| Auto Classics (Global) Ltd | Manufacturing | 2024 |
| Avila Consulting Ltd | Professional & scientific | 2025 |
| Awengrace Ltd | Professional & scientific | 2010 |
| B.A.Hosegood Ltd | Health & social care | 2025 |
| Back to Square One Ltd | Construction | 2025 |
| BAG of Badgers Limited | Information & communication | 2011 |
| Bagoly Ltd | Education | 2008 |
| Banbury Holdings Limited | Real estate | 2022 |
| Bang Bang Boxing Club C.I.C. | Arts & recreation | 2023 |
| Bang Bang Boxing Ltd | Arts & recreation | 2023 |
| Baobab Cafe Limited | Hospitality | 2015 |
| Baobab Deli Ltd | Wholesale & retail | 2026 |
| Baphomet 93 Limited | Information & communication | 2020 |
| Bbuoyant Limited | Wholesale & retail | 2013 |
| BC Training Solutions Ltd | Administrative & support | 2022 |
| Beach Mumma Clothing Ltd | Wholesale & retail | 2026 |
| Bearings South West Engineering Services Limited | Professional & scientific | 2022 |
| Bearings South West Limited | Wholesale & retail | 2016 |
| Beaufort INK Limited | Manufacturing | 2021 |
| Beechdown Farms Limited | Agriculture & fishing | 2002 |
| Beechlea Developers Limited | Construction | 2021 |
| Beechlea Holdings Limited | Financial services | 2015 |
| Beechlea Limited | Agriculture & fishing | 2000 |
| Beer Aplin Limited | Professional & scientific | 1997 |
| Beizhu Electric Appliances Ltd | Manufacturing | 2023 |
| Below Zero Devon Ltd | Manufacturing | 2009 |
| Belstone Consulting Limited | Information & communication | 2025 |
| Benbrit Ltd | Manufacturing | 2017 |
| Benjamin Holloway House Ltd | Health & social care | 2012 |
| Bentley's PUB Company Limited | Hospitality | 2013 |
| Bespoke Rehab Ltd | Health & social care | 2023 |
| BID PCB UK Limited | Professional & scientific | 2016 |
| Bidelphis Limited | Information & communication | 2001 |
| Big Birch Ltd | Professional & scientific | 2002 |
| Bikeworx Limited | Wholesale & retail | 1987 |
| Birch Farm Limited | Agriculture & fishing | 2005 |
| BKS (Devon) Limited | Wholesale & retail | 2010 |
| Black Dog Innovation Management Limited | Professional & scientific | 2014 |
| Black Dog Renewables Ltd | Professional & scientific | 2019 |
| Black Square Design Ltd | Professional & scientific | 2023 |
| Blackdown Stay's Limited | Hospitality | 2023 |
| Blackdown Yard Limited | Agriculture & fishing | 2024 |
| Blanchford (Crediton) Limited | Real estate | 2023 |
| Blanchford Financial Services Limited | Professional & scientific | 2024 |
| Blitz IT Clean Ltd. | Other services | 2018 |
| Bloomos Ltd | Information & communication | 2026 |
| Blue Velvet Aesthetics Ltd | Other services | 2026 |
| Boardwalk Devon Ltd | Administrative & support | 2019 |
| BOB Crooks First Glass Limited | Manufacturing | 2004 |
| Bolham Road Enterprises Ltd | Other services | 2015 |
| Bond Bowls Limited | Wholesale & retail | 2008 |
| Boniface Rise (COB Wall) Management Company Limited | Households | 2009 |
| Bookbag Ltd | Wholesale & retail | 2020 |
| Boroso Ltd | Professional & scientific | 2025 |
| Boughton Technical Services Limited | Professional & scientific | 2008 |
| Bourne From Nature Limited | Construction | 2014 |
| Bourne South West Ltd | Other services | 2024 |
| BOW Recreation Group C.I.C. | Arts & recreation | 2015 |
| Bradbury Consulting Services Limited | Administrative & support | 2025 |
| Break on Through Limited | Other services | 2019 |
| Bright Switch Ltd | Professional & scientific | 2018 |
| Brighter Event Limited | Other services | 2014 |
| Broad Spec (SW) Ltd | Construction | 2023 |
| Broadbridge Properties Ltd | Construction | 2018 |
| Bromhead & Chard Ltd | Professional & scientific | 2016 |
| Broomsmead Surfacing Limited | Construction | 2004 |
| Broxford Consulting Limited | Real estate | 2016 |
| Bruce-Jones Productions Limited | Information & communication | 2024 |
| Bruces Pack Holdings Ltd | Financial services | 2025 |
| Bryant Quality Building Limited | Construction | 2007 |
| Buckhawk Builders Ltd | Construction | 2021 |
| Buckland Timber Limited | Manufacturing | 2013 |
| Buckman Associates Limited | Professional & scientific | 2010 |
| Bunce Group Ltd | Real estate | 2025 |
| Burnell Mechanical Services Limited | Wholesale & retail | 2017 |
| Butlers Intra Ltd | Households | 2022 |
| Bytes Computers Limited | Information & communication | 2020 |
| C & H Ford Farm Ltd | Agriculture & fishing | 2015 |
| C J Steer and SON Limited | Construction | 2003 |
| C Marshall (Europe) Limited | Transport & logistics | 1990 |
| C&R Construction South West Ltd | Construction | 2018 |
| C&V Woods Ltd | Construction | 2025 |
| C.J.Mcmillan Ltd | Manufacturing | 2018 |
| Caelo Limited | Wholesale & retail | 2025 |
| Cafe at Red Lion Yard Limited | Hospitality | 2024 |
| CAP Holdings (Devon) Ltd | Financial services | 2024 |
| Carving Community CIC | Arts & recreation | 2011 |
| Cater Contracts Ltd | Administrative & support | 2022 |
| Caterwest Limited | Wholesale & retail | 2013 |
| Caterwise Limited | Manufacturing | 2026 |
| Catling Creative (Global) Ltd | Professional & scientific | 2017 |
| Catmoon Ltd | Real estate | 2001 |
| Caves to Castles Limited | Other services | 2002 |
| Cavvy Games Ltd | Professional & scientific | 2025 |
| Ccsh Holdings Limited | Financial services | 2023 |
| Centre for Dynamic Soils CIC | Professional & scientific | 2025 |
| Chandni Chowk Limited | Manufacturing | 1997 |
| Chapters Untold Ltd | Information & communication | 2026 |
| Charlie Medical Ltd | Wholesale & retail | 2011 |
| Charlie O'Sullivan Limited | Arts & recreation | 2014 |