| DRG Precision Build and Decor Limited | Construction | 2016 |
| DRH Property Services Limited | Real estate | 2014 |
| Driev Leasing Ltd | Administrative & support | 2021 |
| Driev Ltd | Administrative & support | 2021 |
| Drinks District Ltd | Manufacturing | 2025 |
| Drinks on Demand Limited | Information & communication | 2025 |
| Drinks Wholesale Ltd | Wholesale & retail | 2020 |
| Drip and Shine Ltd | Wholesale & retail | 2018 |
| Drive Deal Ltd | Wholesale & retail | 2025 |
| Driveway Diagnostics Ltd | Administrative & support | 2024 |
| Driving Test Asap Ltd | Education | 2024 |
| Driving Test UK Limited | Wholesale & retail | 2016 |
| DRL Construction Ltd | Construction | 2026 |
| Drlizanne Ltd | Health & social care | 2024 |
| Dromm & Bricks Limited | Real estate | 2023 |
| Dromm Healthcare Ltd | Health & social care | 2017 |
| Dromm Limited | Administrative & support | 2011 |
| Dromm Services Ltd | Real estate | 2017 |
| Drone Creative Videos Ltd | Information & communication | 2023 |
| DRS PVT Ltd | Information & communication | 2025 |
| DRY Clean and Laundry Ltd | Other services | 2021 |
| DS Cabling Ltd | Construction | 2002 |
| DSA Direct Ltd | Other services | 2002 |
| Dscover Ltd | Professional & scientific | 2020 |
| Dsdm 78 Ltd | Construction | 2014 |
| DSE10 Ltd | Construction | 2010 |
| DSK Partners LLP | | 2018 |
| DSK Property Services Ltd | Real estate | 2022 |
| Dspra Ltd | Professional & scientific | 2025 |
| DT Nails Ltd | Other services | 2026 |
| Dteck Maintenance & Installation Limited | Other services | 2024 |
| DTT Removals Ltd | Transport & logistics | 2021 |
| Dtta Services Limited | Health & social care | 2024 |
| DU Plessis Property Investments Ltd | Other services | 2018 |
| DUA Ventures Ltd | Hospitality | 2025 |
| Duaa Investment Ltd | Real estate | 2018 |
| Dual Access Scaffolding Ltd | Construction | 2020 |
| Dubai Gallery Limited | Administrative & support | 2026 |
| Dubox Container Lines Ltd | Transport & logistics | 2021 |
| Duchess Place Management Company Limited | Households | 2001 |
| Duck Trading Company Limited | Hospitality | 2018 |
| Ducktail Ltd | Professional & scientific | 2024 |
| Ducon Foods Ltd | Manufacturing | 2022 |
| Dudley Court Management (RTM) Limited | Households | 2009 |
| Duet Dance Limited | Education | 2015 |
| Duever's Support & Services Ltd | Professional & scientific | 2021 |
| Duffells Investments Limited | Wholesale & retail | 2012 |
| Dufon UK Limited | Administrative & support | 2015 |
| Dugard House LLP | | 2017 |
| Dujon Ltd | Financial services | 2021 |
| Duke Logistics Ltd | Transport & logistics | 2021 |
| Duke Street (Bath) Management Company Limited | Households | 2004 |
| Dukes Court Residents Management Limited | Households | 2002 |
| Dulaj Capital Investment Ltd | Real estate | 2026 |
| Dulan Limited | Construction | 2024 |
| Duloe Brook Eaton Socon Limited | Households | 1981 |
| Dulwich Psychotherapy Limited | Real estate | 2016 |
| Dulwich Sharks Sports Club Limited | Administrative & support | 2025 |
| DUM Treat Ltd | Manufacturing | 2020 |
| Dumitrascu Ltd | Administrative & support | 2010 |
| Dunamis Construction Ltd | Construction | 2025 |
| Dunamis Homes Group Ltd | Professional & scientific | 2022 |
| Dunamis Living Ltd | Real estate | 2022 |
| Duncan Place Management Company Limited | Households | 2001 |
| Dundee Court (Wapping) Limited | Households | 2021 |
| Dundori Management Limited | Households | 2008 |
| Dunfield and Mead Ltd | Hospitality | 2013 |
| Dunirose Ltd | Health & social care | 2015 |
| Dunston High Heaton Limited | Information & communication | 2019 |
| DUO Masters Saloon Ltd | Other services | 2025 |
| Duomax Traders Ltd | Wholesale & retail | 2024 |
| Duotree Homes UK Ltd | Construction | 2024 |
| Duran Handyman Ltd | Construction | 2018 |
| Durand Gardens Management Company Limited | Households | 1993 |
| Durant Pest Solutions Ltd | Administrative & support | 2018 |
| Durkn Site Canteen (PR) Limited | Hospitality | 2010 |
| Durmac Limited | Administrative & support | 2014 |
| Dushaj Property Ltd | Real estate | 2024 |
| Dust and Spray Ltd | Other services | 2016 |
| Dutch Circus and Shows Ltd | Arts & recreation | 2021 |
| DV8 Education & Training Community Interest Company | Professional & scientific | 2003 |
| DVH Fitness Limited | Arts & recreation | 2022 |
| DVP Car Sales Ltd | Wholesale & retail | 2020 |
| DVZ Ltd | Real estate | 2020 |
| DW Electrics Ltd | Construction | 2012 |
| DW Sound Ltd | Manufacturing | 2024 |
| DWM Construction Management & Consultancy Services Ltd | Administrative & support | 2016 |
| DWS Enterprise Ltd | Transport & logistics | 2023 |
| DX Solutions Limited | Information & communication | 2000 |
| DXB Scents Ltd | Wholesale & retail | 2026 |
| Dykeco Enterprise Ltd | Health & social care | 2024 |
| Dynamic Care Group Ltd | Health & social care | 2018 |
| Dynamic Cloud Limited | Information & communication | 2020 |
| Dynamic College London Ltd | Education | 2011 |
| Dynamic Reasoning Limited | Professional & scientific | 2005 |
| Dynamics Solutions Ltd | Information & communication | 2026 |
| Dynamite Signs Limited | Professional & scientific | 2019 |
| Dynamyq Limited | Wholesale & retail | 2019 |
| Dynasty Care Services Limited | Health & social care | 2019 |
| Dynasty Care Support Limited | Health & social care | 2026 |