| RM Brokers Limited | Financial services | 2019 |
| RM Homes and Lifestyle Ltd | Wholesale & retail | 2021 |
| RMB ARC Limited | Administrative & support | 2025 |
| RMK Building Construction Ltd | Construction | 2025 |
| Robin Medical Ltd | Wholesale & retail | 2002 |
| Rock Rise Private Limited | Manufacturing | 2017 |
| Rockettscience Limited | Construction | 2014 |
| Roej Limited | Information & communication | 2021 |
| Rolling on Cycles Ltd | Wholesale & retail | 2009 |
| Romans International Group Limited | Financial services | 2020 |
| Romans International Properties Limited | Real estate | 2020 |
| Romans International Showroom Limited | Real estate | 2025 |
| Romas Hair Salon Limited | Other services | 2024 |
| Romasher Ltd | Households | 2025 |
| Room PR Ltd | Information & communication | 2014 |
| Rosewood Warrior Ltd | Professional & scientific | 2024 |
| ROU Consulting Limited | Administrative & support | 2024 |
| Rowan Psychology Limited | Education | 2022 |
| Roylance Development Ltd | Construction | 2023 |
| RP Build Ltd | Construction | 2021 |
| RPH Homes Limited | Households | 2025 |
| RPS and Co (London) Ltd | Arts & recreation | 2019 |
| RSB Building & Maintenance Limited | Construction | 2011 |
| RSB Ventures Limited | Hospitality | 2023 |
| Ruby Enterprises London Limited | Wholesale & retail | 2022 |
| Ruflaine Management Ltd | Extraterritorial | 2011 |
| Rugged Architecture Limited | Professional & scientific | 2023 |
| Ruwa Limited | Real estate | 2025 |
| Rvwv Lettings Ltd | Real estate | 2020 |
| Ryan Neuro Therapy Centre Limited | Health & social care | 1994 |
| Rysam Limited | Construction | 1995 |
| Ryudo Labs Ltd | Information & communication | 2026 |
| Résh London Ltd | Wholesale & retail | 2025 |
| Résidence Aspira Ltd | Health & social care | 2025 |
| S & Noor Ltd | Real estate | 2022 |
| S a E N Avant Guingamp Limited | Construction | 2022 |
| S and B Hold Co Ltd | Real estate | 2026 |
| S G Carroll Property Services Limited | Real estate | 2018 |
| S Gani Plumbing and Heating Ltd | Construction | 2024 |
| S J Reed Interiors Ltd | Construction | 2013 |
| S&P Bramley Properties Ltd | Real estate | 2019 |
| S.P. Filtration Services Ltd | Wholesale & retail | 2001 |
| Saas Certain Ltd | Information & communication | 2023 |
| Sabauto Limited | Wholesale & retail | 2020 |
| Sabo Trade Limited | Wholesale & retail | 2017 |
| Safe Electrical Services South Ltd. | Construction | 2014 |
| Safe Heat Surrey Limited | Construction | 2024 |
| Safe Steps Care Services Ltd | Health & social care | 2025 |
| SAI Shiv Consulting Limited | Professional & scientific | 2015 |
| SAI Shiv Investment Limited | Real estate | 2021 |
| SAI Shiv Property Group Limited | Real estate | 2024 |
| SAI Shiv Trading Limited | Financial services | 2022 |
| SAI Sudiksha Tech Ltd | Information & communication | 2014 |
| Saja Accountancy Ltd | Professional & scientific | 2012 |
| Sajethaa Limited | Real estate | 2020 |
| Salamo Limited | Administrative & support | 2011 |
| Salford Originals Heavy Street Wear Ltd | Wholesale & retail | 2025 |
| Salter Edwards Limited | Construction | 1911 |
| Saltin Ltd | Construction | 2004 |
| SAM SMT Transport Ltd | Transport & logistics | 2025 |
| Sam's Doggy Daycare Limited | Other services | 2013 |
| Samul Property Ltd | Construction | 2019 |
| Sanchez Holdings Limited | Real estate | 2025 |
| Sanctuary Property Holdings Limited | Real estate | 2026 |
| Sandy Merlin Limited | Real estate | 2023 |
| Sankarlos VEG (Wholesale) Ltd | Wholesale & retail | 2022 |
| Sanova BD Limited | Hospitality | 2025 |
| Sapling Growth Ltd | Professional & scientific | 2020 |
| Saracen Properties Limited | Real estate | 2023 |
| Sarah Marrs Ltd | Information & communication | 2024 |
| Sassw Limited | Wholesale & retail | 2022 |
| SBS IT Ltd | Information & communication | 2010 |
| Scandia Domestic Services Limited | Transport & logistics | 1985 |
| Scarlet GEM Ltd | Administrative & support | 2017 |
| Scarlett on Film Ltd | Information & communication | 2026 |
| Scion Leader Ltd | Professional & scientific | 2024 |
| Scott Inns Limited | Hospitality | 2018 |
| SD Transport Compliance and Solutions Limited | Transport & logistics | 2024 |
| SDG Thirteen Limited | Administrative & support | 2023 |
| Sea Lion Press Ltd | Information & communication | 2016 |
| Search & Research Ltd | Professional & scientific | 2017 |
| Seatosky Limited | Administrative & support | 2022 |
| Seb-Louise Alex Services Ltd | Wholesale & retail | 2011 |
| Second Paxtons Management Company Limited | Households | 1980 |
| Second Sound Ltd | Wholesale & retail | 2024 |
| Sedlescombe Limited | Real estate | 2025 |
| Seed Recruitment Consultants Limited | Administrative & support | 2014 |
| Self-Determination Limited | Information & communication | 2012 |
| Selfify Ltd | Information & communication | 2024 |
| Selly Oak Stays Limited | Real estate | 2025 |
| Selp Group Ltd | Construction | 2019 |
| Serene Tuition Service Ltd | Education | 2023 |
| Serenity Houses Limited | Real estate | 2024 |
| SET2SCREEN Solutions Ltd | Professional & scientific | 2010 |
| Seven Bears Brent Ltd | Real estate | 2018 |
| SG Renova Ltd | Construction | 2025 |
| SGP Building Ltd | Construction | 2018 |
| Shabden Park Residents Limited | Administrative & support | 1978 |
| Shadow Project Clothing Ltd | Wholesale & retail | 2025 |
| Shakespeare IT Services Ltd | Information & communication | 2024 |