| Saffron Jade Ltd | Professional & scientific | 2019 |
| Saffron Streets Ltd | Real estate | 2017 |
| Safi Croydon Ltd | Wholesale & retail | 2024 |
| Safi UK Investment Limited | Real estate | 2017 |
| Safiya Beauty Ltd | Wholesale & retail | 2021 |
| Safth Property Investment Ltd | Real estate | 2026 |
| Safula Trading Limited | Health & social care | 2023 |
| Safuri Services Ltd | Real estate | 2024 |
| Safwan Ecom Ltd | Wholesale & retail | 2024 |
| Safwan M Baig Limited | Hospitality | 2014 |
| SAG Associates Limited | Professional & scientific | 2019 |
| SAG Care Limited | Health & social care | 2019 |
| SAG Community | Education | 2019 |
| SAG Medical Services Limited | Health & social care | 2018 |
| Saga Energy Limited | Professional & scientific | 2021 |
| Saggiomo Luxury Foods Limited | Wholesale & retail | 2006 |
| Saghan Ltd | Hospitality | 2013 |
| Sagitario Ltd | Real estate | 2011 |
| Sahana Limited | Wholesale & retail | 2020 |
| Sahana Surabhi Ltd | Other services | 2014 |
| Sahara Group UK Ltd | Manufacturing | 2021 |
| SAI Commodities Limited | Wholesale & retail | 2007 |
| SAI Consultancy Services Limited | Information & communication | 2024 |
| SAI Consulting Ltd | Professional & scientific | 2011 |
| SAI Croydon Autos Ltd | Manufacturing | 2015 |
| SAI Food Village Ltd | Manufacturing | 2025 |
| SAI Holdco Limited | Financial services | 2025 |
| SAI Properties Management Ltd | Real estate | 2022 |
| SAI Tech Services Limited | Information & communication | 2024 |
| SAI Vivekanantha Ltd | Other services | 2024 |
| Saideep Healthcare Company Limited | Health & social care | 2015 |
| Saidhanya Ltd | Health & social care | 2020 |
| Saied Nasserzadeh Services Limited | Transport & logistics | 2019 |
| Saigon Blue Limited | Hospitality | 2023 |
| Sailing Barge Cabby Limited | Transport & logistics | 2021 |
| Sailink International Ltd | Wholesale & retail | 2023 |
| Sailplan Limited | Extraterritorial | 2004 |
| Saint Barnabas Close Maintenance Limited | Households | 1969 |
| Saint Cullinan Ltd | Administrative & support | 2023 |
| Saint Judah UK Limited | Wholesale & retail | 2025 |
| Saint Katerina Limited | Hospitality | 2026 |
| Saint Marina Limited | Real estate | 2025 |
| Saint Moses Property Investment Ltd | Real estate | 2021 |
| Saint Pancras Chapel Ltd | Hospitality | 2016 |
| Saint Saviours Lodge Ltd | Real estate | 2018 |
| Saints Hill (NO.1) Management Company Limited | Real estate | 2017 |
| Saintsweb Ltd | Information & communication | 2008 |
| Sainuclear Limited | Manufacturing | 2026 |
| Sais Global Group Ltd | Agriculture & fishing | 2020 |
| Saivishak Ltd | Real estate | 2025 |
| Sajed Traders Ltd | Wholesale & retail | 2022 |
| Sajid and Shazrah Limited | Wholesale & retail | 2020 |
| Sajid Family Investments Limited | Real estate | 2025 |
| Sajjpal Freight & Transit Ltd | Transport & logistics | 2025 |
| Sajo Property Services Ltd | Households | 2026 |
| Sakb Security Services Ltd | Administrative & support | 2026 |
| Saki Asset Limited | Real estate | 2026 |
| Sakimura Architecture Studio Ltd | Professional & scientific | 2022 |
| Sakthi Stores Ltd | Wholesale & retail | 2024 |
| Sakthis Recruitment Limited | Administrative & support | 2024 |
| Sakura Sushi Delivery Limited | Hospitality | 2022 |
| SAL BOB Ltd | Wholesale & retail | 2026 |
| Salas Energy Limited | Construction | 2025 |
| Salderman & Partners Ltd | Financial services | 2016 |
| Saleha Properties Ltd | Real estate | 2017 |
| Salehzoi Ltd | Wholesale & retail | 2023 |
| Sales Expand Ltd | Professional & scientific | 2017 |
| Salesiani Limited | Real estate | 2021 |
| Salesify Ltd | Wholesale & retail | 2024 |
| Salisbury Avenue, Barking Management Company Limited | Households | 1997 |
| Salisbury Place Management Limited | Households | 1988 |
| Sallykidscare Ltd | Health & social care | 2022 |
| Salma Mayer Consulting Limited | Administrative & support | 2009 |
| Salmac Solution UK Limited | Wholesale & retail | 2020 |
| Salome and Celeste Limited | Manufacturing | 2023 |
| Salt Happy Living Limited | Real estate | 2017 |
| Salt Kettle Restaurants Ltd | Hospitality | 2019 |
| Salt Learning Solutions Limited | Education | 2024 |
| Salt Solutions Ltd | Information & communication | 2010 |
| Salter Road (Surrey Docks) Management Company Limited | Real estate | 2015 |
| Salters Lane Management Company Limited | Households | 2003 |
| Saltinbocca Ltd | Hospitality | 2025 |
| Saltpond Services Limited | Other services | 2020 |
| Saltville Limited | Households | 1981 |
| Salty Sea Lass Limited | Other services | 2018 |
| Salvador Design Limited | Professional & scientific | 2007 |
| Salvatore Sacha Morgese Ltd | Information & communication | 2021 |
| Salway Hill Estates (Edenbridge) Limited | Construction | 1959 |
| Salway Hill Estates Limited | Construction | 1959 |
| SAM and VIC Properties Limited | Real estate | 2025 |
| SAM Consultancy (UK) Limited | Extraterritorial | 2006 |
| SAM Kamara Ltd | Real estate | 2017 |
| SAM Mobiles & Vapes Ltd | Wholesale & retail | 2022 |
| SAM Motors Limited | Wholesale & retail | 2009 |
| SAM Properties Management Limited | Real estate | 2025 |
| SAM Yardley Counselling Ltd | Health & social care | 2026 |
| Sam's 1991 Limited | Hospitality | 2024 |
| Sama Eleven Ltd | Information & communication | 2022 |
| Sama Enterprises Limited | Real estate | 2000 |
| Samed Consultancy Ltd | Real estate | 2014 |