| Chairzam Fitness Ltd | Health & social care | 2014 |
| Changing Roles Ltd | Administrative & support | 2013 |
| China Garden (Colne) Ltd | Hospitality | 2023 |
| Chiqsteel Limited | Manufacturing | 2024 |
| CHM Software Limited | Information & communication | 2018 |
| Chosen by Jessica Limited | Wholesale & retail | 2017 |
| Choyce Contractors Limited | Agriculture & fishing | 2000 |
| CHR2 Limited | Transport & logistics | 2025 |
| CHW Surfacing Ltd | Administrative & support | 2002 |
| Clash of the Crooners Ltd | Arts & recreation | 2024 |
| Classic Architecture Limited | Professional & scientific | 2012 |
| Clayton Tanks Ltd | Administrative & support | 2017 |
| Cloud 9 Sales Training & Recruitment Ltd | Administrative & support | 2007 |
| CMH Developments (NW) Ltd | Real estate | 2014 |
| CMH Music Ltd | Arts & recreation | 2017 |
| CMS Live Limited | Information & communication | 2014 |
| CNC 32 Limited | Manufacturing | 2016 |
| CNC Developments Ltd | Real estate | 2021 |
| CNC Dynamics Ltd | Extraterritorial | 2013 |
| CNC Spindles Ltd | Extraterritorial | 2012 |
| CNC Support Limited | Manufacturing | 1997 |
| Coach Lindsay CIC | Health & social care | 2023 |
| Coalition Building Services Ltd | Construction | 2024 |
| Coalition Facilities Management Limited | Real estate | 2018 |
| Coffee Bagel Limited | Wholesale & retail | 2020 |
| Colne and Nelson Rugby Club Limited | Arts & recreation | 2011 |
| Colne BID Limited | Other services | 2018 |
| Colne Blues Society Ltd | Other services | 2022 |
| Colne Carpets Ltd | Wholesale & retail | 2007 |
| Colne Convenience Store Ltd | Wholesale & retail | 2021 |
| Colne Cricket Commercial Ltd | Hospitality | 2025 |
| Colne K9 Ltd | Wholesale & retail | 2024 |
| Colne M.O.T. Centre Limited | Wholesale & retail | 2002 |
| Colne Skyline Builders Ltd | Construction | 2023 |
| Colne Sofas Limited | Manufacturing | 2026 |
| Colne Vehicle Storage Limited | Real estate | 2007 |
| Colnewater Ltd | Manufacturing | 2011 |
| Complete Property Testing Limited | Professional & scientific | 2024 |
| Concept Analysis Design UK Limited | Professional & scientific | 2014 |
| Convenience Stores UK (Colne) Ltd | Wholesale & retail | 2020 |
| Coral Groundworks Limited | Construction | 2022 |
| Cotet Ltd | Information & communication | 2022 |
| Cotton Loom Limited | Wholesale & retail | 2025 |
| County Automotive Limited | Wholesale & retail | 2003 |
| County Brook Limited | Financial services | 2009 |
| CPE Solutions Ltd | Professional & scientific | 2024 |
| Craft Food Holdings Ltd | Manufacturing | 2022 |
| Craven George Rendering & Renovations Ltd | Construction | 2021 |
| Croft Mill UK Limited | Wholesale & retail | 2009 |
| Cruelworld Solutions Ltd | Administrative & support | 2025 |
| Crumb & Play Ltd | Hospitality | 2024 |
| CS Carbon & Cost Consulting Ltd | Professional & scientific | 2024 |
| CT Technical Limited | Professional & scientific | 2023 |
| Cutting Edge Property Maintenance Ltd | Construction | 2024 |
| Cyber Vantage Limited | Information & communication | 2023 |
| D H D Ceilings Limited | Construction | 2002 |
| DA Properties (NW) Limited | Real estate | 2024 |
| Dalton Smith Accountants Ltd | Professional & scientific | 2023 |
| Damp Cure Products Ltd | Wholesale & retail | 2020 |
| David Ingham & SON Limited | Wholesale & retail | 2003 |
| DC Chicken & Pizza Ltd | Hospitality | 2025 |
| DCR Surveying and Estimating Ltd | Construction | 2014 |
| Denis Hartley & SON Limited | Other services | 2003 |
| Dennis Berry Limited | Construction | 1941 |
| Dent Instrumentation (EOT) Limited | Financial services | 2022 |
| Dent Instrumentation Limited | Manufacturing | 1981 |
| Deontology Ltd | Professional & scientific | 2018 |
| Desert Guys Ltd | Hospitality | 2025 |
| Desolate Void Industries Limited | Financial services | 2026 |
| Dgla (Projects) Limited | Professional & scientific | 2020 |
| Digital Soda Limited | Information & communication | 2026 |
| Direct AS Limited | Wholesale & retail | 2019 |
| Dixon Weld Limited | Manufacturing | 2012 |
| DLR Accounting Solutions Limited | Professional & scientific | 2012 |
| DLR Invest Limited | Households | 2023 |
| Dolphin Hand Car Wash (NW) Ltd | Administrative & support | 2025 |
| Dormant Venture Limited | Extraterritorial | 2013 |
| DP Developments NW Ltd | Construction | 2018 |
| Drever Driveways & Landscapes Ltd | Administrative & support | 2026 |
| Drug Safety Limited | Professional & scientific | 2017 |
| Dunbeag Properties Ltd | Real estate | 2023 |
| DW Finance Consulting Ltd | Professional & scientific | 2023 |
| DWS Electrical Ltd | Construction | 2023 |
| Dynamech Engineering Ltd | Professional & scientific | 2024 |
| Dynamic Safety Ltd | Information & communication | 2025 |
| E & W Solutions Ltd | Other services | 2025 |
| E-Minerals Ltd. | Health & social care | 2016 |
| E. a. Foulds Group Limited | Financial services | 2024 |
| E.A. Foulds Limited | Manufacturing | 1933 |
| Eagle Executive Ltd | Transport & logistics | 2022 |
| Easy Clean Limited | Administrative & support | 2015 |
| Easy Clean Management Ltd | Administrative & support | 2026 |
| Eccelentia Travel Ltd | Administrative & support | 2019 |
| Eccleston BED Centre Limited | Wholesale & retail | 2004 |
| Eclipse Sports Ltd | Wholesale & retail | 2019 |
| Ecoceramic Tile Agents Ltd | Wholesale & retail | 2021 |
| ED2 Properties Limited | Real estate | 2022 |
| Edgar Simpson & Sons Limited | Wholesale & retail | 1964 |
| Edison Point Management Limited | Professional & scientific | 2024 |
| Eesa Estates Limited | Real estate | 2025 |