| Sempahore Resources Ltd | Information & communication | 2025 |
| Send IT Sounds Ltd | Information & communication | 2025 |
| Shackleton Construction Limited | Construction | 2014 |
| Shawstephens Limited | Manufacturing | 2008 |
| Shoalstone Consultants Ltd | Construction | 2019 |
| Shoalstone Property Ltd | Construction | 2021 |
| Sifft Ltd | Information & communication | 2025 |
| SJP IFA Limited | Financial services | 2016 |
| Smuntz Limited | Professional & scientific | 2022 |
| Southern Homes (Lettings) Limited | Real estate | 2003 |
| Sparkles-Jewellery Ltd | Wholesale & retail | 2026 |
| Speedwell Holdings Ltd | Real estate | 2021 |
| Sphere Marketing Network Ltd | Other services | 2024 |
| Spice Bazaar Dartmouth Ltd | Hospitality | 2018 |
| Spirit of Tradition Ltd | Wholesale & retail | 2014 |
| Spryng Consulting Ltd | Information & communication | 2021 |
| ST Albans PUB Co Limited | Hospitality | 2022 |
| Start Bay Build Limited | Construction | 2022 |
| Start Bay Enterprises Ltd | Professional & scientific | 2023 |
| Startpoint Advisory Services Limited | Professional & scientific | 2025 |
| Steve Smither Flooring Limited | Construction | 2016 |
| Stokecliff Management Company Limited | Hospitality | 1977 |
| Stone's Throw Farm Ltd | Agriculture & fishing | 2021 |
| Strategic Dynamics Consultancy Services Limited | Professional & scientific | 2005 |
| Swell Consultants Limited | Professional & scientific | 2015 |
| Swell Devon Ltd | Hospitality | 2020 |
| Tacs(Dartmouth) Ltd. | Professional & scientific | 2017 |
| Talking Psychology Ltd | Health & social care | 2022 |
| Tanismans Ltd | Other services | 2025 |
| Taunton Manor Properties Ltd | Real estate | 2020 |
| Taylor's of Dartmouth Limited | Hospitality | 2002 |
| Tessa Moore Consulting Ltd | Professional & scientific | 2011 |
| THE Advisory Guild Limited | Professional & scientific | 2025 |
| THE Big Blue BAG CIC | Education | 2024 |
| THE Britannia Association | Other services | 2014 |
| THE Dartmouth Building Company Ltd | Construction | 2017 |
| THE Dartmouth DUO & Co. Ltd | Hospitality | 2025 |
| THE Dartmouth Plumbing Company Ltd | Construction | 2026 |
| THE Dartmouth Property Company Ltd | Real estate | 2018 |
| THE Devon Dog Wash Co Ltd | Other services | 2024 |
| THE Devon House Ltd | Wholesale & retail | 2022 |
| THE Gramophone Company Limited | Information & communication | 2013 |
| THE Green Hair Company Ltd | Wholesale & retail | 2025 |
| THE Manor House (Dartmouth) Freehold Limited | Households | 2024 |
| THE Pink Manta Club Ltd | Professional & scientific | 2025 |
| THE Really Useful Cleaning Company Ltd | Extraterritorial | 2025 |
| THE Remarkable Goldsmiths Ltd | Manufacturing | 2019 |
| THE Salcombe Creperie Ltd | Wholesale & retail | 2022 |
| THE Totnes Curtain Studio Limited | Manufacturing | 2022 |
| THE Venus Company Limited | Wholesale & retail | 1998 |
| THE White Laundry Company Limited | Other services | 2016 |
| Therapy Tree Limited | Health & social care | 2018 |
| Thomas Newcomen CIC | Administrative & support | 2026 |
| Tiger Building Development Limited | Real estate | 2018 |
| Topolab Limited | Information & communication | 2024 |
| TR 23 Limited | Hospitality | 2018 |
| Transaction Services Limited | Professional & scientific | 2017 |
| Trattoria Spaggia Limited | Hospitality | 2026 |
| Trda Management Limited | Households | 2025 |
| Trinity Jerky Ltd | Wholesale & retail | 2025 |
| TS Feast Limited | Hospitality | 2022 |
| Tudor Lodge Property Management Limited | Households | 2017 |
| UK Crown Limited | Administrative & support | 2011 |
| Umber and Ecru Ltd | Manufacturing | 2020 |
| Universal Sourcing Limited | Wholesale & retail | 2013 |
| Unravelled Ltd | Education | 2019 |
| Upside Down Games Ltd | Information & communication | 2010 |
| Urban Wellbeing Solutions Limited | Professional & scientific | 2018 |
| V S J Marquee Hire Limited | Administrative & support | 1997 |
| Vaughan Medical Ltd | Health & social care | 2010 |
| Ventera Limited | Water & waste | 2010 |
| Verdure Associates Limited | Professional & scientific | 2019 |
| Visit Dartmouth Limited | Administrative & support | 2020 |
| W8M8 Ltd | Information & communication | 2023 |
| Walkwyse Ltd. | Information & communication | 2021 |
| Wardcon Limited | Administrative & support | 2016 |
| Waterhead Close Management (Kingswear) Limited | Water & waste | 2002 |
| Watermill Cottages Limited | Hospitality | 2009 |
| Weeke Management Limited | Real estate | 2019 |
| Wesley Court Management Company (Dartmouth) Limited | Professional & scientific | 1993 |
| West Plumbing Services Ltd | Construction | 2018 |
| Westaway & Westaway Limited | Wholesale & retail | 2016 |
| Westcountry Access Limited | Construction | 2005 |
| Westwater Court Management Company Limited | Households | 2012 |
| White Ladies Management Company Limited | Households | 1981 |
| White Pump Properties Limited | Real estate | 2025 |
| WHK Services Devon Limited | Administrative & support | 2011 |
| Wilfred 14 LLP | | 2018 |
| Windlee Management Co Ltd | Households | 2011 |
| Woodbury Farm Holiday Cottages Ltd | Hospitality | 2014 |
| Xpajun Off-Road Ltd | Manufacturing | 2013 |
| Y0UGR0UP5 Ltd | Professional & scientific | 2023 |
| Yandina Limited | Agriculture & fishing | 2014 |
| Yorke Finance Limited | Financial services | 2006 |
| YUM YUM London Ltd | Information & communication | 2010 |
| Zendenz Limited | Hospitality | 2017 |
| Zeta Motion Ltd | Information & communication | 2019 |
| Zictech Technologies Ltd | Wholesale & retail | 2026 |
| Zublu Limited | Administrative & support | 2017 |