| Unik Foods Limited | Hospitality | 2019 |
| Union Shipping Limited | Transport & logistics | 1998 |
| Unique Interiors (London) Limited | Wholesale & retail | 2002 |
| Unique Key Properties Ltd | Real estate | 2024 |
| Unique Skills Driving Academy Ltd | Professional & scientific | 2025 |
| UNIQUE30 Ltd | Administrative & support | 2016 |
| Unit 4 ESQ Ltd | Real estate | 2024 |
| UNITE19 Ltd | Arts & recreation | 2019 |
| United Creatives Agency Limited | Information & communication | 2024 |
| Unitey Football Club Ltd | Arts & recreation | 2025 |
| UNITMANAGER1 Limited | Information & communication | 2018 |
| Univarsity Ltd | Professional & scientific | 2025 |
| Universal Beverage Company (East) Limited(The) | | 1986 |
| Universal Installation & Maintenance Services Limited | Energy | 2001 |
| Universal Lift Repairs Limited | Manufacturing | 2018 |
| Universal Properties (Europe) Limited | Administrative & support | 1996 |
| Universal Trading London Ltd | Wholesale & retail | 2020 |
| Universita Analytics Solution Limited | Information & communication | 2025 |
| Univista Limited | Wholesale & retail | 2025 |
| Unos Construction Limited | Construction | 2025 |
| Unwind Worldwide Limited | Administrative & support | 2009 |
| Unyte Ltd | Information & communication | 2023 |
| UP and Away Holidays Limited | Professional & scientific | 2003 |
| UP and Away Limited | Administrative & support | 1994 |
| UP Textile Ltd | Wholesale & retail | 2024 |
| UP There Roofing Ltd | Construction | 2026 |
| Uplift Wellness Ltd | Arts & recreation | 2026 |
| Upminster Group Ltd | Real estate | 2020 |
| Uprate Digital Ltd | Professional & scientific | 2021 |
| Upscale Digital Marketing Ltd | Professional & scientific | 2024 |
| Upsteady Ltd | Professional & scientific | 2019 |
| Uptown Recruitment Ltd | Administrative & support | 2024 |
| Uptown Solutions Limited | Construction | 2010 |
| Upvolt Kent Ltd | Construction | 2017 |
| Upwardz Ltd | Professional & scientific | 2023 |
| UR Local Convenience Store Limited | Wholesale & retail | 2024 |
| Urbacon Technologies & Services Ltd | Information & communication | 2023 |
| Urban Logik Limited | Professional & scientific | 2014 |
| Urban Nurture Co Limited | Health & social care | 2026 |
| Urban Sticks Mortgage Solutions Ltd | Financial services | 2017 |
| Urbin Waste Limited | Water & waste | 2023 |
| Urhobo Progress Union UK | Other services | 2022 |
| US Express Limited | Real estate | 2015 |
| USC Construction Limited | Construction | 2019 |
| Usha Communications Limited | Information & communication | 2019 |
| Usha London Ltd | Wholesale & retail | 2025 |
| Usher Dependable Services Limited | Information & communication | 2023 |
| Ustigate G.R.P. Limited | Construction | 2008 |
| Ustigate Limited | Administrative & support | 1993 |
| Utima Limited | Hospitality | 2020 |
| Utmost Solutions Limited | Hospitality | 2019 |
| Utopia Designer Limited | Wholesale & retail | 2021 |
| Utopia IX Limited | Other services | 2020 |
| Utpa Limited | Other services | 2024 |
| Utrade Ltd | Construction | 2019 |
| Uvia Herbals Ltd | Manufacturing | 2026 |
| Uwill Global Ltd | Education | 2019 |
| V and LU Ltd | Wholesale & retail | 2026 |
| V CAN Resources Limited | Wholesale & retail | 2021 |
| V H IT Ltd. | Information & communication | 2022 |
| V K Homes Ltd | Real estate | 2016 |
| V Plus Ltd | Other services | 2009 |
| V Property Services Limited | Construction | 2024 |
| V R Facades Ltd | Construction | 2019 |
| V Rejuvederm Aesthetic Clinic Ltd | Health & social care | 2021 |
| V Rivers Ltd | Construction | 2017 |
| V&F Premier Services Ltd | Construction | 2026 |
| V&H Construction Group Ltd | Construction | 2021 |
| V&S Property Solutions Ltd | Real estate | 2023 |
| V&V Media Ltd | Professional & scientific | 2026 |
| V. Zugravu Limited | Construction | 2016 |
| V.I.P. Limited | Professional & scientific | 1982 |
| V3 Services Limited | Administrative & support | 2017 |
| V6 Recovery Services Ltd | Transport & logistics | 2025 |
| Vacation Care International Limited | Other services | 1989 |
| Vaci Limited | Wholesale & retail | 2020 |
| Vael Ltd | Wholesale & retail | 2024 |
| Vafmel Investments Limited | Real estate | 2024 |
| Vagolis Limited | Construction | 2012 |
| Vaio Trans Ltd | Transport & logistics | 2024 |
| Valai Homes Limited | Real estate | 2024 |
| Valai Limited | Information & communication | 2011 |
| Valdy Ltd | Construction | 2024 |
| Vale Private Road Management Limited | Households | 2015 |
| Valerie Bryan Limited | Administrative & support | 2015 |
| Valiant Scaffolding Ltd | Construction | 2020 |
| Valiconstruct Ltd | Construction | 2026 |
| Validus Finance Solutions Ltd | Professional & scientific | 2017 |
| Valley Provincial Global Ltd | Financial services | 2022 |
| Valley Provincial Group LLP | | 2012 |
| Valley Provincial Holdings Ltd | Financial services | 2022 |
| Valley Provincial Ltd | Construction | 2022 |
| Valley Road 1954 Limited | Extraterritorial | 2013 |
| Valor Training Ltd | Education | 2025 |
| Valorevents Ltd | Administrative & support | 2010 |
| VAM Contracts Ltd | Construction | 2018 |
| Vanel Ltd | Real estate | 2024 |
| Vanguard Business Advisors Ltd | Professional & scientific | 2021 |
| Vanquish Electrical & Data Services Ltd | Construction | 2022 |
| Vanquish Interiors Limited | Construction | 2015 |