| Upper Syke Gardens Management Company Limited | Households | 2007 |
| Upper Woodcote Catering. T/A Lord Roberts on the Green Ltd | Hospitality | 2022 |
| Upsideup Limited | Information & communication | 2009 |
| Upstairs (London) Ltd | Information & communication | 2018 |
| Upstream Seafoods Limited | Wholesale & retail | 1991 |
| Uptime Services Ltd. | Information & communication | 2001 |
| Upton Pines (Wirral) Management Company Limited | Households | 2017 |
| Uptop Services Limited | Health & social care | 2024 |
| Upts Limited | Construction | 2007 |
| Upzilo Ltd | Information & communication | 2025 |
| UR Marketing Consultants Limited | Professional & scientific | 2021 |
| UR Prime Builders Ltd | Construction | 2026 |
| Uraz Limited | Hospitality | 2026 |
| Urban Ceilings and Partitions Limited | Construction | 2012 |
| Urban Fellowship Ministries International CIC | Education | 2024 |
| Urban Maintenance Landscapes Ltd | Administrative & support | 2012 |
| Urban Oak & Co Ltd | Manufacturing | 2026 |
| Urban Piercings Limited | Administrative & support | 2006 |
| Urban Reflective Ltd | Wholesale & retail | 2023 |
| Urban Refurb Limited | Construction | 2010 |
| Urban Resins Ltd | Construction | 2025 |
| Urban Snacks Ltd | Wholesale & retail | 2026 |
| Urban Space Building & Plumbing Ltd | Manufacturing | 2012 |
| Urban Steamlab Limited | Hospitality | 2025 |
| Urban TRT Limited | Health & social care | 2025 |
| Urban Voice UK C.I.C. | Administrative & support | 2026 |
| Urban Vybez Radio Ltd | Information & communication | 2018 |
| Urbania London Ltd | Professional & scientific | 2017 |
| Urfghd Ltd | Manufacturing | 2026 |
| Urhobo House (UPU UK) Limited | Construction | 2025 |
| Urmikrupa Limited | Wholesale & retail | 2022 |
| Urth Cafe UK Ltd | Hospitality | 2025 |
| Ururban Ltd | Wholesale & retail | 2026 |
| Urwaasam Ltd | Hospitality | 2023 |
| Usabacus Educational Services Limited | Education | 2022 |
| User Revolution Consultancy Limited | Professional & scientific | 2024 |
| Ushna Enterprises Ltd | Wholesale & retail | 2023 |
| Usman Global Limited | Wholesale & retail | 2025 |
| Usman-E-Ghani Ltd | Hospitality | 2021 |
| Utilis Associates Limited | Administrative & support | 2010 |
| Utility Dealer Limited | Financial services | 2018 |
| Utility Switchboard Ltd | Other services | 2020 |
| Utopia Codes Limited | Real estate | 2010 |
| Utopia Windows Ltd | Manufacturing | 2004 |
| Uvently Ltd | Information & communication | 2021 |
| Uxbridge Homes Limited | Construction | 2017 |
| UXK Security Group Ltd | Administrative & support | 2024 |
| UYC Academy CIC | Education | 2024 |
| V & B News Limited | Wholesale & retail | 2010 |
| V & J Bar and Restaurant Limited | Hospitality | 2021 |
| V a B Pelican Ltd | Construction | 2015 |
| V H Sisters Ltd | Wholesale & retail | 2008 |
| V J Komar Limited | Wholesale & retail | 2023 |
| V V Cleaning Limited | Other services | 2010 |
| V&B Events Limited | Hospitality | 2023 |
| V&G Garden Inspiration Ltd | Administrative & support | 2022 |
| V&J Housing Ltd | Real estate | 2023 |
| V&P Expertise Ltd | Professional & scientific | 2017 |
| V&S Construction Services Limited | Construction | 2014 |
| V&T Supermarket Limited | Wholesale & retail | 2025 |
| V-K9 Services Ltd | Administrative & support | 2020 |
| V.H. Dhokia & Sons Limited | Wholesale & retail | 2002 |
| V.J Komar Property Ltd | Real estate | 2023 |
| V.Sinkevicius Ltd | Construction | 2025 |
| VA Capital Ltd | Information & communication | 2019 |
| VA96 Ltd | Construction | 2025 |
| Vaani Cash & Carry Limited | Wholesale & retail | 2006 |
| VAG Auto Parts Ltd | Wholesale & retail | 2024 |
| Vaichal Ltd | Information & communication | 2023 |
| Vaico International Ltd | Administrative & support | 2003 |
| Vaikunth PVT Ltd | Real estate | 2023 |
| Vaish Property Management Limited | Construction | 2021 |
| Vaishu Consultancy Limited | Health & social care | 2025 |
| Valaro Ltd | Wholesale & retail | 2025 |
| Valcinn Ltd | Real estate | 2026 |
| Vale Walk (Peterborough) Management Company Limited | Households | 2008 |
| Valeigh Ltd | Extraterritorial | 2024 |
| Valeng Solutions International Ltd | Professional & scientific | 2021 |
| Valentin a Electricians Limited | Construction | 2020 |
| Valentin Cleaners Ltd | Administrative & support | 2025 |
| Valentina CJ Cleaning Ltd | Administrative & support | 2025 |
| Valentina's Recipes Limited | Hospitality | 2021 |
| Valentino's Pizzeria London Limited | Hospitality | 2021 |
| Valery Delivery Limited | Hospitality | 2020 |
| Valinor Investments Limited | Real estate | 2026 |
| Valley Traders Ltd | Hospitality | 2025 |
| Valour Youth and Adult Service CIC | Other services | 2019 |
| Valpee Limited | Wholesale & retail | 2013 |
| Valuenx Ltd | Construction | 2026 |
| Valuing Health Ltd | Health & social care | 2017 |
| Vamika Foods Ltd | Hospitality | 2024 |
| Van Brothers Ltd | Wholesale & retail | 2017 |
| Van Johnsons Property Ltd | Real estate | 2018 |
| Vanara Ltd | Information & communication | 2017 |
| Vandoria Event Catering Ltd | Hospitality | 2026 |
| Vanee Ltd | Real estate | 2024 |
| Vanessa Towers Ltd | Professional & scientific | 2019 |
| Vanguard Consulting Advisory Ltd | Professional & scientific | 2016 |
| Vanguard Early Years Limited | Health & social care | 2026 |
| Vani&Brothers Dryliner Ltd | Construction | 2009 |