| Demiurge Systems Ltd | Information & communication | 2026 |
| Demon Recruitment and Resourcing Ltd | Administrative & support | 2014 |
| Dempseys Properties Ltd | Hospitality | 2012 |
| Denby Construction Limited | Real estate | 2001 |
| Denden Transport Limited | Transport & logistics | 2024 |
| Dene Heights Management Company Limited | Households | 2007 |
| Denecroft Limited | Information & communication | 2010 |
| Denecy Limited | Professional & scientific | 2017 |
| Deneholm Property Holdings Ltd | Health & social care | 2022 |
| Denewood Court Limited | Households | 1963 |
| Denfra Ltd | Wholesale & retail | 2012 |
| Denham Island Management Limited | Households | 2011 |
| Denhill Properties Limited | Construction | 2010 |
| Denmorris Maintenance Limited | Real estate | 2008 |
| Denmorris Property Limited | Real estate | 2019 |
| Denne Road Management Company Limited | Extraterritorial | 2005 |
| Denning Mews Limited | Households | 2005 |
| Dennison Contractors Ltd | Construction | 2014 |
| Denominum Ltd | Information & communication | 2020 |
| Densor Bookkeeping & Accounting Ltd | Professional & scientific | 2018 |
| Dental Focus Ltd | Information & communication | 2010 |
| Dental Professionals Limited | Other services | 2009 |
| Dental Solution Ltd | Health & social care | 2008 |
| Dentbox Ltd | Wholesale & retail | 2015 |
| Denver's ALL Fruits Ripe Ltd | Hospitality | 2024 |
| Den’S Heating Ltd | Construction | 2025 |
| DEO Volente Properties Limited | Real estate | 2021 |
| Deo's Local Limited | Wholesale & retail | 2015 |
| Deori Technologies Ltd | Information & communication | 2018 |
| Depares Films Limited | Information & communication | 2015 |
| Depenbech Rise (Malpas) Management Company Limited | Households | 2015 |
| Dependex Logistics Limited | Transport & logistics | 2025 |
| Dera Cuisine 2025 Ltd | Hospitality | 2025 |
| Derby & Scarisbrick House RTM Company Ltd | Households | 2010 |
| Derekbuild Ltd | Construction | 2026 |
| Deriggs Limited | Arts & recreation | 2025 |
| Derma Aesthetics by DR SB Ltd | Health & social care | 2020 |
| Derma Matrix Limited | Wholesale & retail | 2025 |
| Dermont Supplies Limited | Wholesale & retail | 2014 |
| Deroche Consultants Ltd | Professional & scientific | 2008 |
| Derry Medical Ltd | Health & social care | 2023 |
| Derumari Ltd | Information & communication | 2022 |
| Derwent Avenue Management Company Limited | Households | 2007 |
| Derwent House (Kingston) Management Company Limited | Households | 2009 |
| Desai Family Limited | Real estate | 2022 |
| Desai Holdings Limited | Households | 2026 |
| Desert Ridge Limited | Extraterritorial | 2005 |
| DESFACT2 Ltd | Hospitality | 2020 |
| Desh Recruitment Ltd | Administrative & support | 2024 |
| Deshi Taste Ltd | Hospitality | 2025 |
| Deshon Limited | Construction | 2020 |
| Desi Closet Ltd | Wholesale & retail | 2025 |
| Desi Deli LDN Ltd | Manufacturing | 2025 |
| Desi Dhaba VEG Express Limited | Hospitality | 2022 |
| Desi Trendz Ltd | Wholesale & retail | 2016 |
| Design 25 Limited | Real estate | 2017 |
| Design and Technical Services Limited | Construction | 2004 |
| Design Blue Limited | Professional & scientific | 1999 |
| Design Brothers Limited | Information & communication | 1996 |
| Design Group 3 LLP | | 2012 |
| Design Unlimited Ltd | Manufacturing | 2011 |
| Designed by Ritu Ltd | Administrative & support | 2013 |
| Designer Chair Covers to Go Limited | Other services | 2012 |
| Designer Depot PH Ltd | Administrative & support | 2020 |
| Designing Data Networks Ltd | Information & communication | 2019 |
| Desire of the Nations Ltd | Other services | 2025 |
| Desire Solutions Ltd | Other services | 2019 |
| Desmack Limited | Education | 2025 |
| Deson Bespoke Products Ltd | Wholesale & retail | 2018 |
| Deson Kitchens Limited | Wholesale & retail | 2015 |
| Dessert Forest Ltd | Hospitality | 2026 |
| Destek Health Ltd | Administrative & support | 2024 |
| Destiny Hair & Beauty | Education | 2015 |
| Destiny Nails and Beauty Ltd | Other services | 2025 |
| Deut Capital Markets Limited | Financial services | 2018 |
| Deux Chevaux ET Charrette Ltd | Wholesale & retail | 2003 |
| Devalter Ltd | Information & communication | 2025 |
| Develop Croydon Forum Community Interest Company | Professional & scientific | 2013 |
| Development Debt Consultancy Limited | Professional & scientific | 2018 |
| Dever General Store Limited | Wholesale & retail | 2020 |
| Device Repair Ltd | Wholesale & retail | 2018 |
| Devices Experts Ltd | Manufacturing | 2023 |
| Devine Enterprises Limited | Wholesale & retail | 2000 |
| Devon Architectural Products Limited | Professional & scientific | 1997 |
| Devon Door Hardware Ltd | Manufacturing | 2022 |
| Devonhall Management Ltd | Real estate | 2001 |
| Devonshire Court (Shirley) RTM Company Limited | Households | 2011 |
| Devonshire Court Freeholders (Shirley) Ltd | Households | 2013 |
| Devonshire Mews Management Company Limited | Households | 2003 |
| Devonshire Place (Prestwich) Limited | Households | 2007 |
| Devopsdays London Conference Limited | Administrative & support | 2022 |
| Devopsdays London Limited | Administrative & support | 2022 |
| Devotion Trading Properties Limited | Construction | 2025 |
| Devsya Ltd | Information & communication | 2016 |
| Devto Studio Ltd | Information & communication | 2022 |
| Dewgate Limited | Wholesale & retail | 2009 |
| Dewpe Perfumes Ltd | Manufacturing | 2025 |
| Dexter House Limited | Administrative & support | 1985 |
| Dexterben Ltd | Administrative & support | 2020 |
| DFL Bankes Limited | Wholesale & retail | 2020 |