| Daynes Demolition Limited | Construction | 1975 |
| DB Welding & Fabrication Ltd | Manufacturing | 2025 |
| Dbtapparel Ltd | Manufacturing | 2024 |
| DC Structures Ltd | Professional & scientific | 2023 |
| DC Studios (Barnsley) Limited | Information & communication | 2022 |
| DCL Estate Agents Ltd | Real estate | 2021 |
| DCP Total Solutions Limited | Information & communication | 2009 |
| Dd's Care Limited | Health & social care | 2023 |
| DDC Plant & Commercial Sales Ltd | Construction | 2022 |
| Dean Property Ltd | Real estate | 2016 |
| Deconstructed Limited | Construction | 2022 |
| DEE Project Consulting Ltd | Professional & scientific | 2012 |
| Deen Foods Ltd | Wholesale & retail | 2026 |
| Deep Retail Limited | Information & communication | 2017 |
| Deer Crescent Ltd | Other services | 2026 |
| Definition Retail Limited | Administrative & support | 2021 |
| Deli & Dine Hospitality Ltd | Hospitality | 2022 |
| Denby Limited | Financial services | 2007 |
| Derwent Property Enhancements Ltd | Construction | 2024 |
| Design Hub Yorkshire Ltd | Manufacturing | 2022 |
| Design Print Repeat Ltd | Manufacturing | 2024 |
| Designtech Fabrications Limited | Manufacturing | 2016 |
| Devon Blue Productions Limited | Information & communication | 2021 |
| Dhillons Estate Agents Limited | Real estate | 2023 |
| DHR Management Limited | Hospitality | 2017 |
| Diamond Nails (Cleckheaton) Ltd | Other services | 2022 |
| Diamond Properties Holdings Limited | Real estate | 2017 |
| Dickinson's Property Services Ltd | Real estate | 2025 |
| Diesel Logic Ltd | Manufacturing | 2025 |
| Dimplx Limited | Financial services | 2020 |
| Direct Structural Detailing Limited | Professional & scientific | 2020 |
| Direct Training Ltd | Health & social care | 2016 |
| Distinctive Dubs Ltd | Wholesale & retail | 2024 |
| Divan BED Superstore Ltd | Wholesale & retail | 2022 |
| DL Roofing & Solar Specialists Limited | Construction | 2020 |
| DMD Design & Marketing Ltd | Financial services | 2020 |
| DOC Imad Ltd | Health & social care | 2013 |
| Door Jewellery London Ltd | Wholesale & retail | 2020 |
| Door Panels by Design Limited | Manufacturing | 2008 |
| Doyle & Doyle Limited | Wholesale & retail | 2016 |
| Doyles Fisheries Ltd | Real estate | 2011 |
| DP York Limited | Hospitality | 2022 |
| DPH (SPV1) Limited | Real estate | 2022 |
| DPH (SPV2) Limited | Real estate | 2022 |
| DPH (SPV3) Limited | Real estate | 2023 |
| Dprop Limited | Real estate | 2018 |
| DR Dolittle Ltd | Other services | 2016 |
| DR MHA Ltd | Health & social care | 2015 |
| Dream Clothing Ltd | Wholesale & retail | 2025 |
| Dream Scene Scenery Ltd | Construction | 2023 |
| Drive Consult Limited | Professional & scientific | 2021 |
| Drury's Projects Limited | Wholesale & retail | 2025 |
| DS Consulting Services Ltd | Professional & scientific | 2025 |
| DT Electrical Installation Ltd | Construction | 2016 |
| DT Fabs Ltd | Manufacturing | 2024 |
| DTA Property Services Limited | Construction | 2025 |
| Ducted Solutions Ltd | Professional & scientific | 2024 |
| Duhosk Properties Limited | Real estate | 2009 |
| Dunne's Driveways & Groundworks Limited | Construction | 2025 |
| Duodetriginta Limited | Financial services | 2024 |
| E & J Haulage Limited | Transport & logistics | 2011 |
| E Service Engineering Ltd | Administrative & support | 2024 |
| E Stand 2017 Ltd | Construction | 2017 |
| E Stockwell Estates Ltd | Real estate | 2025 |
| E.F.C. Consultancy Limited | Real estate | 2002 |
| Easi MUZ Ltd | Administrative & support | 2014 |
| Easingwold Wood Burial | Real estate | 2023 |
| East Rigton Properties Limited | Construction | 1965 |
| Easystands Limited | Manufacturing | 2000 |
| EBB Technology Limited | Professional & scientific | 2017 |
| EBM Health Limited | Professional & scientific | 2023 |
| Ecad/Cam Ltd | Professional & scientific | 2022 |
| ECD Ltd | Education | 2018 |
| Eco Heating Yorkshire Limited | Construction | 2012 |
| Ecommerce Brands Ltd | Wholesale & retail | 2018 |
| Ecxo Ltd | Professional & scientific | 2020 |
| Eden Fine Wines Limited | Wholesale & retail | 2006 |
| Edge Accessories Limited | Wholesale & retail | 2017 |
| Edgylittlepieces Limited | Wholesale & retail | 2019 |
| Edison Motors Ltd | Wholesale & retail | 2026 |
| Edstart South Bradford Limited | Education | 2025 |
| Educate HR Limited | Administrative & support | 2010 |
| Education at JR Ltd | Other services | 2024 |
| EH Lifestyle Limited | Wholesale & retail | 2024 |
| Eighty Twenty Living Limited | Real estate | 2025 |
| EJ Distributors Ltd | Wholesale & retail | 2026 |
| EK Healthcare Services Limited | Health & social care | 2024 |
| EL Solutions Limited | Real estate | 2017 |
| Eldy Ltd | Real estate | 2024 |
| Elegant Homes (Somerset) Limited | Construction | 2009 |
| Elegant Stone Garden & Leisure Limited | Manufacturing | 2007 |
| Elegant Stone Limited | Manufacturing | 1998 |
| Elite Asbestos Solutions Ltd | Construction | 2018 |
| Elite Composite Doors Limited | Other services | 2018 |
| Elite Roofing Specialists (Yorkshire) Ltd | Construction | 2023 |
| Elite Sales Services Limited | Wholesale & retail | 2022 |
| Elite Sport Pathways Ltd | Arts & recreation | 2025 |
| Elite Systems (GB) Limited | Manufacturing | 1991 |
| Elite Upvc (Yorkshire) Limited | Manufacturing | 2025 |
| Elizabeth James Prime Properties Ltd | Real estate | 2019 |