| Sandy Lane (Cobham) Management Company Limited | Households | 2000 |
| Sandy Way Property Owners Company Limited | Households | 1979 |
| Santa Monica Investments Limited | Real estate | 2021 |
| Santos Hold Co Limited | Financial services | 2023 |
| Sasd Global Limited | Financial services | 2020 |
| Satori Group Limited | Arts & recreation | 2018 |
| Satsoft Space Ltd | Information & communication | 2023 |
| Savilles DRY Cleaners Ltd | Other services | 2015 |
| Savoir Tax Advisory Ltd | Professional & scientific | 2025 |
| SB Construction Consulting Ltd | Professional & scientific | 2019 |
| SB Events Limited | Administrative & support | 2017 |
| SC Sounds Ltd | Arts & recreation | 2024 |
| Scandi Sisters London Ltd | Professional & scientific | 2019 |
| Scandisisters HUS Ltd | Real estate | 2025 |
| Schiff Homes Freehold Limited | Real estate | 2019 |
| Sdec Consulting Ltd | Administrative & support | 2012 |
| SE8 Consulting Limited | Professional & scientific | 2019 |
| Sebastian Estates International Limited | Real estate | 2011 |
| Sebeya Ltd | Professional & scientific | 2025 |
| SEE YOU Films Ltd | Information & communication | 2026 |
| Seerstone Property Ltd | Real estate | 2023 |
| Seerstone Systems Ltd | Information & communication | 2024 |
| SEH Manager Limited | Construction | 2009 |
| SEH Nominee Limited | Real estate | 2009 |
| Seiles Limited | Manufacturing | 2012 |
| Sellix Solutions Ltd | Wholesale & retail | 2024 |
| Selwood Projects Ltd | Construction | 2025 |
| SEN NGT Ltd | Administrative & support | 2025 |
| Sennen International Limited | Professional & scientific | 2016 |
| Sennen Property Limited | Real estate | 2019 |
| Sequoia Residents Company Limited | Real estate | 1999 |
| SES Manager Limited | Financial services | 2011 |
| SES Nominee Limited | Financial services | 2011 |
| Seven Model Management Ltd | Professional & scientific | 2024 |
| Sevenoaks Animal Feeds Limited | Wholesale & retail | 1974 |
| Sfgc Ltd | Construction | 2020 |
| Shadh Asia Limited | Hospitality | 2026 |
| Shaftesbury Developments Limited | Real estate | 2001 |
| Shamblehurst Limited | Extraterritorial | 2016 |
| Shangri-La Studio Limited | Information & communication | 2024 |
| Sharpe Associates Limited | Professional & scientific | 2012 |
| Shearer Promotions Limited | Arts & recreation | 1992 |
| Sheargold Pianos Limited | Wholesale & retail | 1978 |
| Shetland Pony Centre LLP | | 2024 |
| Shetland Pony Club Ltd | Arts & recreation | 2013 |
| Shiells Holdings Ltd | Financial services | 2026 |
| Shiells Property Development Ltd | Construction | 2026 |
| Shiells Property Investments Ltd | Real estate | 2026 |
| Shinchy Limited | Information & communication | 2018 |
| Shinobi Capital Group Ltd | Information & communication | 2023 |
| Shooting in Slovakia Limited | Administrative & support | 2006 |
| Showman Live (Touring) Limited | Professional & scientific | 2023 |
| Showman Live Limited | Professional & scientific | 2020 |
| SI & KI Properties Limited | Real estate | 2014 |
| Sibton Limited | Extraterritorial | 2022 |
| Sichi Consulting LP | | 2017 |
| Siden Mews Management Company Limited | Households | 2022 |
| Sielo Consulting Limited | Information & communication | 2007 |
| Sierra Oaks Limited | Administrative & support | 2017 |
| Silver Oak Homes Limited | Construction | 2015 |
| Silver Swallow Limited | Professional & scientific | 2000 |
| Silvermere Activities Ltd | Arts & recreation | 2025 |
| Silvermere Gymnastics | Education | 2020 |
| Silvermere Gymnastics Academy Limited | Arts & recreation | 2017 |
| Silvermere Softplay Limited | Arts & recreation | 2023 |
| Silverstinger Limited | Wholesale & retail | 2010 |
| Silverstreet Capital LLP | | 2007 |
| Silverstreet I Limited | Financial services | 2023 |
| Silverstreet II Limited | Financial services | 2023 |
| Silverwood Direct Homes Ltd | Real estate | 2024 |
| Silverwood Investment Properties Ltd | Real estate | 2026 |
| Simplesums Ltd | Professional & scientific | 2022 |
| Simpsons Interiors Limited | Wholesale & retail | 1997 |
| Sims Real Estate Investment Ltd | Real estate | 2024 |
| Sincerely Paul Ltd | Administrative & support | 2006 |
| Single Source ICT Ltd | Information & communication | 2014 |
| Sirius Compliance Solutions Ltd | Professional & scientific | 2008 |
| Sirmoor Limited | Information & communication | 2010 |
| Sisters in Arms Mental Wellbeing Ltd | Health & social care | 2025 |
| Sitesecure Limited | Extraterritorial | 1986 |
| Sixthsaint Limited | Wholesale & retail | 2021 |
| Sjey Ltd | Professional & scientific | 2025 |
| SJN Holdings Ltd | Wholesale & retail | 2020 |
| Skinsuit Ltd | Wholesale & retail | 2022 |
| Skjott & Co Ltd | Professional & scientific | 2024 |
| Skye Court Limited | Real estate | 2025 |
| Skypigs Entertainment Limited | Professional & scientific | 2022 |
| SL Rand Psychology Ltd | Education | 2023 |
| Slater Audiology Limited | Wholesale & retail | 2012 |
| Slitherine Limited | Information & communication | 2009 |
| Slitherine Software UK Limited | Wholesale & retail | 2000 |
| Sloane Street Football Ltd | Arts & recreation | 2026 |
| Sloth Clothing Limited | Wholesale & retail | 2019 |
| Slothwear Limited | Wholesale & retail | 2019 |
| Slyfield Farm Management Limited | Real estate | 2016 |
| SM Elite Management Ltd | Real estate | 2022 |
| Small Steps London Ltd | Wholesale & retail | 2018 |
| Smartpath Ltd | Professional & scientific | 2009 |
| SMC GP Limited | Other services | 2025 |
| SMC Hospitality Holdings Limited | Financial services | 2026 |