| Quantify Ecology Ltd | Professional & scientific | 2026 |
| Quick Sale Gateshead Ltd | Real estate | 2022 |
| Quicksolve NE Ltd | Extraterritorial | 2024 |
| Quintessential Fashionista Ltd | Wholesale & retail | 2024 |
| Quintessential Holistic Health Ltd | Wholesale & retail | 2024 |
| Quotailor Ltd | Professional & scientific | 2026 |
| R & C Properties (North East) Limited | Extraterritorial | 2016 |
| R & J Technical Services Ltd | Professional & scientific | 2019 |
| R & K Logistics North East Limited | Transport & logistics | 2015 |
| R & R Bearings Limited | Manufacturing | 2006 |
| R P Forestry Ltd | Agriculture & fishing | 2023 |
| R&L Brunga Limited | Hospitality | 2025 |
| R&M Campers Ltd | Wholesale & retail | 2024 |
| R. Beal & Company Limited | Manufacturing | 1944 |
| R. Lewis Property Limited | Hospitality | 2007 |
| RA (North East) Limited | Administrative & support | 2018 |
| Radford Construction Services Limited | Construction | 2005 |
| Raed Inspection Services Ltd | Professional & scientific | 2016 |
| Rakshan IT Solutions Limited | Information & communication | 2022 |
| RAM Dusk Ltd | Other services | 2012 |
| Raspberry JAM Ltd | Professional & scientific | 2015 |
| RB Shops Retail Ltd | Wholesale & retail | 2023 |
| RC Forestry Ltd | Agriculture & fishing | 2026 |
| RCA Services Ltd | Manufacturing | 2017 |
| Rccp Limited | Other services | 2022 |
| Reconsify Limited | Information & communication | 2025 |
| Red Grapes Properties Ltd | Real estate | 2025 |
| Red Sky Telecom Ltd | Information & communication | 2008 |
| Red Sky Telematics Ltd | Information & communication | 2012 |
| Red Strawberry Solutions Limited | Wholesale & retail | 2011 |
| Redburn Service Station Limited | Wholesale & retail | 2026 |
| Reds PUB Limited | Hospitality | 2021 |
| Redwood Private Investments Limited | Financial services | 2020 |
| Refinemed Aesthetics Ltd | Health & social care | 2025 |
| Refresh Kitchens and Bathrooms Limited | Construction | 2022 |
| Regrowth Tree Care Ltd | Agriculture & fishing | 2025 |
| Remerge Limited | Information & communication | 2020 |
| Rep&Sweat Limited | Professional & scientific | 2018 |
| RES Couriers Limited | Transport & logistics | 2020 |
| Resicare Consultancy Ltd | Wholesale & retail | 2025 |
| Residential Property Developments Limited | Real estate | 2017 |
| Restore Laser Ltd | Administrative & support | 2026 |
| Retail Vision Ltd | Wholesale & retail | 2018 |
| Retro Renewables Ltd | Construction | 2022 |
| Retrolec Ltd | Wholesale & retail | 2017 |
| Revite Property Solutions Limited | Other services | 2016 |
| Rexan UK Ltd | Other services | 2018 |
| RG Watson Ltd | Professional & scientific | 2022 |
| RGM Maintenance Group Ltd | Manufacturing | 2020 |
| RH Auto Car & Commercials Services Ltd | Wholesale & retail | 2013 |
| Rhapsody Developments Limited | Real estate | 2003 |
| Rhfjp Ltd | Hospitality | 2025 |
| Rhue Ltd | Public administration | 2025 |
| Richard Fielding Optometry Services Limited | Other services | 2008 |
| Richard Hadyn Ellis Ltd | Professional & scientific | 2025 |
| Richard Holdsworth Engineering Ltd | Professional & scientific | 2020 |
| Richard Lamb Plastering Ltd | Construction | 2011 |
| Riding Hill Limited | Health & social care | 2010 |
| Rightclean (North East) Limited | Other services | 2012 |
| Riverside Opticians Birtley Limited | Wholesale & retail | 2025 |
| Riverside Opticians Limited | Wholesale & retail | 2020 |
| Riverside Residents Association Limited | Households | 2022 |
| RJ Groundworks (North) Ltd | Construction | 2025 |
| RJR Property Group Limited | Households | 2022 |
| RJT Engineering Solutions Ltd | Professional & scientific | 2012 |
| RK Utilities Limited | Construction | 2024 |
| RL Holbrook Limited | Professional & scientific | 2018 |
| RLC Estates Limited | Real estate | 2020 |
| RLC Tech Consulting Ltd | Information & communication | 2026 |
| RLS Homes Ltd | Real estate | 2021 |
| RMC Plumbing & Heating Services Limited | Construction | 2023 |
| RMD Homes Limited | Real estate | 2019 |
| RMM Maintenance Ltd | Construction | 2024 |
| Robert Miller & Company (Houghton) Limited | Professional & scientific | 2008 |
| Robert Miller & Company (NE) Limited | Professional & scientific | 2025 |
| Robert's Key Services Ltd | Other services | 2012 |
| Robsons Consultancy Ltd | Health & social care | 2026 |
| Rokstrat Limited | Professional & scientific | 2023 |
| Romfin Properties Ltd | Real estate | 2025 |
| Ropeservices UK Ltd | Manufacturing | 2010 |
| Rosconn Properties Limited | Real estate | 2026 |
| Rose Pelton Limited | Hospitality | 2025 |
| Roseberry Grange Community Golf Club Ltd | Arts & recreation | 2011 |
| Rosecroft Properties NE Limited | Real estate | 2021 |
| Rowlands-Parker Property Limited | Real estate | 2024 |
| Rpc-Mn Ltd | Professional & scientific | 2023 |
| RPM Vent Ltd | Construction | 2023 |
| Rrtech Limited | Wholesale & retail | 2018 |
| RSD Film Limited | Information & communication | 2019 |
| Ruben Eats Limited | Hospitality | 2023 |
| Rujan Estates Limited | Real estate | 2025 |
| Rukton Properties Limited | Real estate | 2026 |
| Russell Homes & Developments Ltd | Construction | 2022 |
| Russell Property Lettings Ltd | Real estate | 2020 |
| RW Contract Services Limited | Construction | 2018 |
| Ryder Utilities Ltd | Construction | 2024 |
| Ryedale Developments Limited | Real estate | 2017 |
| Ryze Trading Limited | Professional & scientific | 2022 |
| S & R Drinks Ltd | Wholesale & retail | 2021 |
| S B Pizza Ltd | Hospitality | 2024 |