| Delma Consulting Limited | Information & communication | 2016 |
| Dempster House Residents Management Company Limited | Households | 1992 |
| Deneb Investments UK Limited | Financial services | 2022 |
| Design in Colour Ltd | Information & communication | 2022 |
| Destar Limited | Information & communication | 2000 |
| Developments in Design Ltd | Construction | 2007 |
| Dexterous Developments Limited | Real estate | 2021 |
| Dhillon & Brar Investments Ltd | Real estate | 2024 |
| Dial House Hotel Limited | Hospitality | 1994 |
| Digivox Ltd | Professional & scientific | 2006 |
| Disconsulting IT Limited | Information & communication | 2005 |
| Ditoma Estate Limited | Real estate | 2016 |
| Ditoma Limited | Information & communication | 2013 |
| DJO Services Limited | Professional & scientific | 1998 |
| DLT Consult Limited | Professional & scientific | 2025 |
| DMG Fortex Limited | Construction | 2025 |
| DMI Vistan Global Limited | Manufacturing | 2025 |
| DNC Studio Ltd | Arts & recreation | 2005 |
| Docc Ltd | Construction | 2022 |
| Dochani Ltd | Professional & scientific | 2013 |
| Domestique Ltd. | Administrative & support | 2005 |
| Doodles Cards, Gifts & Balloons Ltd | Wholesale & retail | 2023 |
| Douglas Flight Training Ltd | Education | 2014 |
| Draffin Associates Limited | Professional & scientific | 2003 |
| Dragon Designs Ltd | Professional & scientific | 2020 |
| Dreamkatcha Ltd | Information & communication | 2013 |
| Dreamspace Media Ltd | Manufacturing | 2015 |
| Drip Swim Ltd | Construction | 2014 |
| DSB Consultancy Ltd | Professional & scientific | 2019 |
| DSH Automation Ltd | Manufacturing | 2019 |
| Dsp-Authentic Limited | Professional & scientific | 2022 |
| DTN Performance Ltd | Real estate | 2003 |
| Dual-Inq Ltd | Professional & scientific | 2026 |
| Dubhlinn Property Limited | Real estate | 2018 |
| Duffy Residential Property Ltd | Real estate | 2025 |
| Durrants Accountants Limited | Professional & scientific | 2013 |
| EA & EA Naughton Limited | Extraterritorial | 2023 |
| Eadie & George Design Ltd | Professional & scientific | 2025 |
| Eagle 2020 Limited | Extraterritorial | 2020 |
| Eagle Advisers Limited | Professional & scientific | 2025 |
| Ebodhi Ltd | Information & communication | 2014 |
| Eccountancy Limited | Professional & scientific | 2009 |
| Eco World Energy Ltd | Construction | 2025 |
| Ecoshine Cleaning&Maintenance Ltd | Administrative & support | 2024 |
| Educational Explorers Film Co.Limited | Information & communication | 1957 |
| Educational Explorers Limited | Information & communication | 1960 |
| Educational Solutions (U.K.) Limited | Wholesale & retail | 1954 |
| Edwood Carpentry & Construction Ltd | Construction | 2023 |
| Elands Court Management Company Limited | Households | 2004 |
| Elderly Accommodation Counsel | Health & social care | 1985 |
| Electronics 2000 Limited | Wholesale & retail | 1983 |
| Elevate Marketing Solutions Limited | Professional & scientific | 2022 |
| Elite Preparation Centre Limited | Education | 2024 |
| Ellie Fitzgerald H&B Ltd | Other services | 2023 |
| Elsburys FX Limited | Administrative & support | 2026 |
| Elsburys Ltd | Professional & scientific | 2003 |
| Emdivysol Healthcare Services UK Limited | Health & social care | 2015 |
| Emergencypsych Limited | Health & social care | 2019 |
| Employment Law People Specialist Consultancy Limited | Administrative & support | 2026 |
| Empowering Strategic Performance Limited | Administrative & support | 2007 |
| EN Avant Limited | Professional & scientific | 2020 |
| Engage Brain Limited | Professional & scientific | 2006 |
| Engineering Project Designs Ltd | Other services | 2011 |
| ENI Gates Limited | Health & social care | 2020 |
| Enki Consulting Ltd | Administrative & support | 2016 |
| Enlighten Limited | Professional & scientific | 2003 |
| Enterprise Content Consultants Ltd | Information & communication | 2024 |
| Entertax Ltd | Professional & scientific | 2016 |
| Environmental Specialist Sustainable Dredging Solutions Ltd | Construction | 2024 |
| Envirotech Insight Ltd | Wholesale & retail | 2026 |
| Ep.Psych Ltd | Health & social care | 2023 |
| Equimind Ltd | Arts & recreation | 2016 |
| Esaren International Ltd | Financial services | 2016 |
| ET Devec Ltd | Real estate | 2023 |
| ET Planning Ltd | Professional & scientific | 2017 |
| Etbt Ltd | Financial services | 2022 |
| Etiam Insights Ltd | Professional & scientific | 2018 |
| Eunus Consulting Limited | Information & communication | 2014 |
| Euphoric Internet Consulting Limited | Information & communication | 2003 |
| Euro IT Group Limited | Information & communication | 2014 |
| Euro Surfacing Contractors Limited | Construction | 2007 |
| Eurograde Plant Limited | Manufacturing | 1972 |
| Evolution Tech Ltd | Information & communication | 2018 |
| Evolv Energy Markets Limited | Professional & scientific | 2017 |
| Evoque BMS Ltd | Construction | 2016 |
| EXO Carriers Ltd | Transport & logistics | 2025 |
| Expert Dynamics Limited | Information & communication | 2011 |
| Extotec Ltd | Professional & scientific | 2021 |
| Faded Academy Ltd | Education | 2021 |
| Faded ERG Ltd | Other services | 2025 |
| Faded NRG Ltd | Other services | 2023 |
| Faded Products Ltd | Wholesale & retail | 2021 |
| Faded Serg Limited | Other services | 2024 |
| Faded WRG Ltd | Other services | 2023 |
| Fairmont Landscapes Ltd | Administrative & support | 2025 |
| Fairmont Solutions UK Ltd | Wholesale & retail | 2023 |
| Fairwey Consulting Limited | Professional & scientific | 2022 |
| Falcon Aviation Limited | Other services | 1991 |
| Falcon Glass & Stone Ltd | Manufacturing | 2024 |
| Fantrade Ltd | Wholesale & retail | 2020 |