| Down to a T Cleaning Services Limited | Administrative & support | 2024 |
| Downend View Escapes Ltd | Hospitality | 2026 |
| Downsman PUB Limited | Hospitality | 2024 |
| Doxie Knots Ltd | Manufacturing | 2022 |
| DP Ductworks Ltd | Manufacturing | 2021 |
| DP Enterprises UK Ltd | Wholesale & retail | 2026 |
| DPC Groundworks Ltd | Construction | 2021 |
| DPF Interiors Limited | Construction | 2018 |
| DPS UK Pension Company Limited | Administrative & support | 2021 |
| DR a ALI Ltd | Health & social care | 2024 |
| DR Hendrik Freeke Ltd | Health & social care | 2023 |
| DR Media Group Ltd | Professional & scientific | 2026 |
| DR Prepper Ltd | Information & communication | 2026 |
| DR Ramin Torkizadeh Ltd | Health & social care | 2025 |
| Dragnev Ltd | Transport & logistics | 2018 |
| Dragon 9 Limited | Wholesale & retail | 2024 |
| Dragun General Renovation Ltd | Construction | 2018 |
| Drainage&Plumbing Ltd | Water & waste | 2023 |
| Draught and Bite Limited | Hospitality | 2025 |
| Drayton Advisors Limited | Professional & scientific | 2020 |
| Dre's Anatomy Ltd | Other services | 2024 |
| Dream & Travel Ltd | Administrative & support | 2025 |
| Dream Weaver AI Limited | Information & communication | 2025 |
| Dreams International Limited | Wholesale & retail | 2015 |
| Dreamscape Decorator Ltd | Construction | 2025 |
| DRG Construct Ltd | Construction | 2019 |
| Drifter's Super Whip Ltd | Hospitality | 2023 |
| Drifters Whippy Ltd | Hospitality | 2025 |
| Driftshield AI Ltd | Information & communication | 2024 |
| Drivehive Cars Ltd | Wholesale & retail | 2025 |
| Driver With Passion Ltd | Transport & logistics | 2021 |
| Drivevest Real Estate Limited | Financial services | 2025 |
| Driveway View Ltd | Professional & scientific | 2023 |
| DRL Tech Limited | Information & communication | 2022 |
| Droneify Ltd | Extraterritorial | 2022 |
| Drs.Mess Ltd | Health & social care | 2013 |
| Drzl Ltd | Manufacturing | 2025 |
| DS Autowerks Limited | Wholesale & retail | 2015 |
| DSA Motors Ltd | Transport & logistics | 2025 |
| DSB Accountancy Ltd | Professional & scientific | 2024 |
| DSJ Assets Holding Ltd | Real estate | 2020 |
| DSJ Retail Ltd | Wholesale & retail | 2016 |
| DSK (BSC) Consultancy Ltd | Professional & scientific | 2019 |
| DSK Prime Solutions Ltd | Administrative & support | 2020 |
| DSM Accounting Ltd | Professional & scientific | 2014 |
| DSM Commodities Limited | Financial services | 2025 |
| DSN Promotions Ltd | Other services | 2014 |
| DSP & Company Investments Ltd | Financial services | 2019 |
| DSR Engineers Ltd | Professional & scientific | 2026 |
| DSR Wellbeing Ltd | Administrative & support | 2026 |
| Dsws Support Services Ltd | Wholesale & retail | 2017 |
| DT Plumbing and Building Limited | Construction | 2026 |
| Dtptypes Limited | Information & communication | 1990 |
| Dtruth Limited | Information & communication | 2022 |
| DTS Homes Limited | Real estate | 2020 |
| DTS Scaffolding Ltd | Construction | 2024 |
| Dual Services Ltd | Other services | 2017 |
| Dualdice Limited | Households | 2024 |
| Dubai Shawarma and BBQ Ltd | Hospitality | 2025 |
| Dubai Shawarma and Grill Ltd | Hospitality | 2025 |
| Duckfish Theatre Limited | Arts & recreation | 2019 |
| Ductclean (UK) Limited | Construction | 1998 |
| Dudley Industries Limited | Manufacturing | 1942 |
| Dukesfield Properties Limited | Real estate | 1996 |
| Duman 1974 Limited | Hospitality | 2024 |
| Duman Pizza & Grill Limited | Hospitality | 2026 |
| Dumbledore Dental Care Limited | Health & social care | 2007 |
| Duncan & Grove Group Limited | Financial services | 2022 |
| Duncan & Grove International Ltd | Manufacturing | 2022 |
| Duncan & Grove Ltd | Construction | 2015 |
| DUO Delivers Limited | Extraterritorial | 2016 |
| Dustsweep Repairs Limited | Manufacturing | 2012 |
| DW Construction & Design Ltd | Construction | 2021 |
| Dwealth Healthcare Limited | Wholesale & retail | 2020 |
| DXB Auto Investments Limited | Financial services | 2024 |
| DXB Automotive Property Limited | Real estate | 2025 |
| DXB Automotive Retail Limited | Wholesale & retail | 2025 |
| Dylocon Limited | Information & communication | 2025 |
| Dynamic Viewpoint Healthcare Limited | Health & social care | 2022 |
| Dynast Associates Limited | Wholesale & retail | 2025 |
| Dzautomotive Limited | Wholesale & retail | 2026 |
| Dzzh Service Ltd | Wholesale & retail | 2025 |
| E & a Enterprises Ltd | Wholesale & retail | 2012 |
| E & B Group Limited | Construction | 1993 |
| E a Sher Ltd | Financial services | 2023 |
| E G Brothers Limited | Wholesale & retail | 2025 |
| E H Business Services Ltd | Administrative & support | 2025 |
| E J Becket Limited | Construction | 2012 |
| E K Davis Ltd | Arts & recreation | 2026 |
| E Kett Services Ltd | Administrative & support | 2017 |
| E W Education Ltd | Wholesale & retail | 2012 |
| E&G Decorating Ltd | Construction | 2016 |
| E&M Sunshine Ltd | Wholesale & retail | 2020 |
| E-Learn Healthcare Ltd | Education | 2016 |
| E-Mech Entertainment Engineering Ltd | Arts & recreation | 2005 |
| E-Quick Services Ltd | Construction | 2019 |
| E.G.Powerflush Ltd | Construction | 2013 |
| E124 Ltd | Real estate | 2024 |
| E139 Ltd | Administrative & support | 2025 |
| EAB Finishing Limited | Construction | 2015 |