| Ultramarine Design Ltd | Arts & recreation | 2010 |
| Umbilical Design Services Limited | Administrative & support | 2011 |
| Uneleap Ltd | Information & communication | 2018 |
| Union 3 Ltd | Hospitality | 2022 |
| Universal Profits Ltd | Wholesale & retail | 2012 |
| Unknown Clothing Company Ltd | Wholesale & retail | 2024 |
| Unruly Matters Ltd | Professional & scientific | 2022 |
| Urpeth Properties Ltd | Real estate | 2025 |
| Utility Support Solutions Limited | Construction | 2011 |
| Valued Consultancy Limited | Professional & scientific | 2012 |
| Valveland Limited | | 1981 |
| Van and Trailer Conversions Ltd | Manufacturing | 2025 |
| Vantage Projects Ltd | Professional & scientific | 2026 |
| Vaon Limited | Households | 2022 |
| Vaux Breweries Limited | Extraterritorial | 2013 |
| Velocity Marketing Ltd | Professional & scientific | 2025 |
| Veloplan Limited | Professional & scientific | 2026 |
| Vera's Birtley Ltd | Hospitality | 2025 |
| Vibz Ltd | Wholesale & retail | 2015 |
| Victoria James Trading Limited | Information & communication | 2017 |
| Viehard Ltd | Financial services | 2017 |
| Vigo Electrical Services NE Ltd | Construction | 2025 |
| Viking Plumbers Ltd | Construction | 2024 |
| Vision Resource Consulting Ltd | Professional & scientific | 2020 |
| Vmns Limited | Education | 2011 |
| Vocoda Technologies Ltd | Information & communication | 2018 |
| VT Treatment Ltd | Manufacturing | 2023 |
| Vtol Vision Ltd | Construction | 2020 |
| W Marketing Limited | Professional & scientific | 2018 |
| W.T. Fish & Chips Ltd | Hospitality | 2024 |
| Wadsworth Capital Limited | Extraterritorial | 2017 |
| WAL14 Ltd | Other services | 2019 |
| Walker Northshore Holdings Ltd | Financial services | 2026 |
| Wall Street Construction Cleaning Ltd | Administrative & support | 2021 |
| Wallgraft Limited | Real estate | 1988 |
| Wanjp Ltd | Hospitality | 2025 |
| Ward Commerce Group Limited | Wholesale & retail | 2014 |
| Warkworth Northumberland Limited | Hospitality | 2025 |
| Watch Competitions Limited | Arts & recreation | 2025 |
| Watson Investments Limited | Real estate | 2003 |
| Watsons Mini Specialist Ltd | Wholesale & retail | 2026 |
| Watson’S Heating & Plumbing Ltd | Construction | 2025 |
| WCB NE Limited | Other services | 2022 |
| WDM Civils Ltd | Construction | 2022 |
| WE Care Bespoke Ltd | Other services | 2019 |
| Wear Mini-Mix Limited | Transport & logistics | 2008 |
| Wear Valley Angling Community Interest Company | Arts & recreation | 2009 |
| Weez Limited | Financial services | 2020 |
| Wellington Properties (NE) Limited | Real estate | 2024 |
| Wellness House Chester Limited | Households | 2024 |
| Welnved Limited | Other services | 2013 |
| Wersley Consultants Ltd | Administrative & support | 2015 |
| West House Carehome Limited | Health & social care | 2000 |
| WESTGATE19 Ltd | Professional & scientific | 2019 |
| WG Entertainment Ltd | Information & communication | 2020 |
| What Villa Ltd | Manufacturing | 2026 |
| Wheatjp Ltd | Hospitality | 2025 |
| Wheelchair Vehicles North East Ltd | Wholesale & retail | 2020 |
| Whillsjp Limited | Hospitality | 2024 |
| Whitby Developers Limited | Construction | 2018 |
| White House Services Limited | Wholesale & retail | 2025 |
| Whitegates (NE) Limited | Construction | 2022 |
| Whitfield Fella Ltd | Hospitality | 2018 |
| Whitley Fabrics Limited | Wholesale & retail | 2018 |
| Wildwood Decorators Ltd | Construction | 2020 |
| William Jacobson Ltd | Mining & quarrying | 2021 |
| Willowgarth House Limited | Hospitality | 2013 |
| Willows Bakehouse Ltd | Hospitality | 2025 |
| Wilsons Travel Limited | Transport & logistics | 2025 |
| Windlestone Nursery Ltd | Wholesale & retail | 2011 |
| Windy MAC Ltd | Mining & quarrying | 2023 |
| Winken Blyth Limited | Construction | 2024 |
| Witton Park Slag Company Limited(The) | Other services | 1925 |
| Wolf Instinct Limited | Wholesale & retail | 2023 |
| Wolf Instinct Mindset Community Interest Company | Health & social care | 2023 |
| Woodlands Tree Service Limited | Administrative & support | 2025 |
| Worktalent Limited | Construction | 1996 |
| WR Group NE Ltd | Manufacturing | 2023 |
| WRG Holdings Limited | Financial services | 2024 |
| Writers of the Lost Art Ltd | Professional & scientific | 2025 |
| WRS Properties Ltd | Real estate | 2023 |
| Xiuxiu Food Ltd | Hospitality | 2023 |
| Xlsne Ltd | Administrative & support | 2023 |
| Y&I Properties Limited | Real estate | 2015 |
| Yano Barber Shop Ltd | Other services | 2022 |
| Yawaadesigns Limited | Wholesale & retail | 2025 |
| Yemanya Ltd | Other services | 2016 |
| YEW Tree Antiques Limited | Wholesale & retail | 2024 |
| Yolcote Property Management Ltd | Real estate | 2024 |
| Yorkstone Holdings Ltd | Real estate | 2021 |
| YRA Investments Ltd | Real estate | 2025 |
| YUM Yums Widdrington Limited | Real estate | 2019 |
| YUN Cuisine UK Limited | Hospitality | 2026 |
| YW Branch Limited | Real estate | 2020 |
| Z Branch Limited | Real estate | 2017 |
| Zoemick Commercials Limited | Wholesale & retail | 2005 |