| Rocce Chesham Ltd | Hospitality | 2019 |
| Rocce Woodstone Pizza Ltd | Hospitality | 2023 |
| Rockingham Mews RTM Company Limited | Households | 2010 |
| Rodi Services Limited | Manufacturing | 2005 |
| Roger Batchelor Associates Limited | Professional & scientific | 2009 |
| Roksana C.N.G. Alliyy Limited | Extraterritorial | 2025 |
| Rollins Consulting Ltd | Information & communication | 2024 |
| ROLOHANN13 Ltd. | Real estate | 2017 |
| Roofrecoating Ltd | Construction | 2022 |
| Roots Coffee Food... Limited | Hospitality | 2018 |
| Rosa Bloom Limited | Wholesale & retail | 2014 |
| Rose Spice Garden Ltd | Hospitality | 2025 |
| Rossetti House Freehold Limited | Professional & scientific | 1997 |
| Rossonic Limited | Information & communication | 2009 |
| Rovehurst Enterprises Ltd | Real estate | 2026 |
| Rovehurst Estates Limited | Real estate | 2012 |
| RPL Brickwork Construction Specialist Ltd | Construction | 2021 |
| RPL Haulage Limited | Transport & logistics | 2010 |
| RS Sharrys Ltd | Wholesale & retail | 2023 |
| RT Training Limited | Construction | 2016 |
| Rubato Global Consulting Ltd | Professional & scientific | 2013 |
| Ruby Voices Ltd | Arts & recreation | 2024 |
| Rudzki Made This Ltd | Manufacturing | 2019 |
| Russell Court (North) Management Company Limited | Real estate | 1996 |
| Russell Court (South) Management Company Limited | Other services | 1996 |
| Rutherford Homes Ltd | Extraterritorial | 2010 |
| RVA JV Limited | Construction | 2024 |
| RVA Property Services Limited | Real estate | 2016 |
| RVA UK Services Ltd | Real estate | 2015 |
| RX International Limited | Information & communication | 2023 |
| RY Infotech Ltd | Information & communication | 2023 |
| Ryans Construct Ltd | Construction | 2020 |
| Ryans Construction Development & Maintenance Limited | Construction | 2003 |
| Ryans Consulting LLP | | 2024 |
| S & F International Ltd | Wholesale & retail | 2003 |
| S & J Mortgage Services Ltd | Financial services | 2020 |
| S & N Hotels Ltd | Hospitality | 2026 |
| S & N Management Ltd | Administrative & support | 2019 |
| S Creative Ltd | Information & communication | 2013 |
| S D Property Investment Group Limited | Real estate | 2019 |
| S Eames Horticulture Ltd | Administrative & support | 2026 |
| S J M and Co Limited | Construction | 2014 |
| S S Refurb Limited | Wholesale & retail | 2024 |
| S&S Consulting London Limited | Professional & scientific | 2015 |
| S. T. Auto Services Limited | Wholesale & retail | 2009 |
| S.H.J. Hospital Pipelines Limited | Health & social care | 1973 |
| S.J Maye Construction Limited | Construction | 2023 |
| S.J.Jarrett Ltd | Administrative & support | 2013 |
| S.O.D.S.P.S.G Ltd. | Extraterritorial | 2025 |
| S.R.S. Microsystems Limited | Wholesale & retail | 1981 |
| S.Taylor Electrical Limited | Construction | 2022 |
| S.W.C Window Cleaners Ltd | Other services | 2017 |
| S11 Investments Limited | Other services | 2011 |
| Saab Consulting Limited | Information & communication | 2024 |
| Sabau Spedition Ltd | Transport & logistics | 2019 |
| Sadie Tilbury Limited | Manufacturing | 2013 |
| Sadler & Daughters Ltd | Hospitality | 2026 |
| Safa Investment Ltd | Real estate | 2013 |
| Safer Start Work Solutions Ltd | Professional & scientific | 2024 |
| Safety First Fire Security Ltd | Administrative & support | 2019 |
| SAFETY4YOU Ltd | Professional & scientific | 2011 |
| Safr Medical Ltd | Health & social care | 2025 |
| Salah Flow Ltd | Information & communication | 2026 |
| Sales Geek Central & South Bucks Ltd | Professional & scientific | 2024 |
| Saluja Technologies Limited | Information & communication | 2012 |
| Salujaboysellem Limited | Wholesale & retail | 2021 |
| Samar Home Rentals Ltd | Real estate | 2023 |
| SAN Clemente Limited | Information & communication | 2023 |
| Santerel Limited | Administrative & support | 2021 |
| SAP Accountancy Limited | Professional & scientific | 2008 |
| Sarah Hibbert Limited | Professional & scientific | 2003 |
| SAS Construction & Roofing Specialists Limited | Construction | 2019 |
| Sasi Products and Services Limited | Construction | 2022 |
| Sasolo Ltd | Information & communication | 2010 |
| SAT Management Ltd | Real estate | 2025 |
| Savafrei Ltd | Wholesale & retail | 2019 |
| SB Signs Ltd | Wholesale & retail | 2021 |
| SBG International Ltd | Arts & recreation | 2019 |
| Scenic Hall Ltd | Information & communication | 2013 |
| Schimmelpfennig Motion Ltd | Professional & scientific | 2012 |
| Schnoodles Ltd | Other services | 2014 |
| Scholars Tutorial Ltd | Education | 2025 |
| School Business Manager (UK) Limited | Wholesale & retail | 2023 |
| Scientechnix Limited | Extraterritorial | 2016 |
| Scorpos Construction Ltd | Extraterritorial | 2009 |
| Scorpos Group Ltd | Administrative & support | 2009 |
| Scorpos Limited | Administrative & support | 2000 |
| Scotts Building and Design Ltd | Construction | 2021 |
| Screenspace Live Limited | Administrative & support | 2023 |
| Scribe-Mate Limited | Wholesale & retail | 2024 |
| Scrubd International Trading Group Ltd | Wholesale & retail | 2026 |
| Scruffy to Fluffy Dogs Ltd | Other services | 2020 |
| Scrupulous Ltd | Wholesale & retail | 2025 |
| Scsp Electrics Limited | Construction | 2017 |
| Sculpins Ltd | Professional & scientific | 2023 |
| SD Plant Ltd | Administrative & support | 2019 |
| SDB Express Ltd | Other services | 2017 |
| Seabrook Architects Partnership Ltd | Professional & scientific | 2016 |
| Seabrook Investments Ltd | Real estate | 2019 |
| Seabrook Investments One Ltd | Real estate | 2020 |