| David East Farriers Ltd | Professional & scientific | 2011 |
| David GEO Ltd | Transport & logistics | 2015 |
| David Rutland & Co Limited | Construction | 2010 |
| David Such Osteopathy Ltd | Health & social care | 2019 |
| Davidex Limited | Transport & logistics | 2025 |
| Davidson Pre-School Ltd | Education | 2022 |
| Davies Property Maintenance Ltd | Construction | 2010 |
| Davis Industrial Plastics Limited | Wholesale & retail | 1986 |
| Davmir Services Ltd | Transport & logistics | 2021 |
| Davol International Limited | Manufacturing | 1963 |
| Dawks of London Ltd | Information & communication | 2023 |
| Day Associates Limited | Professional & scientific | 2011 |
| Daybrook Interiors Ltd | Construction | 2025 |
| Daydream Cleaning Ltd | Administrative & support | 2020 |
| Days Accident Repair Limited | Wholesale & retail | 2006 |
| DB Biomedical Ltd | Wholesale & retail | 2024 |
| DB Survey Solutions Ltd | Construction | 2011 |
| DB Wealth Planning & Preservation Limited | Other services | 2015 |
| DBL (Sussex) Limited | Wholesale & retail | 2001 |
| DBL Sussex Holdings Ltd | Financial services | 2020 |
| DBL Sussex Property Ltd | Real estate | 2021 |
| DBM Ltd | Hospitality | 2025 |
| DBM Property Consultants Limited | Construction | 2020 |
| DCN Solutions Ltd | Information & communication | 2019 |
| Dcuk (FM) Limited | Extraterritorial | 2015 |
| Dcukfm Holdings Limited | Financial services | 2020 |
| DD Data Consulting Limited | Administrative & support | 2026 |
| DE Technical Services Ltd | Manufacturing | 2018 |
| Deal Beyond Ltd | Wholesale & retail | 2022 |
| Deal Flow Ltd | Information & communication | 2026 |
| Deanbrook Dental Care Limited | Health & social care | 2012 |
| Deanland Airfield LLP | | 2003 |
| Deanos Electrical Ltd | Construction | 2018 |
| Debunx Limited | Financial services | 2026 |
| Deccan Cuisine Ltd | Hospitality | 2025 |
| Declan Oregan Limited | Information & communication | 2013 |
| Declutter Unpack Organise Ltd | Other services | 2024 |
| Decotrend Limited | Wholesale & retail | 2018 |
| Deducto Limited | Information & communication | 2025 |
| Deep Clean Car Wash Ltd | Professional & scientific | 2022 |
| Deep Green Ventures Limited | Professional & scientific | 2024 |
| Deepsocial Ltd | Information & communication | 2019 |
| Deeptechhub Ltd | Information & communication | 2026 |
| Deerhurst Park Management Company Limited | Households | 2006 |
| Defend Pro Security Ltd | Administrative & support | 2024 |
| Defib Experts Ltd | Wholesale & retail | 2024 |
| Define Beauty Services Ltd | Other services | 2020 |
| Defined Barber Parlour Ltd | Other services | 2024 |
| Defining Digital Limited | Information & communication | 2010 |
| Definitive PSA Ltd | Administrative & support | 2006 |
| Degussa Knottingley Limited | Manufacturing | 1955 |
| DEH Electrics Limited | Construction | 2016 |
| DEH IT Ltd | Information & communication | 2013 |
| Deja Music Ltd | Information & communication | 2025 |
| Delabere Limited | Real estate | 2005 |
| Delightful Cafe Limited | Hospitality | 2026 |
| Deliver IT Online Ltd | Hospitality | 2016 |
| DELIVERIES247 Ltd | Transport & logistics | 2022 |
| Delplace Limited | Transport & logistics | 1995 |
| Delplan Limited | Professional & scientific | 2025 |
| Delta Cars Gatwick Ltd | Transport & logistics | 2024 |
| Delta Cctv Overwatch Ltd | Administrative & support | 2026 |
| Delta Home Protection Limited | Administrative & support | 2021 |
| Delta Security Management Limited | Administrative & support | 2018 |
| Deltabit IT Limited | Information & communication | 2007 |
| Deltee Limited | Information & communication | 2013 |
| Delts Gym Limited | Arts & recreation | 2026 |
| Deluxe Detailing Surrey Ltd | Administrative & support | 2021 |
| Denbee Autos Ltd | Wholesale & retail | 2021 |
| Denbo Catering Ltd | Hospitality | 2018 |
| Denby Property Management Ltd | Real estate | 2009 |
| Densitron Limited | Professional & scientific | 2023 |
| Dental Magic (Care) Ltd | Health & social care | 2010 |
| Dentallinked Ltd | Information & communication | 2024 |
| Dentjet Ltd | Health & social care | 2020 |
| Denver Commercial Services Limited | Construction | 2023 |
| Denver Development Services Limited | Construction | 2025 |
| Denver Services Limited | Construction | 2000 |
| Dependable Designs Ltd | Construction | 2016 |
| Dermattract Ltd | Health & social care | 2024 |
| Desh Foods Ltd | Hospitality | 2023 |
| Desi Vibrant Wear Limited | Wholesale & retail | 2024 |
| Design Rocket Ltd | Professional & scientific | 2017 |
| Designated 33 Limited | Financial services | 2018 |
| Designed by Davies Limited | Construction | 2023 |
| Designscapes Landscaping & Groundworks Ltd | Administrative & support | 2023 |
| Despania Ltd | Wholesale & retail | 2019 |
| Destination OZ Limited | Professional & scientific | 2003 |
| Destiny Investment Holdings Limited | Financial services | 2025 |
| Detail Charter Limited | Transport & logistics | 2022 |
| Detailed CARE24 Ltd | Health & social care | 2023 |
| Devastator Ltd | Wholesale & retail | 2018 |
| Developments & Investments 33 Ltd | Construction | 2019 |
| Devere Estate Agencies Limited | Real estate | 2004 |
| Deverlas Solutions Ltd | Information & communication | 2012 |
| Device Analytic Limited | Manufacturing | 2017 |
| Devjour Technologies Limited | Information & communication | 2026 |
| DF Accountants Limited | Professional & scientific | 2020 |
| DG & MG Ltd | Hospitality | 2011 |
| Dgit Consultancy Services Ltd | Professional & scientific | 2025 |