024 |
| ST & T Limited | Health & social care | 2017 |
| ST Alkmunds Way Management Company Limited | Households | 1992 |
| ST Andrew's Park (Dice) Estate Management Company Limited | Households | 2019 |
| ST Andrew's Park (Phase 4 Uxbridge) Estate Management Company Limited | Households | 2017 |
| ST Andrews Advisory Limited | Professional & scientific | 2024 |
| ST Andrews Pre-School (Derby) Community Interest Company | Education | 2016 |
| ST Barber Derby Ltd | Other services | 2025 |
| ST Edmunds Preschool Community Interest Company | Education | 2015 |
| ST Francis Drive Management (Ruddington) Limited | Households | 2017 |
| ST Georges (Derby) Management Company Limited | Households | 2003 |
| ST Helens House Derby Limited | Real estate | 2023 |
| ST Ignatius Holdings Ltd | Real estate | 2021 |
| ST James Construction & Property Limited | Construction | 2018 |
| ST James Hair Team Limited | Other services | 2003 |
| ST James Inns Ltd | Hospitality | 2017 |
| ST James Street (Derby) Limited | Real estate | 2023 |
| ST James' Centre (Derby) | Health & social care | 1993 |
| ST John's School (Belper) Management Company Limited | Households | 2004 |
| ST Marght Ltd | Administrative & support | 2026 |
| ST Nicholas Place Management Company Limited | Hospitality | 1999 |
| ST Paul's Quality Health Limited | Health & social care | 2012 |
| ST Peter's Holdings Limited | Real estate | 2025 |
| ST Ralph Sherwin Catholic Multi Academy Trust | Education | 2012 |
| ST Thomas Carpets & Furniture Ltd | Wholesale & retail | 2007 |
| ST Werburgh’S Derby | Other services | 2017 |
| ST. Ives Nursery Limited | Education | 2003 |
| ST. Leonards Stafford Estate Management Company Limited | Households | 2020 |
| ST. Modwen Developments (Longbridge) Limited | Real estate | 1994 |
| ST. Modwen Homes (Lease-Holding Entity) Limited | Real estate | 2024 |
| ST. Modwen Homes (Wades) Limited | Real estate | 2023 |
| ST. Modwen Homes Limited | Real estate | 2014 |
| ST. Peters Quarter Derby Limited | Administrative & support | 2009 |
| ST46 Ltd | Construction | 2026 |
| Stable Ales Ltd | Wholesale & retail | 2020 |
| Stable Communications Ltd | Information & communication | 2013 |
| Stable Property Group Ltd | Real estate | 2025 |
| Stac Solutions Ltd | Information & communication | 2018 |
| Stac Works Limited | Information & communication | 2010 |
| Stacey Dexter Beauty Ltd | Administrative & support | 2025 |
| Stacey Dexter Group Ltd | Financial services | 2025 |
| Stacey Dexter Hairdressing Ltd | Other services | 2015 |
| Stack Estate Derbyshire Ltd | Real estate | 2021 |
| Stack Homes Limited | Real estate | 2012 |
| Stackware Ltd | Information & communication | 2024 |
| Staco Ltd | Construction | 2013 |
| Stade Developments (Hastings) Limited | Professional & scientific | 1971 |
| Stadia Media Group Limited | Information & communication | 2026 |
| Stadium Court Management Company Limited | Real estate | 2001 |
| Staff Roster Solutions Limited | Information & communication | 2010 |
| Stafford (Derby) Management Company Limited | Real estate | 2015 |
| Staffs Concrete Limited | Extraterritorial | 2004 |
| Stagoak Limited | Real estate | 2025 |
| Stainsby House Management Ltd | Households | 2012 |
| Stalwart Security Limited | Financial services | 1990 |
| Stalwart Security Services Limited | Extraterritorial | 1984 |
| Stamps Holdings Limited | Manufacturing | 2018 |
| Stan & Daughters Ltd | Other services | 2025 |
| Standard Plumbing Heating Solutions Ltd | Construction | 2024 |
| Standart Limited | Construction | 2014 |
| Stanford Maxwell Limited | Real estate | 2022 |
| Stanford Village Farm Management Company Limited | Households | 2010 |
| Stanley Dime Ltd | Real estate | 2016 |
| Stannards' Restaurant Limited | Hospitality | 2012 |
| Stanton Developments (Derby) Limited | Construction | 2015 |
| Stanton Energy Ltd | Energy | 2018 |
| Stanton Environmental Limited | Water & waste | 2015 |
| Stanyon & Holmes Limited | Extraterritorial | 1959 |
| Stapenhill Tandoori Ltd | Hospitality | 2021 |
| Stapleford Roofing Limited | Construction | 2023 |
| Star Bedrooms Limited | Wholesale & retail | 2014 |
| Star BEE Limited | Real estate | 2023 |
| Star Bright Facility Services Ltd | Administrative & support | 2017 |
| Star Bright Living Limited | Health & social care | 2021 |
| Star Building Limited | Real estate | 2023 |
| Star Cutz Limited | Other services | 2015 |
| Star Furnishings Ltd | Transport & logistics | 2006 |
| Star Global Engineering Ltd | Professional & scientific | 2020 |
| Star Gold Mutilinks Limited | Wholesale & retail | 2025 |
| Star M&E Solutions Ltd | Construction | 2001 |
| Star Metal Works Midland Ltd | Manufacturing | 2024 |
| Star Micronics GB Limited | Wholesale & retail | 1991 |
| Star Signs (Derby) Limited | Manufacturing | 2008 |
| Starberry Limited | Professional & scientific | 2001 |
| Starboyapparel Ltd | Wholesale & retail | 2024 |
| Starburst Consulting Ltd | Professional & scientific | 2006 |
| Starcom Technologies Limited | Information & communication | 1988 |
| Starcutz Village Limited | Other services | 2019 |
| Stargate Assets Ltd | Real estate | 2025 |
| Stargazer Media Ltd. | Professional & scientific | 2020 |
| Stargazer Retreats Ltd | Hospitality | 2023 |
| Starglider.Consulting Ltd | Information & communication | 2017 |
| Starkey Building Consultancy Ltd | Professional & scientific | 2018 |
| Starky & SON Crane Services Limited | Construction | 2010 |
| Starlet Lettings Ltd | Real estate | 2023 |
| Starlight Engineering Solutions Ltd | Professional & scientific | 2015 |
| Starstrat Limited | Professional & scientific | 2024 |
| Start Right Motorsport Ltd | Information & communication | 2026 |
| Start Small | Health & social care | 2012 |