| EPA Concepts Limited | Other services | 2019 |
| Escapade 9 Ltd | Construction | 2024 |
| ESI Process U.K. Limited | Wholesale & retail | 2001 |
| Essential Elec Services Ltd | Professional & scientific | 2025 |
| Essenza Lifestyle Ltd | Wholesale & retail | 2025 |
| Esti-Quant Ltd | Professional & scientific | 2024 |
| Etheridge Plant Hire Limited | Construction | 1994 |
| Ethos Properties SW Ltd | Real estate | 2024 |
| Euphros Psychometrics Ltd | Administrative & support | 2021 |
| Euro Foods (UK) Limited | Manufacturing | 2014 |
| Euro Foods Group Limited | Manufacturing | 1995 |
| Evactus Ltd | Professional & scientific | 2026 |
| Evening Tt&W Ltd | Transport & logistics | 2018 |
| Evergreen Investment and Development Limited | Construction | 2026 |
| Evergreen Investment and Letting Limited | Real estate | 2026 |
| Everstrong Carpentry Limited | Manufacturing | 2026 |
| Everstrong Construction Ltd | Construction | 2025 |
| Eveswood Limited | Extraterritorial | 2020 |
| Evo-Holdings Limited | Construction | 2025 |
| Evobead Limited | Administrative & support | 2017 |
| Evolution IT Solutions Limited | Information & communication | 2006 |
| Evolution Private Finance Ltd. | Financial services | 2015 |
| Evolve (Wales) | Education | 2012 |
| Evolve Home Energy Solutions Ltd | Construction | 2015 |
| Evosh Ltd | Real estate | 2025 |
| Evwin Limited | Manufacturing | 1982 |
| Exclusive (EX) Limited | Construction | 2010 |
| Expanding Horizons Ltd | Health & social care | 2005 |
| Extract Air Solutions Ltd | Construction | 2018 |
| F J Systems Ltd | Information & communication | 2026 |
| F.M Investment Holdings Ltd | Wholesale & retail | 2021 |
| Fabargains Ltd | Wholesale & retail | 2018 |
| Fairprice Distribution Ltd | Wholesale & retail | 2024 |
| Fairwater Clean Centre Limited | Other services | 2013 |
| Faiwater Cafe Cwmbran Ltd | Hospitality | 2025 |
| Family Kebab Caerphilly Limited | Hospitality | 2011 |
| Familykebab Ltd | Hospitality | 2026 |
| Farm-Iq Limited | Information & communication | 2025 |
| Fast Fit Recovery Ltd | Transport & logistics | 2022 |
| Fast Soft Drink Ltd | Hospitality | 2025 |
| Fatel Ltd. | Health & social care | 2015 |
| FCY Interiors Ltd | Construction | 2018 |
| Fear Financial Ltd | Financial services | 2023 |
| Femstario Real Estates Ltd | Real estate | 2023 |
| Festive Productions Limited | Manufacturing | 1983 |
| FF Autocentre Ltd | Wholesale & retail | 2023 |
| Fibre Forge UK Ltd | Information & communication | 2025 |
| Fibre Offshore Communications Limited | Construction | 2026 |
| Fike Safety Technology Ltd | Manufacturing | 1994 |
| Financial Planning Solutions Limited | Financial services | 2008 |
| Finnells Legal Services Limited | Administrative & support | 2014 |
| Fiona Nicole Ltd | Professional & scientific | 2017 |
| Fircroft Holdings Limited | Administrative & support | 2021 |
| Fircroft Technologies Ltd | Administrative & support | 2001 |
| First Physio Limited | Health & social care | 1995 |
| Fitzgerald Plant Properties Limited | Real estate | 2021 |
| Fitzgerald Plant Services Limited | Manufacturing | 2007 |
| Five Star Breeders Ltd | Administrative & support | 2017 |
| Flawsome Brands Ltd | Wholesale & retail | 2016 |
| Fleet Mobile Mechanics Ltd | Wholesale & retail | 2025 |
| Flo-Screed UK Limited | Construction | 2005 |
| Floorex Carpets Limited | Wholesale & retail | 1985 |
| Flow N Flame Ltd | Construction | 2025 |
| Flowmech Services Limited | Construction | 2022 |
| Flowtech P+H Services Ltd | Construction | 2025 |
| Floxton Limited | Professional & scientific | 2011 |
| FMK Electrical Services Ltd | Construction | 2025 |
| Focus Comms Ltd | Construction | 2025 |
| Focus Ideals Limited | Professional & scientific | 1999 |
| FOG Technologies Ltd | Financial services | 2020 |
| Fogcheck Ltd | Water & waste | 2020 |
| Fogtec Limited | Professional & scientific | 2024 |
| Fogtech Ltd | Professional & scientific | 2020 |
| Foodstix Limited | Hospitality | 2021 |
| Foodstix Trading Limited | Hospitality | 2021 |
| Forgehammer Community Social Club CIC | Hospitality | 2023 |
| Formula Prestige Comps Ltd | Other services | 2025 |
| Formula Prestige Motors Ltd | Administrative & support | 2016 |
| Forseti MC Ltd | Real estate | 2025 |
| Fourgreen Developments Limited | Real estate | 1994 |
| FOX Group (Moving & Storage) Limited | Transport & logistics | 2017 |
| FOX Holdings (Moving & Storage) Limited | Financial services | 2024 |
| FOX Self Storage Limited | Transport & logistics | 1982 |
| Franthea Limited | Financial services | 2023 |
| Freham Properties Limited | Real estate | 2024 |
| Friends for Pets Newport Limited | Other services | 2019 |
| FSG Global Limited | Financial services | 2022 |
| FSG Oceania Limited | Professional & scientific | 2022 |
| Fuelling Change Ltd | Professional & scientific | 2022 |
| Full Throttle Garage Ltd | Wholesale & retail | 2026 |
| G & G (Cwmbran) Limited | Construction | 2017 |
| G & N Logistics Limited | Transport & logistics | 2009 |
| G & N Transport Ltd | Transport & logistics | 2015 |
| G L & C a Poultry Limited | Agriculture & fishing | 2005 |
| G M Plant Repairs Limited | Manufacturing | 2013 |
| G P Electrics & Services Ltd | Construction | 2025 |
| G T Toms Discount Mot,S Ltd | Wholesale & retail | 2021 |
| G&D Structures Ltd | Construction | 2023 |
| G&I Properties Ltd | Real estate | 2024 |
| G.H.P Mechanical and Electrical Limited | Construction | 2026 |