| RJC Industrial Safety and Training Ltd | Administrative & support | 2017 |
| RJG Contracting Services Limited | Construction | 2007 |
| RJS Contracts Ltd | Construction | 2023 |
| RKE Engineering Limited | Construction | 2017 |
| Rkvini Limited | Wholesale & retail | 2025 |
| RL Processing Ltd | Manufacturing | 2026 |
| RM Racing Limited | Arts & recreation | 2017 |
| RMS Auto Solutions Ltd | Wholesale & retail | 2019 |
| RNM Property Investments Limited | Construction | 2025 |
| Robert NEE Windows Limited | Construction | 2025 |
| Roccpres Access Limited | Construction | 2018 |
| Rolin Developments Limited | Real estate | 2021 |
| Roll the Dice Cafe Limited | Hospitality | 2023 |
| Roost Estate Agents Ltd | Real estate | 2020 |
| Roost Lettings Limited | Real estate | 2022 |
| Roost Property Services Ltd | Real estate | 2025 |
| RPG Coatings Ltd | Construction | 2025 |
| RR Superstore Ltd | Wholesale & retail | 2023 |
| RS E and I Electrical Limited | Construction | 2021 |
| RT Property Services & Management Limited | Households | 2024 |
| S & R Properties GY Limited | Real estate | 2022 |
| S F Brown Maritime Services Ltd | Transport & logistics | 2022 |
| S H Property Grimsby Limited | Real estate | 2022 |
| S M Building & Construction Limited | Construction | 2011 |
| S&G Payworx Ltd | Other services | 2025 |
| S&L Jewellers Ltd | Wholesale & retail | 2022 |
| S. Foreman Instrument Services Limited | Extraterritorial | 1997 |
| SAB Scaffold Ltd | Construction | 2019 |
| SAC Engineering Consultant Limited | Professional & scientific | 2024 |
| Safeway Scaffolding Services Ltd | Administrative & support | 2007 |
| SAI Harris Ltd | Households | 2024 |
| Salford Candle Company Ltd | Manufacturing | 2024 |
| Salientservices Ltd | Construction | 2009 |
| Sally O'Neill Limited | Health & social care | 2022 |
| Salon 39 Limited | Other services | 2024 |
| Salty Sea Dogs Pet Services Ltd | Other services | 2025 |
| Sam's 1 Barber Ltd | Other services | 2025 |
| Sample Sped GY Limited | Transport & logistics | 2023 |
| Samuel Bottomley Properties Limited | Real estate | 2024 |
| Sassnucks HSE Ltd | Professional & scientific | 2024 |
| Savage's Caistor Limited | Hospitality | 2012 |
| Saxon House Management Company Cleethorpes Limited | Real estate | 2007 |
| Scott Mclean Timber Frame Ltd | Construction | 2018 |
| SDK IT Services Ltd | Extraterritorial | 2018 |
| Sea Health Limited | Manufacturing | 2019 |
| Seahorse Fisheries Limited | Wholesale & retail | 2002 |
| Seaside Cabs Ltd | Transport & logistics | 2025 |
| Seaside Railway Group Ltd | Transport & logistics | 2021 |
| Seaview Street Ltd | Hospitality | 2023 |
| Sebel Consultants Limited | Professional & scientific | 2025 |
| Select Finishing Services Ltd | Construction | 2019 |
| Sensational Experiences Limited | Hospitality | 2025 |
| Serenity Memorials Limited | Other services | 2008 |
| Sevallure Ltd | Wholesale & retail | 2022 |
| SF Home Interiors Ltd | Professional & scientific | 2019 |
| SFC Trading Limited | Wholesale & retail | 2019 |
| SGT Enterprises Ltd | Wholesale & retail | 2024 |
| Shadow Asset Finance Ltd | Financial services | 2016 |
| Shadow Automotive Ltd | Wholesale & retail | 2023 |
| Shadow Properties Ltd | Real estate | 2025 |
| Shadow Service Centre Ltd | Extraterritorial | 2024 |
| Shahram Haji Ltd | Wholesale & retail | 2023 |
| Shameran Limited | Hospitality | 2025 |
| Shanghai Express Ltd | Hospitality | 2020 |
| Shaz Super Market Ltd | Wholesale & retail | 2026 |
| Sheppard Site Services Ltd | Construction | 2024 |
| Sherwood Apartments Limited | Real estate | 2020 |
| Sherwood Sands Limited | Other services | 2022 |
| Shivan Catering Ltd | Hospitality | 2017 |
| Short Fuse Limited | Construction | 2014 |
| Shunar Bangla Limited | Hospitality | 2016 |
| Shutters of Elegance Limited | Manufacturing | 2020 |
| Sibley Hair Ltd | Other services | 2019 |
| Side by Side (Caistor) Limited | Hospitality | 2022 |
| Side by Side Events Limited | Hospitality | 2025 |
| Sidney Sussex Community Group Ltd | Administrative & support | 2017 |
| Signhills Academy Limited | Education | 2011 |
| Silver Lake Investments Limited | Real estate | 2019 |
| Silver Serviced Lettings Limited | Households | 2022 |
| SIM Pro Golf Limited | Arts & recreation | 2021 |
| Simay Organisation Ltd | Hospitality | 2025 |
| Simon Howram Handyman Services Limited | Other services | 2008 |
| Simplifying Cleaning Ltd | Administrative & support | 2021 |
| Simplitech Ltd | Information & communication | 2021 |
| Simpo Ltd | Wholesale & retail | 2018 |
| Simpsons Timber Limited | Wholesale & retail | 2012 |
| Skillsfile Limited | Information & communication | 2025 |
| Skinny Wrists Limited | Wholesale & retail | 2014 |
| SKT Technical Services Limited | Professional & scientific | 2013 |
| Skyline Holiday Homes Limited | Hospitality | 2018 |
| Smart Cool Ltd | Energy | 2019 |
| Smelloway BIN Cleaning Ltd | Administrative & support | 2022 |
| SMG Industrial Solutions Ltd | Construction | 2024 |
| SMH Traffic Solutions Ltd | Construction | 2017 |
| Smith & Brabben Building Services Limited | Construction | 2017 |
| Smth Ltd | Other services | 2023 |
| Snephrue Ltd | Transport & logistics | 2026 |
| Snip-Its Limited | Other services | 2008 |
| SNK Leisure Limited | Hospitality | 2007 |
| Snowden & SON Property Limited | Real estate | 2026 |