| Valhalla North Ltd | Arts & recreation | 2019 |
| Valtay Homes Ltd | Real estate | 2021 |
| Valve Asset Solutions Ltd | Professional & scientific | 2020 |
| Van Trader NE Limited | Wholesale & retail | 2025 |
| Van-Jo Property Development Ltd | Real estate | 2023 |
| Vancouver House Ltd | Construction | 2006 |
| Vane Terrace Residents Management Co Ltd | Households | 2025 |
| Vanguard Property Care Ltd | Construction | 2026 |
| Vantage Global Ltd | Manufacturing | 2013 |
| Vape City Darlington Ltd | Wholesale & retail | 2026 |
| Vape Inc Darlington Limited | Wholesale & retail | 2024 |
| Vape Suite Darlington Ltd | Wholesale & retail | 2023 |
| Vapor OPS Ltd | Wholesale & retail | 2025 |
| Varda Roofing Ltd | Construction | 2026 |
| Vasa Properties Limited | Real estate | 2026 |
| Vasstech (Darlington) Limited | Wholesale & retail | 2011 |
| VAT Practitioners Group Limited | Administrative & support | 2018 |
| VCD Limited | Information & communication | 2018 |
| VDL Equipment UK (Exclusive Distributors) Limited | Manufacturing | 2024 |
| VDM Holdings Limited | Real estate | 2021 |
| VDM Investments Ltd | Real estate | 2020 |
| Vdtrans Ltd | Transport & logistics | 2019 |
| Vector Building and Roofing Contractors Ltd | Construction | 2023 |
| VEG House Limited | Manufacturing | 2021 |
| Vehicle Access Ltd | Wholesale & retail | 2023 |
| Vehicle Movement 21 Ltd | Transport & logistics | 2022 |
| Vehicle Vault North East Ltd | Wholesale & retail | 2024 |
| Vehicle Wraps Yorkshire Limited | Wholesale & retail | 2021 |
| Vellaris Hub Limited | Manufacturing | 2026 |
| Venos Pizzaria Limited | Hospitality | 2016 |
| Venture Properties (CLS) Limited | Real estate | 2011 |
| Venture Properties (Crook) Limited | Real estate | 2012 |
| Venture Properties (Durham) Limited | Real estate | 2013 |
| Venture Properties (North East) Limited | Real estate | 2008 |
| Verbera Limited | Information & communication | 2022 |
| Vercet Limited | Professional & scientific | 2006 |
| Verde Luxury Travel Ltd | Administrative & support | 2024 |
| Veri Properties Limited | Real estate | 2025 |
| Verismart North East Ltd | Other services | 2020 |
| Vernon Hill Limited | Construction | 2019 |
| Vernujan Ltd | Wholesale & retail | 2020 |
| Verostanca Ltd | Transport & logistics | 2025 |
| Versena Ltd | Wholesale & retail | 2017 |
| Verve Holdings Ltd | Professional & scientific | 2018 |
| VF Roofing Ltd | Construction | 2021 |
| VG Developments (NE) Ltd | Real estate | 2017 |
| VGD Ltd | Construction | 2024 |
| VHG Limited | Wholesale & retail | 2026 |
| VI Saxum Ltd | Real estate | 2021 |
| Vibrant Feeling Ltd | Health & social care | 2015 |
| Vibrant Foodstate Limited | Wholesale & retail | 2019 |
| Vickers Holdings (MSG) Limited | Financial services | 2024 |
| Vickers.Bet Ltd | Arts & recreation | 2019 |
| Vickycowie.Com Limited | Information & communication | 2019 |
| Victoria Mcguire Ltd | Administrative & support | 2022 |
| Victoria Road (Darlington) Commonhold Association Limited | Households | 2004 |
| Victoria Road Holdings Ltd | Real estate | 2018 |
| Vida Financial Planning Limited | Financial services | 2019 |
| VIDEO53 Limited | Administrative & support | 2023 |
| View Developments Limited | Real estate | 2004 |
| Viiio Ltd | Professional & scientific | 2023 |
| Viking Film and Television Limited | Information & communication | 2005 |
| Village Supermarket 1 Ltd | Wholesale & retail | 2026 |
| Vincent House (Darlington) Management Company Limited | Real estate | 2007 |
| Vinco Technologies Limited | Information & communication | 2023 |
| VIO Trans Deliver Limited | Transport & logistics | 2025 |
| VIP Place Ltd | Real estate | 2023 |
| VIP TAN Darlington Ltd | Wholesale & retail | 2019 |
| Vipauk Ltd | Information & communication | 2010 |
| Viprvi Ltd | Health & social care | 2014 |
| Virtix Ltd | Wholesale & retail | 2026 |
| Virtual Fairways NE Ltd | Arts & recreation | 2025 |
| Virtus Build & Plaster Ltd | Construction | 2015 |
| Virtutis Ltd | Professional & scientific | 2026 |
| Vision 34 Developments Ltd | Real estate | 2020 |
| Vision Electrical & Commissioning Limited | Construction | 2015 |
| VISION34 UK Ltd | Professional & scientific | 2020 |
| Vitacoll Limited | Hospitality | 1998 |
| Vital Acre Trading Ltd | Wholesale & retail | 2025 |
| Vitality Construction Services Limited | Construction | 2017 |
| Vitascend Ltd | Health & social care | 2025 |
| Vivanta Properties Limited | Real estate | 2025 |
| Vixi Fitness Limited | Education | 2025 |
| VJ Ventures Limited | Hospitality | 2014 |
| Vjuzon Properties Ltd | Real estate | 2020 |
| Vl.Infectionprevention Ltd | Health & social care | 2016 |
| VOG Interiors Ltd | Construction | 2015 |
| Voidfiend Ltd | Wholesale & retail | 2025 |
| Volt-Ride NE Limited | Wholesale & retail | 2026 |
| Vorsterbutler Ltd | Professional & scientific | 2026 |
| Vortecs Limited | Information & communication | 1996 |
| Vortex Strategic Aviation Solutions Ltd | Manufacturing | 2026 |
| Voxel Games Ltd | Information & communication | 2023 |
| VP360 Limited | Construction | 2013 |
| VQB Holdings Ltd | Real estate | 2022 |
| Vralio Limited | Wholesale & retail | 2025 |
| VSM Access Ltd | Construction | 2026 |
| Vulcan Flooring Suppliers Limited | Construction | 2008 |
| Vvarda Ltd | Construction | 2025 |
| Vycore Limited | Information & communication | 2025 |