| Mediprax Limited | Health & social care | 2025 |
| Mediscan Ltd | Extraterritorial | 2022 |
| Mediterm Training Ltd | Professional & scientific | 2008 |
| Medsar Ltd | Wholesale & retail | 2022 |
| Medusa Hair Salon Ltd | Other services | 2021 |
| Medwise Consultancy Ltd | Health & social care | 2014 |
| Meechai Thai Cafe Limited | Hospitality | 2025 |
| Meechu Trading Limited | Wholesale & retail | 2020 |
| Meer Aslam Ltd | Wholesale & retail | 2024 |
| MEG Wire Ltd | Wholesale & retail | 2003 |
| Megasun (Eccles) Limited | Other services | 2012 |
| Mehaks Glamour Lounge Ltd | Other services | 2019 |
| Mell's Kitchen Ltd | Manufacturing | 2024 |
| Mellor Place MC Ltd | Administrative & support | 2021 |
| Mellor Road Garage Limited | Wholesale & retail | 2018 |
| Melrose Court Management (Wilmslow) Limited | Households | 1985 |
| Melroy Properties Ltd | Real estate | 2025 |
| Memh Ltd | Hospitality | 2026 |
| Menchi Properties Ltd | Real estate | 2024 |
| Mensah Entertainment Limited | Professional & scientific | 2017 |
| Merchant Online Limited | Wholesale & retail | 2022 |
| Mere View (Astbury) Ltd | Construction | 2018 |
| Mere View Management Company Limited | Households | 2019 |
| Meriton Projects Ltd | Construction | 2026 |
| Metallicum Corp Limited | Wholesale & retail | 2025 |
| Metani DRY Wall Finishings Ltd | Construction | 2023 |
| Metazon Limited | Wholesale & retail | 2021 |
| Metbuild Framing Solutions Limited | Construction | 2021 |
| Meteor Human Capital Limited | Information & communication | 2023 |
| Metric Manchester Ltd | Extraterritorial | 2021 |
| Metsi Ltd | Wholesale & retail | 2022 |
| Metstract Ltd | Manufacturing | 2025 |
| Mett 8 Ltd | Professional & scientific | 2022 |
| Meze Dine Limited | Hospitality | 2024 |
| MFG Investments Ltd | Construction | 2012 |
| MFM Property Holdings Ltd | Real estate | 2026 |
| MG Construction Design and Build Ltd | Construction | 2020 |
| MH & NP Consultants Ltd | Professional & scientific | 2016 |
| MH Trading Services Ltd | Wholesale & retail | 2024 |
| MH Transport 2000 Ltd | Transport & logistics | 2021 |
| MHK Commercial Limited | Wholesale & retail | 2026 |
| MIA Mendes Ltd | Professional & scientific | 2026 |
| MIA Slater Social Ltd | Information & communication | 2025 |
| Miabelle Photography Ltd | Professional & scientific | 2018 |
| Mialex Limited | Professional & scientific | 2017 |
| Michaelodonnell Limited | Professional & scientific | 2026 |
| Michelle Mcdermott Productions Limited | Information & communication | 2015 |
| Micho Design Ltd | Hospitality | 2018 |
| Microtech Repairs Ltd | Other services | 2021 |
| Middle Earth Properties 2 Limited | Real estate | 2026 |
| Middle Earth Properties Limited | Real estate | 2012 |
| Midway Car Sales Limited | Wholesale & retail | 2013 |
| Migitec Ltd | Wholesale & retail | 2023 |
| Mikado Coral (Manchester) Limited | Construction | 1978 |
| Mikado Coral International Limited | Professional & scientific | 1979 |
| Mikaeel Group Ltd | Administrative & support | 2024 |
| Mike Wakefield Architectures Ltd | Information & communication | 2016 |
| Mike Wakefield IT Consultancy Ltd | Information & communication | 2023 |
| Mikhailtex Ltd | Wholesale & retail | 2025 |
| Milcrest Construction Limited | Construction | 1998 |
| Millan & Jimenez Barberia Limited | Other services | 2024 |
| Miller Business Training Associates Ltd | Professional & scientific | 2011 |
| Millkmedia Ltd | Information & communication | 2020 |
| Millstream Saddlery Limited | Wholesale & retail | 2021 |
| Millwood Health & Beauty Ltd | Professional & scientific | 2019 |
| Milton Crescent (Cheadle) Management Company Limited | Real estate | 2007 |
| MIM Joinery Limited | Construction | 2023 |
| Mimic Engineering Limited | Professional & scientific | 2008 |
| Minahan Hirst & Co Limited | Professional & scientific | 2009 |
| Minara Foods Limited | Manufacturing | 1999 |
| Mindconnect Ltd | Health & social care | 2026 |
| Minds Behind Limited | Information & communication | 2021 |
| Minds Support Ltd | Health & social care | 2024 |
| Minhas Carriage UK Ltd | Transport & logistics | 2024 |
| Mini Miners Nursery Ltd | Health & social care | 2017 |
| Mini Montesaurs Limited | Health & social care | 2022 |
| Minimal Escapes Limited | Real estate | 2021 |
| Minimal Homes Limited | Real estate | 2023 |
| Ministry of Humanity Limited | Information & communication | 2022 |
| Minos Property Limited | Real estate | 2025 |
| Minuzac Ltd | Professional & scientific | 2016 |
| Minx Clothing (International) Ltd | Wholesale & retail | 2023 |
| MIR Properties NW Limited | Real estate | 2026 |
| Mirac Group Limited | Wholesale & retail | 2023 |
| Miran Consulting Limited | Professional & scientific | 2007 |
| Miri Roshni Initiatives Limited | Construction | 2023 |
| Mirpropertiesnwltd Ltd | Real estate | 2026 |
| Mirrorport Limited | Information & communication | 2013 |
| Mirtorabi Investments Ltd | Financial services | 2023 |
| Misba Ltd | Wholesale & retail | 2021 |
| Misia Rosa Ltd | Wholesale & retail | 2026 |
| MISITO2010 Ltd | Wholesale & retail | 2011 |
| Miss Barbette Ltd | Other services | 2018 |
| Mississippi Plumbing and Emergency Limited | Construction | 2023 |
| Mistral Court (Management) Limited | Households | 1976 |
| Mistry Swire Architects Ltd | Professional & scientific | 2021 |
| Mitchell Williams & Company Limited | Real estate | 2015 |
| Mitigo Limited | Information & communication | 2024 |
| MJ and AJ Dingle Holdings Limited | Financial services | 2025 |
| MJB Legal Costs Ltd | Professional & scientific | 2025 |