| Croix Deaf Intermediary Ltd | Professional & scientific | 2019 |
| Cross Environmental Services (CES) Ltd | Professional & scientific | 2023 |
| Crown Brands Limited | Professional & scientific | 2008 |
| Crown Care Homes Limited | Health & social care | 1987 |
| Crown Ever Ltd | Wholesale & retail | 2024 |
| Crown Paints Group Limited | Professional & scientific | 2008 |
| Crown Paints Holdings Limited | Professional & scientific | 2008 |
| Crown Paints Limited | Manufacturing | 2008 |
| CRP Haulage Limited | Transport & logistics | 2025 |
| Crunchy Plus Ltd | Hospitality | 2010 |
| CSC Auto Service Ltd | Wholesale & retail | 2025 |
| CUR8PHARM Limited | Wholesale & retail | 2024 |
| CVS (NW) Ltd | Wholesale & retail | 2019 |
| Cypexsoft Ltd | Information & communication | 2023 |
| D & B Equipment Ltd. | Wholesale & retail | 2003 |
| D & E Groundworks Ltd | Construction | 2015 |
| D & P Leigh Holdings Limited | Real estate | 2026 |
| D & V Holden Limited | Professional & scientific | 2015 |
| D R and J Searle Limited | Health & social care | 2013 |
| D Rose Limited | Professional & scientific | 2013 |
| D W Roberts Optical Limited | Wholesale & retail | 2021 |
| D Whittaker & Co Limited | Wholesale & retail | 2008 |
| D&A Build Ltd | Construction | 2023 |
| D.H.J. Weisters Limited | Manufacturing | 1984 |
| DA Service Design Ltd | Professional & scientific | 2024 |
| Daisy Luxe Limited | Wholesale & retail | 2023 |
| Dalecuts Limited | Manufacturing | 1999 |
| Daley Links Ltd | Professional & scientific | 2025 |
| Danny Lomax Logistics Ltd | Transport & logistics | 2025 |
| Darreners Upholstery Ltd | Other services | 2023 |
| Darryl Neal Property Development Ltd | Construction | 2026 |
| Dart Zone Ltd | Arts & recreation | 2017 |
| Darwen Accident Repair Centre Limited | Wholesale & retail | 2009 |
| Darwen Acupuncture Clinic Ltd | Health & social care | 2022 |
| Darwen Asset Management Limited | Administrative & support | 2025 |
| Darwen Barbers Ltd | Other services | 2017 |
| Darwen Car Sales Ltd | Wholesale & retail | 2025 |
| Darwen Carwash Ltd | Administrative & support | 2021 |
| Darwen Central Building Limited Liability Partnership | | 2006 |
| Darwen Community Helpers CIC | Administrative & support | 2022 |
| Darwen Cycle Repairs Ltd | Manufacturing | 2019 |
| Darwen Drywall and Plastering Ltd | Construction | 2021 |
| Darwen Express Ltd | Wholesale & retail | 2016 |
| Darwen FC | Arts & recreation | 2005 |
| Darwen Heritage Kitchen Limited | Hospitality | 2026 |
| Darwen Management Services Limited | Wholesale & retail | 2001 |
| Darwen MOT Centre Limited | Wholesale & retail | 2022 |
| Darwen Pallets Ltd | Wholesale & retail | 2018 |
| Darwen Pizza & Grill Ltd | Hospitality | 2022 |
| Darwen Pizza House Limited | Hospitality | 2023 |
| Darwen PUB Co Ltd | Hospitality | 2025 |
| Darwen Recruitment Ltd | Administrative & support | 2026 |
| Darwen Services Ltd | Wholesale & retail | 2026 |
| Darwen Subscription Bowling Club Company,Limited | Arts & recreation | 1897 |
| Darwen Trade Limited | Other services | 2023 |
| Darwen Travel Services Ltd | Administrative & support | 2021 |
| Darwen Valeting Centre Ltd | Other services | 2020 |
| Darwen Valley Community Centre Management Board Limited | Education | 2020 |
| Darwen Van Courier Ltd | Transport & logistics | 2026 |
| Darwenn Ltd | Transport & logistics | 2015 |
| Datenight Clothing Limited | Wholesale & retail | 2021 |
| Dato Property Ltd | Real estate | 2022 |
| Datsa Limited | Wholesale & retail | 2002 |
| Dauphin Humandesign UK Limited | Wholesale & retail | 1987 |
| David Burghardt Vision Care Limited | Wholesale & retail | 2013 |
| David Faulder Limited | Wholesale & retail | 2026 |
| David Hillel Optical Limited | Wholesale & retail | 2024 |
| David Inman (Opticians) Limited | Wholesale & retail | 1976 |
| David Inman Opticians (Broomhill) Limited | Wholesale & retail | 2004 |
| David Kear Optical Limited | Wholesale & retail | 2024 |
| David Mcwilliams Limited | Health & social care | 2005 |
| Davis (MH) Limited | Health & social care | 2010 |
| Davis Optometrists Ltd | Wholesale & retail | 2014 |
| Dawkins & Lodge Limited | Health & social care | 2009 |
| Dawn Pave Ltd | Construction | 2021 |
| Dawndrives Ltd | Construction | 2021 |
| Dawson's Kitchens and Bars Ltd | Hospitality | 2020 |
| Daybell & Choo (Eyecare) LLP | | 2014 |
| Daybell & Choo Limited | Wholesale & retail | 2021 |
| DB Electrical Services (NW) Ltd | Construction | 2020 |
| DB Hughes Optical Limited | Wholesale & retail | 2021 |
| DC2 Holdings Ltd | Financial services | 2023 |
| Ddunkley Holdings Ltd | Real estate | 2025 |
| Debsline.Co Ltd | Wholesale & retail | 2026 |
| Debt Advice Foundation | Financial services | 2012 |
| Decelec (NW) Ltd | Construction | 2022 |
| Declan James Properties Ltd | Real estate | 2022 |
| Deen Industry Ltd | Wholesale & retail | 2024 |
| Deen Pharmacy Limited | Wholesale & retail | 1985 |
| Deks Investments Ltd | Real estate | 2022 |
| Delgreco Homes Limited | Extraterritorial | 2003 |
| Dellboys Discounts Ltd | Wholesale & retail | 2025 |
| Delph Sailing Club,Limited | Arts & recreation | 1966 |
| DENTIST-2U Limited | Health & social care | 2025 |
| Denton Stove Centre Limited | Wholesale & retail | 2025 |
| Desserts at Midnight Ltd | Hospitality | 2026 |
| Devdos Limited | Real estate | 2020 |
| Developer Lions Limited | Real estate | 2025 |
| Dewitt's Ltd | Construction | 2024 |
| Dfab Consulting Ltd | Professional & scientific | 2025 |