| Unic Care Services Ltd | Health & social care | 2021 |
| Uniclad Systems Limited | Manufacturing | 1992 |
| Unicorn Pony Parties Ltd | Arts & recreation | 2022 |
| Unify Business Solutions Limited | Information & communication | 2003 |
| Unify Financial Solutions Limited | Financial services | 2006 |
| Unify Network Solutions Limited | Information & communication | 2009 |
| Unify Property Solutions Ltd | Real estate | 2006 |
| Unilateral Thinking Limited | Education | 2017 |
| Unilin Insulation UK Limited | Manufacturing | 2002 |
| Unique Forums Limited | Other services | 2014 |
| Unique Passenger Transport Ltd | Administrative & support | 2017 |
| Uniquely Crafted Contractors Ltd | Construction | 2023 |
| Uniskin Limited | Other services | 2017 |
| UNIT4 Deepdale Limited | Wholesale & retail | 2020 |
| Unitec Projects Ltd | Information & communication | 2018 |
| United Cast Bar (UK) Limited | Manufacturing | 1897 |
| United Cast Bar Limited | Professional & scientific | 2012 |
| United Commercials Limited | Administrative & support | 2000 |
| United Rental Group Limited | Administrative & support | 1990 |
| Unity Trade Ventures Ltd | Wholesale & retail | 2024 |
| Unity Underground Ltd | Wholesale & retail | 2023 |
| Universal Railroad Products Limited | Wholesale & retail | 2022 |
| Unstone Limited | Wholesale & retail | 2023 |
| Unwin Construction Limited | Construction | 2014 |
| Unwritten Occasions Limited | Administrative & support | 2024 |
| UP Strength Limited | Arts & recreation | 2019 |
| Upstainable Ltd | Manufacturing | 2020 |
| Upthebrook Limited | Financial services | 2025 |
| Upwall Films Ltd | Information & communication | 2024 |
| URA Ventures Limited | Wholesale & retail | 1997 |
| Uranie Lake Ltd | Health & social care | 2023 |
| Urban Design & Developments (Holdings) Limited | Financial services | 2011 |
| Urban Design & Developments Limited | Manufacturing | 1998 |
| Urban Facades Limited | Manufacturing | 2022 |
| Urban Landscaping Elements Limited | Professional & scientific | 2025 |
| Urban Logistics Hubs Ltd | Transport & logistics | 2018 |
| Urban Ponds Limited | Administrative & support | 2026 |
| Urban Run Limited | Arts & recreation | 2025 |
| Urban Windows, Doors & Conservatories Limited | Manufacturing | 2022 |
| Urbo Regeneration Limited | Professional & scientific | 2007 |
| Urgolfzone Ltd | Wholesale & retail | 2025 |
| Urhan Limited | Hospitality | 2018 |
| Utilities Skills People Ltd | Education | 2008 |
| Utility Planners UK Ltd | Construction | 2015 |
| Utility Stats Ltd | Professional & scientific | 2022 |
| Utility Strength Ltd | Information & communication | 2018 |
| Utni Limited | Administrative & support | 2006 |
| Utopia Holdings (Chesterfield) Limited | Financial services | 2014 |
| Utopia Tableware Limited | Wholesale & retail | 2000 |
| V & E Properties Ltd | Construction | 2018 |
| VA KEI (SVM) Limited | Hospitality | 2021 |
| Vaavoo Ltd | Information & communication | 2013 |
| Vale Career Consulting Limited | Administrative & support | 2020 |
| Vale Express Limited | Wholesale & retail | 2024 |
| Valeisa Services Limited | Health & social care | 2003 |
| Valfor Limited | Professional & scientific | 2008 |
| Validate Academy Ltd | Education | 2024 |
| Validate Consulting Limited | Professional & scientific | 2011 |
| Validate EOT Limited | Financial services | 2024 |
| Valley 68 Ltd | Hospitality | 2025 |
| Valley View (Tinkley Lane) Management Limited | Administrative & support | 2005 |
| Valleyside Landscapes Limited | Administrative & support | 2016 |
| Value My Ltd | Wholesale & retail | 2009 |
| Valued Accountancy Team Limited | Professional & scientific | 2013 |
| Valve & Process Holdings Limited | Financial services | 2024 |
| Valve & Process Solutions Limited | Wholesale & retail | 2005 |
| Valve Academy Limited | Education | 2018 |
| Valve Express Limited | Wholesale & retail | 2015 |
| Vames Access Limited | Administrative & support | 2026 |
| Van DYK Limited | Hospitality | 2019 |
| Vancannon Properties Limited | Real estate | 2026 |
| Vancannon Ventures Limited | Professional & scientific | 2025 |
| Vanguard Digital Works Ltd. | Arts & recreation | 2022 |
| Vanny's Delight Ltd | Hospitality | 2023 |
| Vantage Online Ltd | Wholesale & retail | 2017 |
| Vantree & Co Limited | Information & communication | 2025 |
| Vanz Limited | Wholesale & retail | 2024 |
| Vape HQ (Inkersall) Limited | Wholesale & retail | 2014 |
| Vape HQ Cornwall Limited | Wholesale & retail | 2016 |
| Vape HQ Truro Ltd | Wholesale & retail | 2017 |
| Vape HQ Wadebridge Ltd | Wholesale & retail | 2017 |
| Vape Hyper Store Limited | Wholesale & retail | 2023 |
| Varaidzo Violet Care Services Limited | Public administration | 2025 |
| Vargas Developments Ltd | Real estate | 2024 |
| Varley.Club Ltd. | Hospitality | 2023 |
| Varnham & Co. Limited | Professional & scientific | 2021 |
| Vaudeville Skin Piercing Limited | Other services | 2017 |
| VBH Assets Limited | Construction | 2012 |
| VCN Catering Limited | Hospitality | 2026 |
| Vecstar Limited | Manufacturing | 2004 |
| Veegem Limited | Wholesale & retail | 2018 |
| Vegagen UK Ltd | Wholesale & retail | 2021 |
| VEL Mini Market Limited | Wholesale & retail | 2018 |
| Velatus Limited | Administrative & support | 2021 |
| Velmora Virelle Limited | Health & social care | 2025 |
| Veloxion Investments Ltd | Construction | 2025 |
| Vending Machine Solutions Ltd | Wholesale & retail | 2026 |
| Vendo Matic Limited | Wholesale & retail | 2024 |
| Venuerepair... Ltd | Manufacturing | 2020 |
| Verdant Houseplants Ltd | Agriculture & fishing | 2020 |