| Yilley Ltd | Health & social care | 2014 |
| YM Autocare Ltd | Wholesale & retail | 2021 |
| Yoga & YOU Limited | Extraterritorial | 2010 |
| Yoga for YOU Ltd | Education | 2024 |
| Yogaizzz Ltd | Arts & recreation | 2023 |
| Yomeela Properties Limited | Real estate | 2021 |
| Yoorikaa Ltd | Professional & scientific | 2023 |
| York House (Liverpool) Management Limited | Households | 2002 |
| York Riverside Apartments Limited | Real estate | 2025 |
| Yorkshire 4X4 Limited | Arts & recreation | 2009 |
| Yorkshire Outdoor Adventures Ltd | Arts & recreation | 2023 |
| Yorkshire Weddings & Events Ltd | Other services | 2015 |
| Yorsafety Limited | Professional & scientific | 2020 |
| YOU GOT Nails Limited | Other services | 2004 |
| Young Property Services Ltd | Construction | 2020 |
| Your Bespoke North Limited | Manufacturing | 2020 |
| Your Learning Journey Limited | Information & communication | 2020 |
| Your Local Darlington Limited | Wholesale & retail | 2025 |
| Your Mckenzie Friend Ltd | Professional & scientific | 2025 |
| Your Stylish Stay Management Ltd | Real estate | 2024 |
| Yourpet Ltd | Wholesale & retail | 2011 |
| Youzilov Ltd | Wholesale & retail | 2025 |
| YR 909 Limited | Hospitality | 2023 |
| Yuma Botanics Limited | Wholesale & retail | 2026 |
| Yuze Technologies Limited | Wholesale & retail | 2020 |
| Z Electricians Limited | Construction | 2017 |
| ZA Smile Centre Ltd | Health & social care | 2019 |
| ZAC Antonaci Limited | Information & communication | 2025 |
| Zage Collective Ltd | Information & communication | 2022 |
| Zahoor Abbas Ltd | Transport & logistics | 2017 |
| Zaitlinelogistics Ltd | Transport & logistics | 2026 |
| ZAM ZAM NE Ltd | Hospitality | 2025 |
| Zameen Holdings Ltd | Real estate | 2025 |
| Zapbyte Ltd | Construction | 2025 |
| Zborowski Group Limited | Information & communication | 2022 |
| Zebco Heating Ltd | Manufacturing | 2021 |
| Zebra Plumbing and Heating Limited | Construction | 2022 |
| ZED Consultancy NE Ltd | Professional & scientific | 2026 |
| Zeus Industries Limited | Real estate | 2016 |
| Zeus Properties(Uk) Ltd | Real estate | 2014 |
| ZIG ZAG Cars Limited | Wholesale & retail | 2004 |
| Zigup Corporate Services Limited | Administrative & support | 2019 |
| Zigup PLC | Financial services | 1897 |
| Zinga Fresh Chicken Ltd | Hospitality | 2026 |
| Zinga Fried Chcken Ltd | Hospitality | 2025 |
| Zoe's Property Maintenance Renovation Limited | Households | 2025 |
| Zofi Care Limited | Health & social care | 2025 |
| ZOG Global Ltd | Information & communication | 2019 |
| Zunaim Trading Ltd | Wholesale & retail | 2025 |
| Zynex Systems Limited | Wholesale & retail | 2025 |
| Zyro Limited | Wholesale & retail | 1995 |
| Ádhmall Limited | Financial services | 2025 |
| Über Guard Security Ltd | Administrative & support | 2025 |