| Encred Limited | Professional & scientific | 2012 |
| Endeavour Moorings Limited | Other services | 2022 |
| Endeavour Tactical Ltd | Manufacturing | 2020 |
| Endeavour Way Limited | Health & social care | 2024 |
| Ending Violence in Essex | Hospitality | 2024 |
| Endo Solutions Ltd | Professional & scientific | 2020 |
| Endstep Global Limited | Wholesale & retail | 2025 |
| Enefer Business Consultants Limited | Information & communication | 2022 |
| Energise Consulting Services Ltd | Professional & scientific | 2019 |
| Energize Consultancy Limited | Professional & scientific | 2016 |
| Energy Corporate Finance Limited | Professional & scientific | 2006 |
| Energy Efficient Heating Limited | Construction | 2007 |
| Energy IMC Ltd | Construction | 2021 |
| Energy Stream Microgeneration Limited | Construction | 2010 |
| Energycare Global Ltd | Construction | 2022 |
| Energypeople Holdings Limited | Financial services | 2017 |
| Energypeople Limited | Professional & scientific | 2001 |
| Energypeople Services Limited | Construction | 2013 |
| Energywyze Limited | Other services | 2023 |
| Energyze Cafe Limited | Hospitality | 2021 |
| Energyze Gym Limited | Arts & recreation | 2017 |
| Enes Memoire Concepts Limited | Wholesale & retail | 2026 |
| Engaging Young Minds Ltd | Education | 2025 |
| Engineer Your Mind Ltd | Education | 2020 |
| English Architectural Limited | Administrative & support | 2011 |
| Enhance JLR Ltd | Arts & recreation | 2022 |
| Enhance Performance Coaching Ltd | Arts & recreation | 2026 |
| Enhance Plymouth Ltd | Health & social care | 2024 |
| Enhance Wellness Ltd | Arts & recreation | 2026 |
| Enhanced Optometry Services Limited | Wholesale & retail | 2013 |
| Enigen UK Limited | Information & communication | 2009 |
| Enigma Research and Consulting Limited | Professional & scientific | 2025 |
| Enlighten Homes Limited | Real estate | 2024 |
| Enlighten Sun Ltd | Wholesale & retail | 2023 |
| Enny's Grill Ltd | Hospitality | 2021 |
| Enroute Detailing Ltd | Manufacturing | 2025 |
| Enroute Private Hire Ltd | Transport & logistics | 2024 |
| Ensequrity Ltd | Information & communication | 2009 |
| Enso Jiujitsu Academy Limited | Arts & recreation | 2022 |
| Ensure Fleet Compliance Ltd | Other services | 2020 |
| Ensure UK Limited | Financial services | 2004 |
| ENT & Maxillofacial Clinics Ltd | Health & social care | 2022 |
| Enterprise Technology Partners Limited | Information & communication | 2010 |
| Enterprise, Trade & Knowledge Group Ltd | Administrative & support | 2011 |
| Enticing Elegance Models Ltd | Arts & recreation | 2024 |
| Entire Recruitment Solutions Limited | Administrative & support | 2010 |
| ENV4M Ltd | Professional & scientific | 2020 |
| Envira Improvements Ltd | Construction | 2024 |
| Enviro Mulch (UK) Limited | Administrative & support | 2004 |
| Enviroarb-Solutions Limited | Agriculture & fishing | 2015 |
| Envisia UK Ltd | Professional & scientific | 2024 |
| Envision Special Projects Ltd | Administrative & support | 2005 |
| Envisioned Properties Ltd | Real estate | 2019 |
| Enzo Hand Car Wash Ltd | Other services | 2021 |
| Enzo Motors Ltd | Wholesale & retail | 2023 |
| Enzo UK Properties Ltd | Real estate | 2025 |
| Eogi Ltd | Wholesale & retail | 2024 |
| EOS Sweeney Limited | Administrative & support | 2023 |
| EPA Holdings Limited | Professional & scientific | 1998 |
| Epanga Group Ltd | Financial services | 2018 |
| Epanga Investments Limited | Financial services | 2020 |
| Epanga Properties Ltd | Real estate | 2018 |
| EPC Certificates Ltd | Professional & scientific | 2021 |
| Ephesey EPM Limited | Professional & scientific | 2011 |
| Epic Hair Design Limited | Other services | 2017 |
| Epicast UK Ltd | Manufacturing | 2024 |
| Epicure Express Limited | Hospitality | 2025 |
| Epidemik Limited | Professional & scientific | 1998 |
| EPM (UK) Ltd | Construction | 2014 |
| Equaliance Ltd | Wholesale & retail | 2024 |
| Equilibrium Education Ltd | Education | 2021 |
| Equilivra Ltd | Public administration | 2025 |
| Equiluxe Ltd | Wholesale & retail | 2020 |
| Equinox Business Partners | | 1999 |
| Equippers Church Essex | Health & social care | 2013 |
| Equity Associates Limited | Financial services | 2021 |
| Equity Development Limited | Financial services | 1991 |
| Equity Holdings Limited | Financial services | 2000 |
| ERA Advisors Limited | Professional & scientific | 2022 |
| Ercolina CML UK Ltd | Extraterritorial | 2013 |
| Eren Kebab Pizza Limited | Hospitality | 2019 |
| Ergon Consulting Limited | Information & communication | 2012 |
| Eric Services Ltd | Health & social care | 2024 |
| Erica Davies Limited | Administrative & support | 2017 |
| Erin Kelly Bridal Ltd | Wholesale & retail | 2019 |
| ERK Care Limited | Public administration | 2023 |
| Ernst Theron Limited | Administrative & support | 2011 |
| Erotica Gardens Ltd | Arts & recreation | 2017 |
| Erotica Portraits Ltd | Administrative & support | 2018 |
| Escalator Productions CIC | Arts & recreation | 2012 |
| Escar (U.K.) Limited | Manufacturing | 1985 |
| Eschaton Ltd | Wholesale & retail | 2019 |
| Esen Food Ltd | Hospitality | 2017 |
| Eshanthsolutions Ltd | Information & communication | 2022 |
| Eshh Property Management and Investment Ltd | Real estate | 2023 |
| Eshopwedrop Ltd | Transport & logistics | 2013 |
| Esion Acoustics Limited | Manufacturing | 2013 |
| Esmaeil Mashadi Limited | Real estate | 2020 |
| Esoft Group Ltd | Transport & logistics | 2023 |
| Esokpunwu Limited | Health & social care | 2019 |