| Mission Stone Properties Limited | Construction | 2024 |
| Mitchell Homes Limited | Real estate | 2001 |
| Miza Services Ltd | Agriculture & fishing | 2025 |
| MJ & a Engineering Limited | Professional & scientific | 2019 |
| MJ Airport Associates Limited | Professional & scientific | 2014 |
| MJ Dent Ltd | Health & social care | 2018 |
| MJ MAP Consulting Ltd | Administrative & support | 2015 |
| MJF Construction Ltd | Construction | 2025 |
| Mjgw Limited | Financial services | 2013 |
| Mjhow Ltd | Other services | 2023 |
| MJJ Spark Ltd | Professional & scientific | 2026 |
| MJP Building Ltd | Construction | 2018 |
| MJP Lettings Limited | Real estate | 2020 |
| MJS Dilapidations & Repair Limited | Construction | 2013 |
| MJW Aesthetic Limited | Education | 2023 |
| MKS Instruments Holdings Ltd | Other services | 2013 |
| MKS Instruments UK Limited | Manufacturing | 2007 |
| MKS Spectra Holdings Limited | Manufacturing | 1987 |
| MLK Solutions Ltd | Information & communication | 2025 |
| Mlmhg Ltd | Real estate | 2019 |
| MLS Financial Services Ltd | Financial services | 2019 |
| MM Domestic Cleaning (Crewe) Ltd | Administrative & support | 2017 |
| MM Student Accommodation Cleaning Ltd | Administrative & support | 2021 |
| MMS Barber Ltd | Other services | 2026 |
| MN Medical Services Ltd | Health & social care | 2011 |
| MNK Rendering Ltd | Construction | 2022 |
| Mobat Ventures Limited | Transport & logistics | 2018 |
| Mobby Lets Ltd | Real estate | 2026 |
| Mobile Vets Crewe Limited | Professional & scientific | 2020 |
| Mobinet Ltd | Information & communication | 2023 |
| Modcon Projects Limited | Construction | 2025 |
| Modo Campers Ltd | Manufacturing | 2025 |
| MODULE8 Ltd | Professional & scientific | 2010 |
| Modus AV Ltd | Administrative & support | 2015 |
| Moficas Ltd | Professional & scientific | 2015 |
| Mokes Catering Service Ltd | Hospitality | 2026 |
| MOL Trans Ltd | Transport & logistics | 2021 |
| Mol's Gold Ltd | Wholesale & retail | 2025 |
| Moloney Property Company Limited | Real estate | 2026 |
| Molyneaux's Property Solutions Ltd | Construction | 2020 |
| Momentia Limited | Financial services | 2019 |
| Mongrel Operating Ltd | Information & communication | 2022 |
| Monkeynights Limited | Hospitality | 2017 |
| Monster Junk Franchise Limited | Water & waste | 2022 |
| Monster Junk Limited | Water & waste | 2021 |
| Montezinos Photography Limited | Professional & scientific | 2023 |
| Moodflik Ltd | Information & communication | 2025 |
| Moor Dairy Ltd | Wholesale & retail | 2023 |
| Moor Productions Limited | Information & communication | 2009 |
| Moorlands Fast Food Ltd | Hospitality | 2024 |
| More BHP Limited | Wholesale & retail | 2014 |
| More Than Evaluzion Ltd | Real estate | 2022 |
| Morenacare Ltd | Health & social care | 2020 |
| Moreno Luxury Travel Ltd | Administrative & support | 2025 |
| Morfeus Limited | Wholesale & retail | 2017 |
| Morning Foods,Limited | Manufacturing | 1942 |
| Morning Glass Media Limited | Administrative & support | 2009 |
| Moro Trans Ltd | Transport & logistics | 2014 |
| Morreys (Holmes Chapel) Limited | Wholesale & retail | 1975 |
| Mosaic Rail Ltd | Professional & scientific | 2017 |
| Moss Bank Lodges (Great Salkeld) Limited | Hospitality | 2018 |
| Moss Commercial Services Ltd | Administrative & support | 2016 |
| Moss Lane Horseshoe Close Crewe Management Company Limited | Households | 2020 |
| Mosswood Hall Farmers Ltd | Agriculture & fishing | 2023 |
| Mosteaca Ltd | Transport & logistics | 2018 |
| MOT Centre (Holmes Chapel) Limited | Wholesale & retail | 2016 |
| Motorhome & Camper Connect Ltd | Wholesale & retail | 2024 |
| Motoriva Ltd | Wholesale & retail | 2019 |
| Mounsey Marketing Limited | Professional & scientific | 2009 |
| Mountain OWL Ltd | Professional & scientific | 2013 |
| Movepool Ltd | Information & communication | 2026 |
| Mowbot Limited | Administrative & support | 2024 |
| Moyrisk Holdings Limited | Financial services | 2021 |
| MP Independent Ltd | Wholesale & retail | 2020 |
| MP Motors Repair Ltd | Wholesale & retail | 2026 |
| MP Transport Solutions Limited | Transport & logistics | 2018 |
| Mpkaye Ltd | Other services | 2018 |
| Mptv Productions Limited | Information & communication | 2021 |
| MQC Merrick Quality Care Limited | Health & social care | 2014 |
| MR Blue Crewe Express Ltd | Wholesale & retail | 2025 |
| MR Car Mats Ltd | Wholesale & retail | 2022 |
| MR Chauffeur Ltd | Transport & logistics | 2017 |
| MRC Trans Services Limited | Transport & logistics | 2017 |
| Mreb Consultancy Limited | Public administration | 2013 |
| MRP Motoring Ltd | Wholesale & retail | 2021 |
| MS Auto Restorations Ltd | Construction | 2026 |
| MS Development Projects Ltd | Construction | 2018 |
| MSA Retail Limited | Wholesale & retail | 2025 |
| MSC Defence Limited | Other services | 2024 |
| MSL Scaffolding Ltd | Construction | 2010 |
| Msvision (UK) Ltd | Professional & scientific | 2005 |
| MT65 Solutions Ltd | Construction | 2019 |
| MTB Boat Safety Solutions Ltd | Manufacturing | 2021 |
| MTC Services Limited | Wholesale & retail | 2004 |
| Much International Trade Co Limited | Wholesale & retail | 2015 |
| MUKTA25SPICE Ltd | Hospitality | 2025 |
| Muktamil Care Ltd | Health & social care | 2024 |
| Mulberry House Properties Limited | Real estate | 2015 |
| Muldoon's Irish Bars Ltd | Hospitality | 2026 |
| Multech Solutions Ltd | Professional & scientific | 2011 |