| Digital Equity Ltd | Information & communication | 2015 |
| Digital Image Studio Ltd | Information & communication | 2003 |
| Dillon Catering Ltd | Hospitality | 2019 |
| Divinity Garden Limited | Other services | 2019 |
| Djakdaniel Limited | Administrative & support | 2018 |
| Djpf Holdings Ltd | Construction | 2026 |
| DK Building Solution Ltd | Construction | 2014 |
| DNA Motors Limited | Wholesale & retail | 2025 |
| DND Exports Ltd | Wholesale & retail | 2018 |
| Dobruna Construction Limited | Construction | 2021 |
| Doheny & Associates Limited | Information & communication | 2014 |
| Domus Fortuna Ltd | Households | 2025 |
| Dorchester Mews (New Malden) Limited | Real estate | 1981 |
| Double Espresso Shot UK Ltd | Wholesale & retail | 2024 |
| DR Amina Group Limited | Financial services | 2024 |
| DR Amina Skincare Ltd | Other services | 2021 |
| Droidity Ltd | Professional & scientific | 2019 |
| Drsjs Ltd | Health & social care | 2021 |
| DTC Global PVT Ltd | Construction | 2013 |
| Dulverton Court (Management) Limited | Administrative & support | 1977 |
| Dulverton Court Surbiton (Freehold) Limited | Administrative & support | 2002 |
| Dunlins Estates Limited | Real estate | 2017 |
| Dustbusters Cleaning (UK) Ltd | Administrative & support | 2009 |
| DUX Logistics U.K. Ltd. | Transport & logistics | 2001 |
| DVA Collision Center Ltd | Wholesale & retail | 2026 |
| Dwkw Limited | Other services | 2021 |
| E&D Quality Service Ltd | Transport & logistics | 2021 |
| E.I.M. (London) Limited | Construction | 1974 |
| E.T.S. Portsmouth Limited | Wholesale & retail | 1988 |
| Eallings Ltd | Real estate | 1997 |
| Easy Donation Manager Ltd | Information & communication | 2023 |
| Easy FIX Group Ltd | Construction | 2025 |
| Easy Gateway Solution UK Ltd | Information & communication | 2015 |
| Eaves to Leaves Property Services Ltd. | Water & waste | 2019 |
| Ebin Europe Ltd | Wholesale & retail | 2019 |
| Ecclesia Hair Ltd | Other services | 2014 |
| Eco and Hybrid Cars Limited | Wholesale & retail | 2018 |
| Eco Watt Solutions Ltd | Construction | 2023 |
| Ecohawk Limited | Professional & scientific | 2016 |
| Ecosolutions Consulting Limited | Professional & scientific | 2024 |
| Edcom Systems Ltd | Wholesale & retail | 2011 |
| Eden Cars Group Ltd | Transport & logistics | 2022 |
| Eder Construction Ltd | Construction | 2018 |
| EDI Services Ltd | Construction | 2015 |
| Eezycook UK Ltd | Information & communication | 2020 |
| Ehybrid Cars Ltd | Wholesale & retail | 2018 |
| EIS Quality Ltd | Professional & scientific | 2008 |
| EK Crescent Media Limited | Information & communication | 2021 |
| EKP Collective Limited | Administrative & support | 2024 |
| Eladda Limited | Wholesale & retail | 2022 |
| Elegua Stone Specialists Ltd | Manufacturing | 2020 |
| Eli's Kitchen Limited | Hospitality | 2024 |
| Elite Home Upgrades Limited | Construction | 2026 |
| Elite Signature Homes Limited | Construction | 2025 |
| Elitehaven Properties Ltd | Real estate | 2024 |
| Elkraft Solutions Limited | Professional & scientific | 2022 |
| ELL & SON Limited | Administrative & support | 2020 |
| Ellerton Estates Limited | Real estate | 2018 |
| Eluxury Mall & Trading Ltd | Hospitality | 2003 |
| Emanuel Piano Ltd | Education | 2004 |
| Emily Elizabeth Ltd | Arts & recreation | 2022 |
| Emin & Paul London Ltd | Wholesale & retail | 2010 |
| Emmadale Investment Company Limited | Extraterritorial | 1997 |
| Empire Automation Ltd | Information & communication | 2025 |
| Empire Interiors Ltd | Construction | 2009 |
| Emunah Europe Ltd | Wholesale & retail | 2015 |
| Enterprise Strategy Consultants Ltd | Information & communication | 2023 |
| Envora Solutions Ltd | Professional & scientific | 2025 |
| ERB Construction Ltd | Construction | 2017 |
| Erin's Estates Limited | Professional & scientific | 2017 |
| ERS Global Limited | Financial services | 2020 |
| Erudite Planning Limited | Professional & scientific | 2015 |
| ES Electrical London Ltd | Construction | 2023 |
| Escapology London Ltd | Manufacturing | 2025 |
| Essential Electrics Limited | Construction | 2016 |
| Essjay Solutions Ltd | Health & social care | 2010 |
| Esteem Services Limited | Administrative & support | 2024 |
| Esxr Ltd | Professional & scientific | 2026 |
| Eternal Watch Ltd | Wholesale & retail | 2025 |
| Eudeamon Limited | Health & social care | 2016 |
| Euro Educational Co. Limited | Education | 1994 |
| Euro Sunway Limited | Administrative & support | 2007 |
| Eurokendo Limited | Wholesale & retail | 2008 |
| Evangard Ltd | Information & communication | 2022 |
| Evergreenpetcremationservices Limited | Other services | 2023 |
| Evernutri Limited | Health & social care | 2009 |
| Evinox Energy Limited | Manufacturing | 2011 |
| Evinox Holding Ltd | Financial services | 2022 |
| Evinox Limited | Other services | 2002 |
| Evinox UK Ltd | Other services | 2002 |
| EWI Holdings Ltd | Financial services | 2024 |
| EWI Management Ltd | Financial services | 2024 |
| EWI Pro Insulation Systems Ltd | Construction | 2015 |
| EWI Store Ltd | Wholesale & retail | 2011 |
| Excellence Healthcare Services Ltd | Health & social care | 2021 |
| Exclusive Bathroom Company Ltd | Construction | 2021 |
| Executive Roomspace Limited | Real estate | 1999 |
| Executive Transit UK Limited | Real estate | 2020 |
| Expostar Europe Ltd | Other services | 2015 |
| Express Marketing SMO Limited | Administrative & support | 2025 |