| Mead Engineering Ltd | Manufacturing | 2025 |
| Meadcroft Services Limited | Administrative & support | 2022 |
| Meadow END Limited | Health & social care | 2005 |
| Meadow Farm Hilton Ltd | Manufacturing | 2024 |
| Meadow Group Services Limited | Financial services | 1987 |
| Meadow Haven House Limited | Health & social care | 2026 |
| Meadow Lane Services Limited | Real estate | 2019 |
| Meadow Realty Limited | Financial services | 2023 |
| Meadow View Pharma Consultancy Ltd | Other services | 2024 |
| Meadowbrook Chase Management Company Ltd | Households | 2025 |
| Meadows View (Bottesford) Management Company Limited | Households | 2019 |
| Meadowview Homes Ltd | Construction | 2013 |
| Meadvale Holdings Limited | Financial services | 2020 |
| Meakin Joinery Limited | Construction | 2026 |
| Meal to Go Express Ltd | Hospitality | 2025 |
| Mealprep Ltd | Manufacturing | 2023 |
| Meant to BE Homes Limited | Construction | 2022 |
| MEC Technical Ltd | Manufacturing | 2023 |
| Meclones Global Ltd | Administrative & support | 2026 |
| Mectek Mechanical Services Limited | Manufacturing | 1999 |
| MED Food ARK Ltd | Wholesale & retail | 2024 |
| Medal Magic Limited | Wholesale & retail | 2019 |
| Medartis Limited | Wholesale & retail | 2002 |
| Medarzt Ltd | Health & social care | 2023 |
| Meddo Ltd | Financial services | 2024 |
| Medhitech Ltd | Information & communication | 2022 |
| Media Action for Child Safety and Information Literacy CIC | Professional & scientific | 2026 |
| Mediasphere Limited | Professional & scientific | 1999 |
| Mediaworks Trust | Information & communication | 2003 |
| Medibord Limited | Manufacturing | 2009 |
| Medical Fabrica Limited | Other services | 2025 |
| Medical Frontliners Ltd | Professional & scientific | 2021 |
| Medical Reporting Ltd | Health & social care | 2015 |
| Medicare Bureau Limited | Other services | 2021 |
| Medifinancial Limited | Professional & scientific | 2011 |
| Medihealthcare (UK) Limited | Wholesale & retail | 2008 |
| Medilon Medical Services Ltd | Health & social care | 2022 |
| Mediq Healthcare UK Limited | Wholesale & retail | 1899 |
| Mediq Holding UK Limited | Other services | 2020 |
| Mediscan Staffing Limited | Administrative & support | 2022 |
| Mediterranean Sea Ltd | Wholesale & retail | 2009 |
| Mednxt Ltd | Health & social care | 2010 |
| Mednxt Properties Ltd | Real estate | 2026 |
| Medorva Limited | Wholesale & retail | 2023 |
| Meds Lettings Ltd | Real estate | 2020 |
| Medstead Road Management Company Limited | Households | 2016 |
| Medstrom EBT Ltd | Professional & scientific | 2019 |
| Medtech Connect Ltd | Professional & scientific | 2019 |
| MEE Bookkeeping Ltd | Professional & scientific | 2018 |
| Meei Holdings Ltd | Professional & scientific | 2024 |
| Meena Bazaar Limited | Wholesale & retail | 2026 |
| Meer Property Group Limited | Real estate | 2023 |
| Meerkat Comms Limited | Information & communication | 2003 |
| MEG Derby Limited | Manufacturing | 2018 |
| Meg's Delight Catering Services Limited | Hospitality | 2023 |
| Mega Play Ltd | Arts & recreation | 2025 |
| Megamaxtradersuk Ltd | Wholesale & retail | 2026 |
| Megatech IT Services Limited | Information & communication | 2017 |
| Megatech Traders Limited | Wholesale & retail | 2025 |
| Megtrans Direct Ltd | Transport & logistics | 2023 |
| MEH Interiors Limited | Professional & scientific | 2020 |
| Mehan Property Group Ltd | Real estate | 2025 |
| Mehar-Ali Foods Ltd | Hospitality | 2024 |
| Mehboob UR Rahman Limited | Wholesale & retail | 2024 |
| Mehfooz Haulage Limited | Administrative & support | 2017 |
| Mehrab Limited | Hospitality | 2024 |
| Mehreen Transport Services Limited | Transport & logistics | 2025 |
| Meilė Ltd | Wholesale & retail | 2023 |
| Melbourne Assembly Rooms Limited | Other services | 2011 |
| Melbourne Auditing Limited | Professional & scientific | 2014 |
| Melbourne Barns Management Company Limited | Extraterritorial | 1989 |
| Melbourne Business Court Management Company Limited | Real estate | 2003 |
| Melbourne Business Services Ltd | Professional & scientific | 2023 |
| Melbourne Developments Limited | Construction | 1989 |
| Melbourne Dynamo Football Club Ltd | Arts & recreation | 2026 |
| Melbourne Electrical Services Limited | Construction | 2009 |
| Melbourne Fishbar Limited | Hospitality | 2010 |
| Melbourne Garages Limited | Wholesale & retail | 2009 |
| Melbourne GAS, Plumbing & Heating Limited | Construction | 2014 |
| Melbourne House Derby Limited | Real estate | 2025 |
| Melbourne House Limited | Construction | 1987 |
| Melbourne KIT Shop Ltd | Wholesale & retail | 2024 |
| Melbourne Metals Limited | Wholesale & retail | 1980 |
| Melbourne Plumbing & Bathrooms Limited | Construction | 2014 |
| Melbourne Print Limited | Administrative & support | 2011 |
| Melbourne Property Services and Developments Limited | Construction | 2023 |
| Melbourne RFC Ltd | Arts & recreation | 2008 |
| Melbourne Sweets and Treats Limited | Wholesale & retail | 2010 |
| Melbourne View Hotel and Events Limited | Hospitality | 2017 |
| Melick Drive Apartments Management Company Limited | Households | 2024 |
| Melius Curo Limited | Professional & scientific | 2016 |
| Mellison Property Group Limited | Real estate | 2024 |
| Mellon Property Investment Derby Ltd | Real estate | 2024 |
| Mellor Reid Architects Limited | Professional & scientific | 2024 |
| Mellors Barbers Limited | Other services | 2025 |
| Mellowcare Ltd | Health & social care | 2017 |
| Melody Estates Ltd | Real estate | 2024 |
| Melody’S Baby Boutique Ltd | Wholesale & retail | 2024 |
| Melsthetics Limited | Health & social care | 2025 |
| Melton Place (Derby) Management Company Limited | Households | 2005 |