| Stafford Optical Ltd | Wholesale & retail | 2020 |
| Staircase Financial Ltd | Financial services | 2026 |
| Stanciu Cosmetics Ltd | Wholesale & retail | 2025 |
| Stanley Groundworks & Roofing Ltd | Construction | 2025 |
| Staples Optical Limited | Wholesale & retail | 2019 |
| Starshell Energy Limited | Real estate | 2010 |
| Station Tyres Limited | Wholesale & retail | 2022 |
| Stay LOW Ltd | Information & communication | 2017 |
| Stebert Trinity Global Resources Ltd | Real estate | 2022 |
| Stems by Sarah Ltd | Wholesale & retail | 2022 |
| Stephen Evans Optical Limited | Wholesale & retail | 2019 |
| Stephen Wilcox Optometrists Limited | Health & social care | 2005 |
| Stephen Wood Training Services Ltd | Education | 2011 |
| Stephens Opticians Limited | Wholesale & retail | 1997 |
| Steve Mayer Optical Limited | Wholesale & retail | 2021 |
| STL Technology Solutions Holdings Limited | Information & communication | 2010 |
| Stokers Optical Ltd | Health & social care | 2014 |
| Storage Bidder Limited | Wholesale & retail | 2017 |
| Storyfolk Limited | Information & communication | 2015 |
| Strickland-Clarke Holdings Limited | Real estate | 2022 |
| Striding Edge Management Co Ltd | Extraterritorial | 2023 |
| Stsms Limited | Information & communication | 2025 |
| Stulee Window Cleaning Ltd | Administrative & support | 2025 |
| Style Mentoring Ltd | Information & communication | 2024 |
| Stylefloor Limited | Construction | 2008 |
| Stylez & Smilez Ltd | Other services | 2018 |
| Sugar Wholesale Alliance Limited | Wholesale & retail | 2025 |
| Suhana Spice Ltd | Hospitality | 2019 |
| Sulaman Services Limited | Information & communication | 2013 |
| Summerside Investments Limited | Hospitality | 2015 |
| Sun Financial Limited | Financial services | 2019 |
| Sunday Healthcare Resources Limited | Administrative & support | 2025 |
| Sunhay Limited | Wholesale & retail | 1992 |
| Sunnybank Motors Limited | Wholesale & retail | 2009 |
| Sunnyhurst Stores Ltd | Wholesale & retail | 2020 |
| Superior Contract Soft Furnishings Ltd | Wholesale & retail | 2015 |
| Supreme Services (NW) Ltd | Professional & scientific | 2021 |
| Surge E-Liquids Limited | Wholesale & retail | 2025 |
| Susan Collier Limited | Wholesale & retail | 2001 |
| Susan Hilton Limited | Health & social care | 2004 |
| Suzanne Dennis Optometrist Limited | Health & social care | 2005 |
| Sweeteq Labs Ltd | Manufacturing | 2025 |
| Sympol Limited | Information & communication | 2017 |
| Synergy Motor Sales Ltd | Wholesale & retail | 2015 |
| SZ Newsagents Limited | Wholesale & retail | 2018 |
| T & S Legal Ltd | Professional & scientific | 2022 |
| T Gardner Plumbing & Heating Limited | Construction | 2002 |
| T K Transport Ltd | Transport & logistics | 2025 |
| T LEA Holdings Limited | Real estate | 2024 |
| T Walker Limited | Manufacturing | 2008 |
| T&A Prestige Properties Ltd | Real estate | 2024 |
| T&Khousing Ltd | Real estate | 2022 |
| T'Near Ltd | Real estate | 2020 |
| T.J Crompton Limited | Health & social care | 2002 |
| T.J. Lift Solutions Ltd. | Manufacturing | 2003 |
| Tagcare Ltd | Extraterritorial | 2025 |
| Tagtronics Limited | Information & communication | 2000 |
| Tamsha Ltd | Hospitality | 2025 |
| TAN Ranch Limited | Other services | 2024 |
| Tania Climate Engineering Ltd | Construction | 2026 |
| Taps Darwen Ltd | Hospitality | 2020 |
| Taskjump Limited | Information & communication | 2022 |
| Tasty Village Ltd | Hospitality | 2018 |
| Taylor Biddle Holdings Limited | Other services | 2012 |
| Taylor Biddle Opticians Ltd | Health & social care | 2010 |
| Taylor Bros Holdings Ltd | Real estate | 1984 |
| Taylor Country Cottages Ltd | Construction | 2019 |
| Taylor Country Homes (Bartle) Ltd | Construction | 2021 |
| Taylor Country Homes Limited | Construction | 2016 |
| Taylor Procter Ltd | Other services | 2019 |
| TB Rooflines Limited | Construction | 2019 |
| TC YUM Ltd | Hospitality | 2021 |
| TCB Roofing & Building Ltd | Construction | 2022 |
| Team Locations Ltd | Information & communication | 2024 |
| Team Renovation Solutions Ltd | Construction | 2024 |
| Tech Solutions and Imports Ltd | Wholesale & retail | 2025 |
| Techfloor Services Limited | Wholesale & retail | 2005 |
| Technasaur Ltd | Information & communication | 2024 |
| Techno Coat Limited | Administrative & support | 2004 |
| Techshop Online Limited | Wholesale & retail | 2019 |
| Teddy's Retreat Ltd | Other services | 2023 |
| Tee-Khi Foods Limited | Other services | 2013 |
| Teegiftideas Limited | Wholesale & retail | 2025 |
| Telford Optical Limited | Wholesale & retail | 2026 |
| Tempest Logistics Ltd | Transport & logistics | 2021 |
| Temple Estates 1985 Ltd | Real estate | 2026 |
| Temple Kitchen Limited | Hospitality | 2025 |
| Temple of FUN Ltd | Arts & recreation | 2022 |
| Temporary Kitchen Solutions Ltd | Construction | 2025 |
| TEN Senses Ltd | Manufacturing | 2016 |
| Ten/Ten Foods Ltd | Hospitality | 2024 |
| TERRA97 Ltd | Construction | 2017 |
| Terranean Tiles Ltd | Construction | 2023 |
| Terry and Associates Limited | Health & social care | 2010 |
| THD Demolition Limited | Construction | 2015 |
| THE 180 Programme C.I.C. | Administrative & support | 2018 |
| THE Alder Lounge Ltd | Hospitality | 2023 |
| THE Alexandra Darwen Ltd | Hospitality | 2025 |
| THE Arizon Network CIC | Professional & scientific | 2025 |
| THE Artisans Alchemy Ltd | Education | 2025 |