| Clwydian Films Limited | Information & communication | 2014 |
| Clwydian Walking Holidays Ltd. | Administrative & support | 2008 |
| Colet Care Ltd | Financial services | 2016 |
| Commercial Rigging Services Ltd | Information & communication | 2004 |
| Complete Information Technology Solutions Limited | Information & communication | 2004 |
| Container Sales Centre Limited | Wholesale & retail | 2009 |
| Conwy Music Co-Operative Ltd | Education | 2025 |
| Cook Street Consulting Ltd | Professional & scientific | 2024 |
| Cooke Milking Equipment Ltd | Manufacturing | 2012 |
| Core Focus Business Solutions Limited | Administrative & support | 2026 |
| Coriander Denbigh Ltd | Hospitality | 2022 |
| Creating Conscious Futures Ltd | Health & social care | 2024 |
| Crest Trading Stores Limited | Wholesale & retail | 2020 |
| Croenllwm CYF | Agriculture & fishing | 2015 |
| Ctcs Ltd | Other services | 2002 |
| Cummings Electrical Ltd | Administrative & support | 2017 |
| Cvam Asset Auctions Limited | Extraterritorial | 2008 |
| Cvam Holdings Ltd | Financial services | 2015 |
| Cvam Limited | Wholesale & retail | 2008 |
| Cvam Rental Limited | Professional & scientific | 2008 |
| Cyfathrebu Ceidiog Communication CYF | Professional & scientific | 2004 |
| Cyfrifon IAN Roberts Limited | Professional & scientific | 2005 |
| Cymdeithas Cadwraeth Llanrhaeadr YC Preservation Society | Arts & recreation | 2012 |
| Cynnig Glyndwr CYF | Health & social care | 1994 |
| D & J Electronics Ltd | Manufacturing | 2026 |
| D Rothwell Ltd | Professional & scientific | 2022 |
| D V Containers Limited | Administrative & support | 2013 |
| D.F.And M.Welsh Baptist Corporation | Other services | 1954 |
| Daniel Morris Butchers Ltd | Wholesale & retail | 2018 |
| Daniel T Jones CYF | Construction | 2019 |
| Dankol Limited | Wholesale & retail | 2013 |
| Daphne's Welsh Lamb Limited | Agriculture & fishing | 2019 |
| Data Vision Consultancy Ltd | Information & communication | 2024 |
| Davcol Limited | Financial services | 2021 |
| Dave Jones A.I.C. Technician Limited | Administrative & support | 2010 |
| David Lloyd Accountancy Services Ltd | Professional & scientific | 2012 |
| David O'Donnell Services Ltd | Transport & logistics | 2018 |
| Davies Brothers NW Limited | Administrative & support | 2021 |
| Davies Offshore Fibre Ltd | Construction | 2026 |
| Denbigh Building Plastics Ltd | Other services | 2004 |
| Denbigh Hand Car Wash Ltd | Wholesale & retail | 2025 |
| Denbigh Masonic Buildings Limited | Other services | 1985 |
| Denbigh Men's Shed Limited | Health & social care | 2015 |
| Denbigh Nail Ltd | Other services | 2021 |
| Denbigh Timber Products Limited | Manufacturing | 2002 |
| Denbighshire Leisure Limited | Arts & recreation | 2019 |
| Derwen DEG Properties Limited | Households | 2026 |
| Design Build London Ltd | Construction | 2025 |
| Devine Club Class Ltd | Arts & recreation | 2017 |
| Dewi Roberts CYF | Energy | 2014 |
| DLL Events Ltd | Arts & recreation | 2025 |
| DLL F&B Ltd | Hospitality | 2025 |
| DLL Group Ltd | Hospitality | 2024 |
| DLL Leisure Ltd | Arts & recreation | 2025 |
| DMF Consult Ltd | Professional & scientific | 2020 |
| Dolwen Riverside Camping Limited | Hospitality | 2023 |
| Dragon in the Hills CIC | Health & social care | 2023 |
| Dragonbroome Ltd | Health & social care | 2023 |
| Draig AUR Ltd | Financial services | 2026 |
| Dream Safety Training and Consulting Ltd | Education | 2025 |
| Drivebm Ltd | Professional & scientific | 2026 |
| Driving HGV Services Ltd | Transport & logistics | 2022 |
| DSG Real Estate Limited | Information & communication | 2021 |
| DTP Haulage Ltd | Transport & logistics | 2015 |
| DTP Holdings Ltd | Financial services | 2018 |
| DYD Network Solutions Limited | Information & communication | 2022 |
| Dylan Roberts CYF | Manufacturing | 2012 |
| E G Morris Electrical Limited | Construction | 2013 |
| E Jones & SON Ltd | Construction | 2016 |
| E-Comas Distribution Ltd | Wholesale & retail | 2025 |
| E.M.Clarke Ltd | Professional & scientific | 2024 |
| Ecocore Research Ltd | Professional & scientific | 2025 |
| Ecocore Technolgies Ltd | Manufacturing | 2025 |
| Ecocrib Ltd | Administrative & support | 2010 |
| EDL Containers Ltd | Wholesale & retail | 2026 |
| Edwards Contractors NW Ltd | Construction | 2025 |
| Effeithiol CYF | Administrative & support | 2025 |
| Eithin Limited | Real estate | 2023 |
| EJE Promotions Ltd | Information & communication | 2024 |
| EJS Water Services Limited | Construction | 1997 |
| EL Herrero Roost Control LLP | | 2021 |
| Elevate Pitch Decks Ltd | Information & communication | 2023 |
| Elite Nail Services Ltd | Other services | 2015 |
| Ellis Sporting Ltd | Agriculture & fishing | 2022 |
| Envirolyte UK Limited | Other services | 2007 |
| ERH Accountancy Limited | Professional & scientific | 2012 |
| Evans Gwyndy CYF | Agriculture & fishing | 2017 |
| Evans Kilford CYF | Agriculture & fishing | 2022 |
| Event Bird Ltd | Other services | 2011 |
| Everything 123 Ltd | Professional & scientific | 2021 |
| Extreme Cleanz Ltd | Administrative & support | 2022 |
| F. F. Wholesale Ltd | Wholesale & retail | 2013 |
| Ffrindiau Bach CIC | Health & social care | 2023 |
| Ffynnon Engineering Limited | Wholesale & retail | 2004 |
| Finest Planner LLP | | 2026 |
| Fishing Education & Wellbeing Ltd | Education | 2025 |
| Flam Y Ddraig Catering Ltd. | Hospitality | 2025 |
| Flat Rate Training Ltd | Information & communication | 2019 |
| Flintshire Furniture Limited | Wholesale & retail | 2010 |
| Flourish Marketing NW Ltd | Administrative & support | 2025 |