| Seniate Limited | Other services | 2022 |
| Sense the Breeze Ltd | Professional & scientific | 2018 |
| Sensory Design and Install Limited | Construction | 2025 |
| Sensory Everywhere Educational Services Limited | Education | 2022 |
| Sensory Solution Wholesale Ltd | Wholesale & retail | 2025 |
| Sent Holdings Limited | Health & social care | 2023 |
| Sentinel Remote Community Limited | Administrative & support | 2026 |
| Sentinel Remote Limited | Financial services | 2026 |
| Sentinel Remote Response Limited | Administrative & support | 2026 |
| Sentinel Remote Security Limited | Administrative & support | 2026 |
| Sentinel Remote Survey Limited | Professional & scientific | 2026 |
| Sentinel Response Limited | Administrative & support | 2026 |
| Sentinel Technology Systems Ltd | Information & communication | 2025 |
| Septini Ltd | Professional & scientific | 2024 |
| Serenity Assets Ltd | Real estate | 2019 |
| Serenity Rentals Limited | Hospitality | 2023 |
| Serenity Sips Ltd | Hospitality | 2025 |
| Serk's General Motors Ltd | Wholesale & retail | 2026 |
| Sero Labs Ltd. | Wholesale & retail | 2024 |
| Service Management Solutions Group Ltd | Professional & scientific | 2020 |
| Service Motors Limited | Wholesale & retail | 2001 |
| Serviced Travel Stays Ltd | Real estate | 2026 |
| Servienvios UK Limited | Transport & logistics | 2014 |
| SES Lifts Limited | Manufacturing | 2007 |
| Setting OUT and Survey Engineer Ltd | Construction | 2025 |
| Seven Brands Global Limited | Administrative & support | 2019 |
| Seven Design & Build Ltd | Construction | 2017 |
| Seven Motorsport Limited | Wholesale & retail | 2016 |
| Seven Sisters F&B Ltd | Hospitality | 2024 |
| Seven SIX DUO Ltd | Wholesale & retail | 2026 |
| Sevenark Limited | Real estate | 2003 |
| Sevenfields New Barn | | 1986 |
| Sevenoaks Garden Centre Limited | Wholesale & retail | 2020 |
| Sevenoaks House Clearance Services Ltd | Transport & logistics | 2025 |
| Sevenoaks Sushi Ltd | Hospitality | 2025 |
| Sevvel Brother Limited | Wholesale & retail | 2025 |
| SEW Crafty Limited | Other services | 2007 |
| SF Resources Limited | Professional & scientific | 2014 |
| Sfencombe Ltd | Financial services | 2025 |
| Sfix Ltd | Construction | 2017 |
| Sfmc Ltd | Construction | 2022 |
| SG Deco Ltd | Construction | 2023 |
| SG Electrical Installations Ltd | Construction | 2015 |
| SG Facilities Ltd | Construction | 2022 |
| SG Surveying Ltd | Professional & scientific | 2024 |
| Sgjb Group Limited | Financial services | 2025 |
| Sgjb Properties Limited | Households | 2025 |
| SGS Electrical Contractors Limited | Construction | 2008 |
| SH Sparkles Ltd | Real estate | 2022 |
| Shab Shaz Properties Ltd | Real estate | 2024 |
| Shabach Solutions Ltd | Information & communication | 2018 |
| Shabanie Socio-Healthcare Services Limited | Health & social care | 2021 |
| Shabol Management Services Ltd | Public administration | 2019 |
| Shadekhiat Creations Limited | Wholesale & retail | 2026 |
| Shadow FOX Ltd | Health & social care | 2010 |
| Shady Yoyo Ltd | Information & communication | 2024 |
| Shafaa Tech Limited | Information & communication | 2012 |
| Shaftesbury Equestrian Centre Ltd | Agriculture & fishing | 2025 |
| Shaheen Consulting Limited | Administrative & support | 2024 |
| Shahi Builders Ltd | Construction | 2017 |
| Shahi Property Investments Ltd | Real estate | 2024 |
| Shahsan Ltd | Transport & logistics | 2024 |
| Shai Hills Development Ltd | Construction | 2025 |
| Shakthi Limited | Construction | 2014 |
| Shallsell Electrical Services (UK) Limited | Construction | 2017 |
| Shalom Healthcare Services Ltd | Administrative & support | 2025 |
| Shameless Media Limited | Professional & scientific | 2026 |
| Shamsa MUA Ltd | Other services | 2021 |
| Shan & Safin Limited | Wholesale & retail | 2016 |
| Shan Fisheries Ltd | Wholesale & retail | 2020 |
| Shangeeth Ltd | Health & social care | 2025 |
| Shanghai Seda UK Ltd | Information & communication | 2022 |
| Shaniel Properties Limited | Real estate | 2023 |
| Shapeu Cleaning Service Ltd | Administrative & support | 2020 |
| Shapeu Training and Consulting Ltd | Administrative & support | 2021 |
| Shardlake Investment LLP | | 2014 |
| Sharkpto Ltd | Wholesale & retail | 2024 |
| SHARMA1 Management Limited | Professional & scientific | 2022 |
| Sharnal Street Developments Limited | Construction | 2021 |
| Sharon Eden Ltd | Information & communication | 2022 |
| Sharp Practice (London) Limited | Administrative & support | 2017 |
| Sharpen Your Skills Ltd | Hospitality | 2024 |
| Shaw Wood Demolition Ltd | Construction | 2023 |
| Shaw Wood Environmental Ltd | Extraterritorial | 2023 |
| Shaw Wood Group Ltd | Extraterritorial | 2023 |
| Shaw Wood Ltd | Construction | 2022 |
| Shaw Wood Plant Hire Ltd | Administrative & support | 2023 |
| Shaw Wood Properties Ltd | Financial services | 2024 |
| Shaw Wood Property Holdings Ltd | Real estate | 2025 |
| Shazgaz Estates Limited | Real estate | 2025 |
| Shears Close Residents Association Limited | Households | 2000 |
| Sheet Metal Industries Ltd | Information & communication | 2022 |
| Sheffman Ltd | Professional & scientific | 2015 |
| SHEGZ1 Ltd | Construction | 2020 |
| Shekaf Ltd | Real estate | 2023 |
| Shekhinah Global Ltd | Information & communication | 2020 |
| Shellah Investments Ltd | Health & social care | 2018 |
| Shells Properties Ltd | Real estate | 2020 |
| Shepherd Hill Petroleum Development Ltd. | Mining & quarrying | 2015 |
| Shepherds Food Limited | Hospitality | 2025 |