| Elation Homes Limited | Real estate | 2015 |
| ELE Print Ltd | Manufacturing | 2023 |
| Electract Holdings Limited | Professional & scientific | 2005 |
| Electract Limited | Construction | 1950 |
| Electricare (Domestic) Limited | Professional & scientific | 1984 |
| Electro Management Solutions Limited | Professional & scientific | 2024 |
| Elegant (Properties) Derby Ltd | Real estate | 2017 |
| Elegant Treats Limited | Wholesale & retail | 2025 |
| Elerte UK Limited | Wholesale & retail | 2015 |
| ELEV8 Physiques Ltd | Health & social care | 2025 |
| Elevate Studios DP Ltd | Professional & scientific | 2025 |
| Elite Consultancy Services Limited | Professional & scientific | 2000 |
| Elite ERA Coaching Ltd | Health & social care | 2025 |
| Elite Flooring East Midlands Limited | Wholesale & retail | 2021 |
| Elite Gaming Lounge Limited | Hospitality | 2018 |
| Elite Hair Group Ltd | Other services | 2023 |
| Elite Heating Solutions Ltd | Construction | 2017 |
| Elite Interior Specialists Limited | Construction | 2010 |
| Elite Metal Solutionz Ltd | Administrative & support | 2017 |
| Elite Security 2000 Limited | Construction | 2000 |
| Elizabeth Grace Design Ltd. | Other services | 2014 |
| Ellis Clarke Contracts Ltd | Construction | 2017 |
| Elverstone Large Ltd | Professional & scientific | 2010 |
| Elysian Creativity and Wellbeing Limited | Wholesale & retail | 2016 |
| EM Housing and Maintenance Ltd | Real estate | 2023 |
| EMA Cleaning Ltd | Administrative & support | 2023 |
| Emadel Limited | Other services | 2020 |
| Embark Associates Limited | Administrative & support | 2007 |
| Ember Financial Services Limited | Professional & scientific | 2026 |
| Emergency Response 247 Ltd | Health & social care | 2019 |
| EMF Digital Limited | Information & communication | 2026 |
| EMH Care and Support Limited | Health & social care | 1990 |
| EMH Consult Ltd | Professional & scientific | 2025 |
| EMH Development Company Limited | Construction | 2018 |
| Emms Healthcare Limited | Health & social care | 2018 |
| Emperor's Brewery Ltd. | Manufacturing | 2017 |
| Empower Strength CIC | Arts & recreation | 2025 |
| Empower Vape Limited | Wholesale & retail | 2022 |
| Enabling Developments Ltd | Construction | 2021 |
| Enabling Others Limited | Health & social care | 2020 |
| END State Ltd | Professional & scientific | 2017 |
| Energy on 24 Limited | Manufacturing | 2025 |
| Engineering Design & Supplies Ltd | Manufacturing | 2020 |
| English Oak Homes Limited | Construction | 1981 |
| Enrych | Other services | 2001 |
| Entrust FS Limited | Financial services | 2020 |
| Envire Limited | Construction | 2013 |
| Environer Developments Ltd | Construction | 2024 |
| EP Executive Search LLP | | 2010 |
| Epal UK & Ireland Ltd | Other services | 2004 |
| EPT Services Ltd | Extraterritorial | 2015 |
| Eronsy Express Services Ltd | Transport & logistics | 2026 |
| Eronsy Healthcare Ltd | Health & social care | 2021 |
| Esbeare Site Services Ltd | Professional & scientific | 2024 |
| Escape Coalville Limited | Arts & recreation | 2024 |
| Essential Engineering Solutions Limited | Professional & scientific | 2019 |
| Essex Occupational Health Limited | Health & social care | 2004 |
| Etico Solutions Ltd | Information & communication | 2025 |
| ETM Groundworks Ltd | Construction | 2010 |
| ETS UK Business Ltd | Wholesale & retail | 2018 |
| Etta & Elle Aesthetics Limited | Other services | 2024 |
| Ettrickisson Ltd | Professional & scientific | 2026 |
| Euro Tyres Coalville Limited | Wholesale & retail | 2023 |
| Euro-Projects Contractors Ltd | Administrative & support | 2012 |
| Euro-Projects Group Holdings Ltd | Administrative & support | 2004 |
| Euro-Projects Recruitment Ltd | Administrative & support | 2012 |
| European Supermarket (Coalville) Ltd | Wholesale & retail | 2021 |
| Evans Equestrian Ltd | Agriculture & fishing | 2025 |
| Evered Limited | Professional & scientific | 1954 |
| Evolve Accountants and Business Advisors Ltd | Professional & scientific | 2019 |
| Evolve Business Group Ltd | Financial services | 2020 |
| Evolve Outsourcing Ltd | Professional & scientific | 2009 |
| Exon Race Engines Ltd | Manufacturing | 2010 |
| Expert Road Haulage Ltd | Wholesale & retail | 2019 |
| Expert Weed Solutions Ltd | Administrative & support | 2024 |
| Expozo Holdings Ltd | Wholesale & retail | 2024 |
| Express Road Haulage Ltd | Transport & logistics | 2024 |
| F & L - Lush Cleaning Services Ltd | Administrative & support | 2025 |
| F & P Investments Limited | Professional & scientific | 2006 |
| F K Harwood Limited | Professional & scientific | 2014 |
| Facadedna Ltd | Professional & scientific | 2022 |
| Famity Ltd | Wholesale & retail | 2023 |
| Fandom Coalville Ltd | Transport & logistics | 2022 |
| Farmside Child Day Care Ltd | Education | 2011 |
| Fastest LAP Apparel Ltd | Wholesale & retail | 2023 |
| FCV Grace Dieu FC Limited | Arts & recreation | 2024 |
| Fenix Trading WM Ltd | Wholesale & retail | 2020 |
| Fetra Fencing Systems Limited | Manufacturing | 2024 |
| Fettes & Mason Limited | Manufacturing | 2025 |
| FEW and Found Ltd | Wholesale & retail | 2026 |
| Fibre Trade Ltd | Water & waste | 2023 |
| Fidel and Chocho Ventures Ltd | Professional & scientific | 2022 |
| Fields Housing Services Ltd | Professional & scientific | 2023 |
| Financial Reporting Services (UK) Limited | Professional & scientific | 2015 |
| Fine Mind Psychology Ltd | Education | 2019 |
| Fingensolutions Limited | Professional & scientific | 2025 |
| Fiona Allcoat Ltd | Professional & scientific | 2025 |
| Fire Door Range Ltd | Public administration | 2022 |
| Firebolt Trading Ltd | Financial services | 2025 |
| First Choice International Ltd | Education | 2022 |