| OLR Services Ltd | Construction | 2014 |
| OLR Solutions Ltd | Information & communication | 2024 |
| ON Sale Auctions Ltd | Wholesale & retail | 2022 |
| One Hope Project Music Limited | Administrative & support | 2022 |
| Opal Compass Ltd | Financial services | 2023 |
| Opalane Limited | Construction | 2009 |
| Opera Australia Capital Fund UK | Professional & scientific | 2005 |
| Orange Cat Studios Ltd | Information & communication | 2023 |
| Orient West Limited | Professional & scientific | 2009 |
| Outdoor Wooden Garden Furniture Limited | Manufacturing | 2014 |
| Outsource Engineering Services Ltd | Professional & scientific | 2021 |
| Oxenacres Limited | Agriculture & fishing | 2003 |
| P a Wright Limited | Manufacturing | 2002 |
| P D Snell T/A Dairy Farm Services Limited | Manufacturing | 2016 |
| P J Warren Limited | Construction | 2003 |
| Page Concrete & Steel Limited | Manufacturing | 1994 |
| Page Partners LLP | | 2001 |
| Paperchain (South West) Co-Operative Limited | Water & waste | 1990 |
| Paradise Construction Limited | Construction | 2016 |
| Paradise Gould Limited | Construction | 2022 |
| Parele Ltd | Construction | 2022 |
| Parish and Shires Commercial Ltd | Administrative & support | 2016 |
| Parkpine Limited | Professional & scientific | 2013 |
| Partridge Hole Game Ltd | Agriculture & fishing | 2020 |
| Paul a Peters Limited | Extraterritorial | 2017 |
| Paul George Sport Horses Ltd | Agriculture & fishing | 2026 |
| Paul Gregory Associates Ltd | Health & social care | 2015 |
| Paul Hulme Engineering Ltd | Professional & scientific | 2017 |
| Paul Naden Plastering Limited | Construction | 2016 |
| Peach Hayne Chicken Rearing Ltd | Agriculture & fishing | 2003 |
| Pegasus Health, Safety and Environmental Ltd | Professional & scientific | 2024 |
| Penkivel Services Limited | Construction | 2019 |
| Pepper Commercial (Exeter) Limited | Real estate | 2015 |
| Perfect Paws Grooming & Spa Ltd | Other services | 2013 |
| Perpetuem Records Limited | Information & communication | 2009 |
| Peter Jourdan Limited | Education | 2016 |
| Peter Simpson Ltd | Professional & scientific | 2023 |
| Phase Three Management Ltd | Households | 2010 |
| Phil Dellamuro Carpentry and Joinery Limited | Construction | 2003 |
| Phil Hill Plant Hire Ltd | Administrative & support | 2025 |
| Phil Smith Construction Limited | Construction | 2024 |
| Phillips Grant Associates Ltd | Administrative & support | 2016 |
| PHJ Dennis & Sons Limited | Construction | 2022 |
| Phoenix Mason Development Ltd | Real estate | 2023 |
| Phoenix Ortu Ltd | Administrative & support | 2023 |
| Phone & Broadband Ltd | Information & communication | 2007 |
| Phototropic Films Ltd | Professional & scientific | 2023 |
| Pikamath Creative Ltd | Administrative & support | 2023 |
| Pinbrook Mews Management Company Limited | Households | 1979 |
| Pippins PRE School (Crediton) | Education | 2013 |
| PJB Decorating Contractors Limited | Construction | 2012 |
| Planet Play (Crediton) Limited | Arts & recreation | 2022 |
| Planet Play (SW) Limited | Arts & recreation | 2016 |
| Plant Sales (Devon) Limited | Wholesale & retail | 2008 |
| Playlines Trust | Education | 2001 |
| Plus Retail Limited | Manufacturing | 2007 |
| Plymouth Roofing Limited | Construction | 2010 |
| Polar Landscaping Ltd | Administrative & support | 2019 |
| Pool 'N' Spa Services Limited | Manufacturing | 1987 |
| Poppyfield Properties (South West) Limited | Real estate | 2020 |
| Porter Ward Developments Ltd | Construction | 2020 |
| Portiah Limited | Administrative & support | 2020 |
| Prestige Electrical Contractors (SW) Ltd | Construction | 2023 |
| Pretty Little Pastries Limited | Wholesale & retail | 2016 |
| Priorton Venn Ltd | Professional & scientific | 2016 |
| Prispens Limited | Manufacturing | 2017 |
| Prjh Management Consultancy Limited | Information & communication | 2023 |
| Profecto Financial Services Ltd | Professional & scientific | 2020 |
| Proflax Limited | Wholesale & retail | 2016 |
| Promind Care Ltd | Health & social care | 2024 |
| Prosound Solutions (SW) Limited | Administrative & support | 2013 |
| Prostate AID CIC | Manufacturing | 2024 |
| Puddiweeke Ltd | Extraterritorial | 2024 |
| Puddle Duck Pubs Ltd | Hospitality | 2024 |
| Pure Build Devon Limited | Construction | 2024 |
| Pureflow Air Conditioning Limited | Manufacturing | 2022 |
| Purity Boutique Spa Limited | Other services | 2012 |
| Purity Studio Limited | Arts & recreation | 2010 |
| PWS Developments Ltd | Construction | 2024 |
| Pyne Electrical Services Ltd | Construction | 2025 |
| Qtech Applications Limited | Information & communication | 1998 |
| Quality Logistics (South West) Limited | Transport & logistics | 2020 |
| Quay Court (Care Centre) Limited | Health & social care | 1999 |
| Quick & Co (Devon) Ltd | Agriculture & fishing | 2002 |
| Quicks Engineering (SW) Limited | Manufacturing | 2014 |
| R & a Crang Limited | Agriculture & fishing | 2014 |
| R & G Barbers Limited | Other services | 2016 |
| R & L Jewell Transport Limited | Transport & logistics | 2012 |
| R & M Peters Property Ltd | Real estate | 2026 |
| R & R Electrical (South West) Ltd | Construction | 2013 |
| R & V John Optical Supplies Limited | Wholesale & retail | 2014 |
| R Bessant Plumbing & Heating Ltd | Construction | 2011 |
| R D Lifting Limited | Professional & scientific | 2018 |
| R D Toms Plant Hire & Groundworks Ltd | Construction | 2022 |
| R J & a P Stephens Limited | Construction | 2017 |
| R K H Construction Limited | Construction | 2014 |
| R. & M. Peters Limited | Construction | 2003 |
| R.J. Salter and SON Limited | Construction | 2002 |
| R.W.T. Edworthy and Sons Limited | Transport & logistics | 1986 |
| Race & Performance Modification Garage Ltd | Wholesale & retail | 2015 |