| Craftisanlabs Limited | Information & communication | 2025 |
| Cranatt Construction Ltd. | Construction | 1997 |
| Cranatt Limited | Financial services | 2022 |
| Cranham Common Trust | Other services | 2008 |
| Craniomandibularclinics Limited | Health & social care | 2012 |
| Cranley Management Company (1991) Limited | Households | 1991 |
| Crashtek Limited | Information & communication | 2007 |
| Cravio Ltd | Hospitality | 2026 |
| CRC Newlands Limited | Hospitality | 2015 |
| CRC Site Investigation Ltd | Professional & scientific | 2022 |
| CRE8-IVE Homes Limited | Real estate | 2014 |
| Cream Hairdressing Ltd | Other services | 2003 |
| Creampot Furnishings Ltd | Other services | 2025 |
| Crease Releaser Limited | Hospitality | 2025 |
| Create and Bloom Crafts Limited | Wholesale & retail | 2024 |
| Create Gloucestershire Limited | Arts & recreation | 2011 |
| Create on the Square Community Interest Company | Administrative & support | 2015 |
| Creative Care (Leicester) Limited | Health & social care | 2016 |
| Creative Carpentry Kitchens & Bathrooms Ltd | Manufacturing | 2021 |
| Creative Garden Studios Limited | Administrative & support | 2018 |
| Creative Mischief Ltd | Professional & scientific | 2025 |
| Creative Publishing Solutions Limited | Wholesale & retail | 1990 |
| Creative Web Expert Limited | Information & communication | 2025 |
| Creditor Hub Limited | Extraterritorial | 2011 |
| Cree Restaurants Ltd | Hospitality | 2024 |
| Cremyll Consultancy Limited | Information & communication | 2013 |
| Cremyllsbury Limited | Construction | 2018 |
| Creotec Limited | Information & communication | 2000 |
| Crescent Place Ltd | Construction | 2023 |
| Crestview Advisory UK Ltd | Financial services | 2025 |
| Crezium Ltd | Wholesale & retail | 2025 |
| Crickett Estates Limited | Real estate | 2024 |
| Crickett Studios Limited | Real estate | 2025 |
| Crickley Associates LLP | | 2012 |
| Crimson Wire Limited | Information & communication | 2012 |
| Crisisvr Ltd | Professional & scientific | 2021 |
| Crissy Ltd | Wholesale & retail | 2013 |
| Cristie (UK) Limited | Real estate | 1936 |
| Critical Flow Holdings Limited | Financial services | 2022 |
| Critical Flow Investments Limited | Real estate | 2022 |
| Critical Flow Systems Limited | Professional & scientific | 1996 |
| CRM114 Limited | Transport & logistics | 2026 |
| Crocker Estates Limited | Professional & scientific | 2007 |
| Crocker House Limited | Hospitality | 2003 |
| Croft & Jones Limited | Hospitality | 2015 |
| Croft Farm Enterprises Limited | Financial services | 2024 |
| Croft Gardens (Gretton) Management Company Limited | Households | 2025 |
| Croft Law Ltd | Professional & scientific | 2015 |
| Croft Solicitors Ltd. | Professional & scientific | 2010 |
| Cromer Holdings Limited | Real estate | 2024 |
| Cromwell Court Battledown Management Limited | Real estate | 2021 |
| Crona's Candles Limited | Wholesale & retail | 2022 |
| Cronk Enterprise Group Ltd | Financial services | 2026 |
| Crooks Industrial Estate Limited | Real estate | 1941 |
| Croome Property Ltd | Real estate | 2018 |
| Crop Beer Ltd | Manufacturing | 2021 |
| Cropcare Contractors Ltd | Wholesale & retail | 2013 |
| Cross & Co (Builders) Ltd | Construction | 2012 |
| Cross Communication and Bluetooth Marketing Limited | Professional & scientific | 2017 |
| Crossbow Partners Ltd | Real estate | 2017 |
| Crossfire Holdings Ltd | Professional & scientific | 2023 |
| Crossfit (Cheltenham) Ltd | Arts & recreation | 2012 |
| Crossfit Cheltenham Community CIC | Education | 2026 |
| Crossley and Co Accountants LLP | | 2026 |
| Crossways (Stow on the Wold) Management Company Limited | Households | 2016 |
| Crowdhandler Ltd | Information & communication | 2020 |
| Crowe Productions Limited | Information & communication | 2007 |
| Crowley Controls Ltd | Information & communication | 2018 |
| Crown DRY Cleaners (Cheltenham) Limited | Other services | 2001 |
| Crown Education Ltd | Education | 2020 |
| Crown House Restaurant Ltd | Hospitality | 2025 |
| Crown Jewels Racing Limited | Information & communication | 2023 |
| Crowther Group Limited | Real estate | 2021 |
| Crowther Holdings Limited | Financial services | 2006 |
| Crowther Property Holdings Limited | Financial services | 2022 |
| CRS Fine Wine Brokers Ltd | Wholesale & retail | 2014 |
| Crucible Ventures Limited | Financial services | 2016 |
| Cruise Connections Limited | Administrative & support | 2011 |
| Cruise Offers Limited | Extraterritorial | 2011 |
| Crunchy Tomatoes Limited | Information & communication | 2019 |
| Crusty Investment Company Limited | Administrative & support | 2007 |
| Cruxpoint Partners Limited | Professional & scientific | 2025 |
| Crypto RIG Hosting Limited | Information & communication | 2021 |
| Crystal Cruises Finance Ltd | Financial services | 2024 |
| Crystal Cruises UK Ltd | Administrative & support | 2022 |
| Crystal Design Services Limited | Information & communication | 1994 |
| Crystal Frog Ltd | Information & communication | 2016 |
| Crystal Image (UK) Limited | Arts & recreation | 1992 |
| Crystal KIN Limited | Health & social care | 2023 |
| CS Calzature Limited | Wholesale & retail | 2021 |
| CS Clothing Ltd | Wholesale & retail | 2024 |
| CS Cotswold Properties Ltd | Administrative & support | 2018 |
| CS4 Trading Limited | Wholesale & retail | 2024 |
| Csaace LLP | | 2025 |
| Csag Merchants Limited | Construction | 2015 |
| Cspc (Pharmacy) Limited | Extraterritorial | 2007 |
| CTA Tax and Business Services Ltd | Financial services | 2023 |
| CTD Racing Ltd | Arts & recreation | 2022 |
| CTI Communications Limited | Information & communication | 2005 |
| Ctrlaltrecycling Ltd | Information & communication | 2026 |