| Sesame Access Solutions Limited | Manufacturing | 2013 |
| SET Fair (Servicing) Ltd | Construction | 2013 |
| Seton Tuning Limited | Wholesale & retail | 2007 |
| Seven Carpentry Limited | Construction | 2017 |
| Seven Contracts Essex Limited | Construction | 2025 |
| Sevensanjuan Ltd | Other services | 2018 |
| Seventeen Twenty-Seven Ltd | Professional & scientific | 2023 |
| Severineswf Ltd | Real estate | 2023 |
| SEW Electrical Ltd | Construction | 2022 |
| Seward Properties Limited | Real estate | 2000 |
| Sewells Construction Group Limited | Professional & scientific | 2019 |
| Sewells Holdings Limited | Administrative & support | 1998 |
| Sewells Reservoir Construction Limited | Mining & quarrying | 1989 |
| Sewfine Exteriors Limited | Administrative & support | 2020 |
| Sewfine Limited | Administrative & support | 2007 |
| Seylon Limited | Professional & scientific | 2016 |
| Seymour Property Investments Limited | Real estate | 2001 |
| SF3 Consultancy Limited | Professional & scientific | 2023 |
| SFC Colchester Essex Ltd | Hospitality | 2019 |
| SFX Bidco Limited | Financial services | 2021 |
| SFX Capital Ltd | Financial services | 2020 |
| SFX Holdings Ltd | Financial services | 2022 |
| SFX Midco Limited | Financial services | 2021 |
| SFX Properties Ltd | Real estate | 2022 |
| SG Bookkeeping Ltd | Professional & scientific | 2018 |
| SG Designs Suffolk Limited | Manufacturing | 2013 |
| SG Interior Design Ltd | Manufacturing | 2016 |
| SG2SAFETY Ltd | Professional & scientific | 2026 |
| Sgal Ltd | Administrative & support | 2006 |
| Sghi Ltd | Construction | 2024 |
| Sgnp Ltd | Health & social care | 2013 |
| Sgpd Ltd | Real estate | 2025 |
| Sgrid Ltd | Extraterritorial | 2017 |
| Sgseb Enterprises Ltd | Wholesale & retail | 2020 |
| SH Consulting Services Ltd | Professional & scientific | 2016 |
| SH Electrical London Ltd | Construction | 2021 |
| SHA Barber Ltd | Other services | 2025 |
| Shaaiz Ltd | Wholesale & retail | 2025 |
| Shabahang Properties and Investments Ltd | Real estate | 2017 |
| Shabak Limited | Real estate | 2023 |
| Shadow Pro Limited | Wholesale & retail | 2023 |
| Shadowgap Design Ltd | Professional & scientific | 2023 |
| Shadows PIT Nursery Limited | Real estate | 2018 |
| Shaikly Motor Company Limited | Wholesale & retail | 2017 |
| Shak Property Ltd | Real estate | 2025 |
| Shake Rattle and Roll Limited | Arts & recreation | 2003 |
| Shake the Canopy Limited | Manufacturing | 2021 |
| Shaken Udder Group Limited | Financial services | 2021 |
| Shaken Udder Limited | Manufacturing | 2007 |
| Shakespeare Developments Limited | Construction | 2000 |
| Shaking BAD Shakes Ltd | Hospitality | 2025 |
| Shalom Education Ltd | Administrative & support | 2017 |
| Shalom Health Ltd | Health & social care | 2024 |
| Shalomicakes Design Limited | Hospitality | 2017 |
| Shamas & Sons Limited | Wholesale & retail | 2021 |
| Shamone IT Consultants Limited | Information & communication | 2013 |
| Shaneen Ltd | Wholesale & retail | 2024 |
| Shanghai Darts Ltd | Wholesale & retail | 2025 |
| Shape Academy Ltd | Education | 2024 |
| Shape Analysis Ltd | Wholesale & retail | 2002 |
| Shape and Colour Limited | Wholesale & retail | 2022 |
| Shape Works Limited | Construction | 2016 |
| Shaped by Sport Ltd | Education | 2022 |
| Sharanya Limited | Information & communication | 2015 |
| Shark Theory Media Ltd | Information & communication | 2024 |
| Sharma Traders Ltd | Wholesale & retail | 2024 |
| Sharps Property Sourcing Ltd | Real estate | 2024 |
| Shawenzi Limited | Real estate | 2025 |
| Shayvs Ltd | Information & communication | 2025 |
| SHE Grows VEG Ltd | Wholesale & retail | 2023 |
| Shearman Property Limited | Construction | 2016 |
| Shedcastle Design and Surveying Ltd | Professional & scientific | 2015 |
| Shedtronics Ltd | Information & communication | 2019 |
| Sheep Digital Ltd | Professional & scientific | 2019 |
| Sheikh Trade Limited | Hospitality | 2024 |
| Shelter Link Ltd | Hospitality | 2025 |
| Shelton Construction Services Ltd | Construction | 2016 |
| Sheppard Brickwork Limited | Construction | 2011 |
| Sherborne Interiors Limited | Information & communication | 2006 |
| Sherchan Property Limited | Real estate | 2023 |
| Sherid Tech Limited | Professional & scientific | 2018 |
| Sheridan Lloyd Recruitment Limited | Administrative & support | 2020 |
| Sherketna Holdings Limited | Financial services | 2025 |
| Sherpa Performance Limited | Arts & recreation | 2025 |
| Sherwood Seven Ltd | Real estate | 2020 |
| SHF Developments Limited | Real estate | 2026 |
| SHI & Co. Ltd | Professional & scientific | 2012 |
| Shieldbsc Ltd | Public administration | 2025 |
| Shielder Go Limited | Information & communication | 2025 |
| Shielsy's Security Solutions Ltd | Administrative & support | 2026 |
| Shift Automotive Ltd | Wholesale & retail | 2018 |
| Shift My Motor Limited | Transport & logistics | 2025 |
| Shifting Sands Expeditions Ltd | Arts & recreation | 2013 |
| Shiloh Delivery Services Ltd | Professional & scientific | 2026 |
| Shimmer Colchester Ltd | Other services | 2018 |
| Shin Anime Ltd | Wholesale & retail | 2024 |
| Shinetech Solutions Limited | Transport & logistics | 2013 |
| Shinetech Solutions London Ltd | Wholesale & retail | 2020 |
| Ship Green CIC | Transport & logistics | 2022 |
| Ship Mews Management Company Limited | Households | 2018 |