| DJW Auto Design Limited | Other services | 1995 |
| Dmars Enterprise Ltd | Real estate | 2020 |
| DMY Designs Limited | Professional & scientific | 2019 |
| DND Foods Limited | Wholesale & retail | 2003 |
| DP Gears LLP | | 2012 |
| Drink Time Limited | Wholesale & retail | 2025 |
| Drlcc Ltd | Wholesale & retail | 2023 |
| DSM Contracts Ltd | Construction | 2019 |
| Dudley & Stourbridge Pest Control Ltd | Agriculture & fishing | 2017 |
| Dufour Locums Limited | Real estate | 2008 |
| Dunn and Cowe Limited | Extraterritorial | 1981 |
| Dust, Grime & Shine Cleaning Services Ltd | Administrative & support | 2022 |
| DY9 Developments Limited | Construction | 2023 |
| E & R Leisure Limited | Arts & recreation | 2016 |
| E and a Properties (West Midlands) Limited | Real estate | 2020 |
| E and a Steel Services Limited | Manufacturing | 2012 |
| E Cooper Construction Limited | Construction | 2013 |
| E D Nelson Limited | Other services | 2016 |
| E-Lining Limited | Construction | 2025 |
| E. Consulting International Limited | Information & communication | 2000 |
| E.Z Seal Limited | Administrative & support | 2021 |
| Eagles Diner Limited | Hospitality | 2024 |
| Easi-Dec Access Systems Limited | Manufacturing | 1984 |
| EAT Street Gourmet Catering Limited | Hospitality | 2024 |
| Ebex Life Limited | Wholesale & retail | 2025 |
| EBV Global Ltd | Wholesale & retail | 2025 |
| ECL Manufacturing Ltd | Extraterritorial | 2025 |
| Eco Nest Solutions Limited | Construction | 2025 |
| Eco Removal Systems Limited | Manufacturing | 2012 |
| Eco Stock Wholesale Limited | Wholesale & retail | 2025 |
| Edgbaston Property Services Limited | Real estate | 1994 |
| Edge Industrial Supplies Limited | Wholesale & retail | 2022 |
| Edge View Homes Limited | Health & social care | 1999 |
| Edmunds Bros Limited | Construction | 2013 |
| Edmunds Bros Properties Limited | Real estate | 2016 |
| Eggcellent Food Limited | Hospitality | 2023 |
| Eggciting Food Limited | Hospitality | 2025 |
| Eggsternal Catering Limited | Hospitality | 2025 |
| Eggstreme Catering Limited | Hospitality | 2023 |
| EJT Catering Limited | Hospitality | 2026 |
| EL ROI Properties Ltd | Real estate | 2024 |
| Electrical Contracting Limited | Construction | 2018 |
| Electro Discharge Limited | Manufacturing | 1996 |
| Electromech Contracts Limited | Construction | 2005 |
| Elite Auto Hire Ltd | Other services | 2018 |
| Elite Eco Vision Limited | Professional & scientific | 2025 |
| Elite Landscapes & Paving Limited | Construction | 2018 |
| Elite Paving and Construction Limited | Construction | 2005 |
| Elite Physique Body Composition Specialist Ltd | Health & social care | 2016 |
| Elite Stainless Rails Ltd | Manufacturing | 2025 |
| Elite Truck & Trailer Services Limited | Administrative & support | 2020 |
| EMD Catering Ltd | Hospitality | 2024 |
| Emerald Home Care Services Ltd | Health & social care | 2025 |
| Emergency Heating Limited | Other services | 2021 |
| Emiga Consulting Ltd | Professional & scientific | 2025 |
| Emms Developments Limited | Real estate | 2005 |
| Emperor Moves Ltd | Transport & logistics | 2026 |
| Empire Consulting Group Ltd | Professional & scientific | 2025 |
| Energy Education Limited | Education | 2018 |
| Enterprise Grinding Ltd | Manufacturing | 2002 |
| Environmental Tank Solutions Limited | Wholesale & retail | 2024 |
| Esperance Health Care Ltd | Health & social care | 2024 |
| Esthetichem Limited | Wholesale & retail | 2023 |
| Esthetiglow Limited | Other services | 2023 |
| Ethereal Aesthetics Clinic Limited | Other services | 2025 |
| ETHIO24 Property Ltd | Real estate | 2024 |
| Etra Holdings Ltd | Financial services | 2025 |
| European Association of Machine Tool Merchants (British Branch) | Other services | 1991 |
| Eval Maintenance Ltd | Construction | 2025 |
| Evercut Tools Limited | Manufacturing | 1984 |
| Excel Tail Lift Services Limited | Wholesale & retail | 2017 |
| Exclusive Property Development Ltd | Construction | 2025 |
| Express Motor Search Ltd | Wholesale & retail | 2024 |
| Exquisite Taste and Vibez Limited | Hospitality | 2024 |
| External Surface Solutions Ltd | Administrative & support | 2024 |
| Extreme Cooling Ltd | Construction | 2019 |
| FAB Manufacturing Limited | Manufacturing | 2019 |
| Fabcnc Ltd | Manufacturing | 2020 |
| Fabrication Investments Limited | Administrative & support | 2019 |
| Fairfax Windows Limited | Construction | 2021 |
| Fairground Attractions Limited | Arts & recreation | 2017 |
| Falcon Enterprise Midlands Limited | Transport & logistics | 2024 |
| FAM Developments Ltd | Real estate | 2019 |
| Fama Services Ltd | Other services | 2017 |
| Famko Properties Ltd | Real estate | 2025 |
| Farsie Ltd | Real estate | 2021 |
| Fascinans Ltd | Professional & scientific | 2020 |
| Fast Forward HR Ltd | Professional & scientific | 2018 |
| Fastfabs Constructions Limited | Manufacturing | 2004 |
| Fastlane Removals & Shipping Ltd | Transport & logistics | 2024 |
| Fastlane Removals Ltd | Transport & logistics | 2019 |
| Fastline Delivery Ltd | Transport & logistics | 2025 |
| Fastmat Limited | Extraterritorial | 1998 |
| FAT Bears ( Midlands) Limited | Hospitality | 2025 |
| Fence-Rite Limited | Construction | 2014 |
| FH Medics Ltd | Health & social care | 2025 |
| Fiftyfive Wyzed Limited | Real estate | 1998 |
| Find Local Plumbers Limited | Administrative & support | 2025 |
| Fire Equipment Maintenance Limited | Public administration | 2012 |
| Fire-Strut Services Ltd | Wholesale & retail | 2011 |