| M20 Solutions Ltd | Information & communication | 2017 |
| M3 Plumbing & Heating Installation Ltd | Construction | 2024 |
| MA Consultants Ltd | Information & communication | 2011 |
| MA Food Store Ltd | Wholesale & retail | 2019 |
| MAA G Limited | Wholesale & retail | 2019 |
| Maano Ltd | Hospitality | 2026 |
| Mabs Surgical Limited | Health & social care | 2024 |
| MAC Holdings 1 Ltd | Financial services | 2025 |
| Mac&Anna Ltd | Transport & logistics | 2021 |
| Macoo Medicals Limited | Health & social care | 2016 |
| MAD Consultancy Ltd | Information & communication | 2018 |
| MAD Supplements Ltd | Wholesale & retail | 2025 |
| Madison Medical Professionals Ltd | Administrative & support | 2009 |
| Mafuta & Kanege Properties Ltd | Real estate | 2026 |
| Magic Carpets Co. Limited | Wholesale & retail | 1967 |
| Magna Apex Holdings Ltd | Real estate | 2024 |
| Magnate Clothing Ltd | Wholesale & retail | 2022 |
| Magnetics One Ltd | Wholesale & retail | 2014 |
| Magnum Opus Property Services Ltd | Construction | 2019 |
| Magnum Opus Repairs Ltd | Manufacturing | 2014 |
| Magnus Insurance Services Limited | Financial services | 2007 |
| Mahmood M Medical Services Ltd | Health & social care | 2021 |
| Mahtah Ltd | Wholesale & retail | 2024 |
| Maid of Honour Limited | Administrative & support | 2022 |
| Main & Main Estate Agents Limited | Real estate | 2005 |
| Main and Main Commercial Limited | Real estate | 2025 |
| Maincor Limited | Extraterritorial | 2007 |
| Maine Stand Investments Limited | Financial services | 2024 |
| Maison Haus Limited | Real estate | 2017 |
| Maison Haus Management Limited | Real estate | 2017 |
| Maivero Limited | Information & communication | 2025 |
| Majestic Oak Limited | Professional & scientific | 2005 |
| MAK Retail Limited | Wholesale & retail | 2015 |
| Make YOU UP Limited | Health & social care | 2015 |
| Malab Ltd | Wholesale & retail | 2022 |
| Maleesa Services Limited | Health & social care | 2015 |
| Malik Consultancy Limited | Professional & scientific | 2017 |
| Malik Property Solutions Limited | Real estate | 2024 |
| Maliksharif Ltd | Health & social care | 2023 |
| Malkan Properties 2 Go Limited | Real estate | 2022 |
| Malkan Properties Ltd | Real estate | 2022 |
| Malona Developments Limited | Real estate | 2024 |
| Maman Mobile Chef Ltd | Hospitality | 2021 |
| Mamu Consulting Ltd | Professional & scientific | 2026 |
| MAN Hair Studio Ltd | Other services | 2020 |
| Manahil Farooq Ltd | Wholesale & retail | 2025 |
| Mancbeeconsulting Ltd | Information & communication | 2022 |
| Manchester Aesthetics Limited | Manufacturing | 2019 |
| Manchester Bhse Limited | Construction | 2022 |
| Manchester Burgers Ltd | Wholesale & retail | 2024 |
| Manchester Dream Property Ltd | Construction | 2023 |
| Manchester Electronic Music CIC | Arts & recreation | 2023 |
| Manchester Energy Partnership Limited | Construction | 2016 |
| Manchester EPC Ltd | Other services | 2020 |
| Manchester Feet Podiatry Limited | Health & social care | 2021 |
| Manchester Fertility Nominee Limited | Real estate | 2012 |
| Manchester Fertility Property Limited | Real estate | 2012 |
| Manchester Fertility Services Limited. | Health & social care | 1985 |
| Manchester Flat Roofing Ltd | Construction | 2025 |
| Manchester Fruit & VEG Ltd | Wholesale & retail | 2018 |
| Manchester Hospitality Ltd | Hospitality | 2026 |
| Manchester International Academy Ltd | Education | 2013 |
| Manchester Laser Clinic Limited | Other services | 2020 |
| Manchester Lettings Limited | Real estate | 2010 |
| Manchester Libraries Trust | Arts & recreation | 2012 |
| Manchester Line Ltd | Transport & logistics | 2025 |
| Manchester Mortgage Solutions Limited | Financial services | 2022 |
| Manchester MSK Radiology Ltd | Health & social care | 2020 |
| Manchester Outdoor Fitness TAZ Ltd | Arts & recreation | 2019 |
| Manchester Pearl Ltd | Construction | 2016 |
| Manchester Pharma Ltd | Manufacturing | 2017 |
| Manchester Property Refurbs Limited | Construction | 2013 |
| Manchester Prostate Clinic Ltd | Health & social care | 2025 |
| Manchester Refrigerants Ltd | Wholesale & retail | 2018 |
| Manchester Renewables Group Limited | Construction | 2025 |
| Manchester Renewables Limited | Construction | 2022 |
| Manchester Roses Homecare Ltd | Health & social care | 2022 |
| Manchester Shredding Limited | Water & waste | 2011 |
| Manchester Technical Services Limited | Professional & scientific | 2013 |
| Manchester Urology LLP | | 2009 |
| Manchester Waste Management Ltd | Water & waste | 2025 |
| Mancini UK Limited | Real estate | 2002 |
| Mancunian Dentalcare Limited | Health & social care | 2021 |
| Mani Travel Ltd | Transport & logistics | 2023 |
| Manimu Limited | Wholesale & retail | 2025 |
| Manor Financial Advice Ltd | Financial services | 2011 |
| Manor Place Management Albert Road Limited | Real estate | 2017 |
| Mansion Property Management Limited | Real estate | 2008 |
| MAP Investments NW Limited | Real estate | 2024 |
| Maple Properties (Cheadle Hulme) Limited | Real estate | 1958 |
| Mappyad Ltd | Professional & scientific | 2008 |
| Maradona Developments Ltd | Construction | 2025 |
| Maral Interiors UK Ltd | Wholesale & retail | 2022 |
| MARC1HEATING Ltd | Construction | 2008 |
| Mardle Consulting Limited | Professional & scientific | 2025 |
| Maria Rasul Ltd | Public administration | 2020 |
| Marine Bathrooms Limited | Construction | 2021 |
| Marine House Developments Limited | Construction | 2025 |
| Mark Davenport Builders Limited | Administrative & support | 2018 |
| Mark Francis Properties Ltd | Real estate | 2020 |