| DU Brother’S Ltd | Hospitality | 2025 |
| Duce Taxation Services Limited | Professional & scientific | 2008 |
| Duckworth and Co Limited | Hospitality | 2026 |
| Duckworth Property Limited | Real estate | 2024 |
| Duckworth Ventures Limited | Hospitality | 2026 |
| Dukinfield Service Centre Limited | Wholesale & retail | 2025 |
| Dun-Walkin Ltd | Administrative & support | 2014 |
| Dunera Limited | Construction | 2011 |
| Dungaree Adventures Ltd | Manufacturing | 2024 |
| Dunya Desserts Ltd | Hospitality | 2025 |
| Duoline Access Ltd | Real estate | 2017 |
| Dupuis Consulting Limited | Administrative & support | 2023 |
| Duratec Plastics Limited | Manufacturing | 2019 |
| Durham Property Maintenance Ltd | Construction | 2016 |
| Durrant Construction Limited | Construction | 2012 |
| Durstock Limited | Construction | 1986 |
| Dussek Campbell Ltd | Professional & scientific | 2013 |
| Duxbury Builders Limited | Construction | 1978 |
| Duxbury Logistics Ltd | Transport & logistics | 2019 |
| Duxbury Mortgages Limited | Financial services | 2017 |
| Duxbury Park DIY Ltd | Wholesale & retail | 2003 |
| Duxbury Tiling Contractors Ltd | Construction | 2025 |
| Dvss Limited | Professional & scientific | 2002 |
| DW Modelling Ltd. | Professional & scientific | 2025 |
| DW Motorsport Limited | Arts & recreation | 2019 |
| DWG (NW) Ltd | Administrative & support | 2010 |
| Dyet Design and Build Ltd | Manufacturing | 2019 |
| Dymphnajane Limited | Wholesale & retail | 2020 |
| Dynamic Agencies Ltd | Wholesale & retail | 2011 |
| Dynamic Distribution Group Ltd | Wholesale & retail | 2024 |
| Dynamic Neurophysiotherapy Limited | Health & social care | 2016 |
| Dynasty Investments SB Limited | Financial services | 2021 |
| Dérive Motorhome Hire Ltd | Administrative & support | 2022 |
| E & a Holdings 2020 Limited | Financial services | 2020 |
| E & F Estates Limited | Real estate | 2025 |
| E - Racing UK Limited | Wholesale & retail | 2023 |
| E B a Electrical Eco Solutions Ltd | Construction | 2022 |
| E H Roofing & Cladding Limited | Construction | 2022 |
| E Lynch Limited | Professional & scientific | 2010 |
| E&C Properties Limited | Real estate | 2017 |
| E&D Designs Limited | Wholesale & retail | 2023 |
| E-Partner Solutions Limited | Information & communication | 2004 |
| E.A.E Logistics Ltd | Transport & logistics | 2026 |
| E3 Building Services Limited | Construction | 2019 |
| E3 Employment Law LLP | | 2012 |
| Eagle Tower Properties Limited | Administrative & support | 2006 |
| Eagleview Properties Limited | Real estate | 2021 |
| Eakin Surgical Limited | Manufacturing | 2000 |
| Earle Group Limited | Wholesale & retail | 2017 |
| Earls Farm Limited | Other services | 2000 |
| Earth Trade Solutions Ltd | Other services | 2022 |
| Easy Care Group Limited | Administrative & support | 2023 |
| Easy Footcare Limited | Health & social care | 2014 |
| Easy Home Lets Ltd | Real estate | 2011 |
| Easy Home Sales Ltd | Real estate | 2013 |
| Easy Web Sites Limited | Information & communication | 2007 |
| Easychemicals Limited | Wholesale & retail | 2004 |
| Easydeal Limited | Wholesale & retail | 2015 |
| Easyplumb Ltd | Construction | 2015 |
| Easytech (NW) Limited | Information & communication | 2019 |
| EAT My Logo Limited | Wholesale & retail | 2014 |
| Eaton Psychotherapy Ltd | Health & social care | 2022 |
| Eaves Lane Discount Store Ltd | Wholesale & retail | 2026 |
| Eazy Kitchen Ltd | Manufacturing | 2020 |
| EB Sports Ltd | Construction | 2018 |
| EBB & FLO Bookshop Limited | Wholesale & retail | 2021 |
| EBM Properties Limited | Real estate | 2002 |
| Ecclescake Limited | Financial services | 2020 |
| Eccleston Cards & Gifts Ltd | Wholesale & retail | 2022 |
| Eccleston Construction Limited | Construction | 2016 |
| Eccleston Dental Practice Limited | Health & social care | 2008 |
| Eccleston DRY Cleaning Centre Limited | Other services | 2017 |
| Eccleston Electrical Services Limited | Construction | 2009 |
| Eccleston Green Filling Station Ltd | Wholesale & retail | 2009 |
| Eccleston Plastering Services Ltd | Construction | 2016 |
| Echo Quality Management Services Limited | Professional & scientific | 2021 |
| ECK Civil Engineering Ltd | Construction | 2017 |
| ECK Group Ltd | Financial services | 2026 |
| ECK Pipelines Ltd | Construction | 2023 |
| ECK Projects Ltd | Construction | 2026 |
| Eckersley Construction Consultancy Limited | Professional & scientific | 2017 |
| Eckersley Group Limited | Construction | 2014 |
| Eckersley Property Care Ltd | Construction | 2020 |
| Eclipse AH Limited | Other services | 2002 |
| Eclipse Cleaning Solutions Limited | Wholesale & retail | 2023 |
| Eclipse Locums Limited | Health & social care | 2013 |
| Eclipse Propco Limited | Real estate | 2022 |
| Eco Bright Electrical Ltd | Construction | 2021 |
| Eco Buildability Limited | Construction | 2018 |
| Eco Glamping Pods Ltd | Hospitality | 2021 |
| Eco Glazing Hub Ltd | Construction | 2024 |
| Eco Measures Marketing Ltd | Professional & scientific | 2020 |
| Eco Solutions NW Limited | Construction | 2024 |
| Eco Tidy Solutions Ltd | Water & waste | 2025 |
| Eco Volt Ltd | Construction | 2024 |
| Eco-Star Green Services Ltd | Construction | 2011 |
| Ecoferno Ltd | Professional & scientific | 2021 |
| Ecoform Ltd | Administrative & support | 2011 |
| Ecomix Holdings Limited | Manufacturing | 2025 |
| Ecommerce Development Ltd | Information & communication | 2024 |