| R1SE Fit Limited | Arts & recreation | 2023 |
| Rafa Consulting Ltd | Professional & scientific | 2015 |
| Railway Engineering Management Limited | Professional & scientific | 2006 |
| Rapida Solutions Ltd | Professional & scientific | 2012 |
| RAW Material Supplies Ltd | Wholesale & retail | 2020 |
| Reddington Technical Services Ltd | Professional & scientific | 2007 |
| Rejuvenate Hair Medical Ltd | Other services | 2025 |
| Retirement Solutions (UK) Limited | Financial services | 2007 |
| Retirement Solutions Equity Release Limited | Financial services | 2022 |
| Reventon Ltd | Professional & scientific | 2006 |
| REW Management Limited | Professional & scientific | 2026 |
| RHA Educational Consultancy Limited | Education | 2007 |
| Richard Shadbolt Video Editing Ltd | Information & communication | 2012 |
| Richardbrooks.Org Limited | Professional & scientific | 2017 |
| Risst Ltd | Health & social care | 2023 |
| Rita's Homemade Holidays Ltd | Administrative & support | 2016 |
| RMB Investment and Development Limited | Real estate | 2023 |
| RNH Management Services Ltd | Construction | 2022 |
| Roberts Mcbain Mortgage & Finance Ltd | Financial services | 2016 |
| Rosh FD Limited | Professional & scientific | 2006 |
| Rosley Data Services Ltd | Information & communication | 2023 |
| Rowe Development Services Limited | Administrative & support | 2004 |
| Roylin Properties Ltd | Real estate | 2019 |
| Ruben Property Management Ltd | Real estate | 2017 |
| Rumours Hair Ltd | Other services | 2003 |
| RW Bennison & Sons Ltd | Construction | 2024 |
| S Hunt Engineering Ltd | Professional & scientific | 2024 |
| Salisbury Real Estate Ltd | Professional & scientific | 2012 |
| Samchi Ltd | Administrative & support | 2017 |
| Sandbanner Ltd | Administrative & support | 2004 |
| Sandmount Estates Ltd | Real estate | 2006 |
| Scans for Fans Ltd | Manufacturing | 2023 |
| Schilthorn Strategies Limited | Information & communication | 2018 |
| Sdrl Properties UK Limited | Real estate | 2019 |
| Seasons Art Macclesfield Ltd | Arts & recreation | 2025 |
| Sebright Financial Services Limited | Financial services | 2021 |
| Selini Limited | Professional & scientific | 2003 |
| Service Telecom Ltd | Information & communication | 2003 |
| Setantii Property Ltd | Financial services | 2014 |
| Setcontrol Limited | Administrative & support | 1991 |
| Seven Mile Consulting Limited | Professional & scientific | 2024 |
| Shadow Worldwide Limited | Other services | 2025 |
| Shah Holdco Limited | Administrative & support | 2025 |
| Shaw Design Limited | Professional & scientific | 2000 |
| Shelikes Manchester Limited | Wholesale & retail | 2015 |
| Shoesandpivots Ltd | Other services | 2020 |
| Shore Control Ltd | Professional & scientific | 2007 |
| Short Construction Holdco Limited | Construction | 2026 |
| Sian Taylor Coaching Ltd | Professional & scientific | 2017 |
| Simply ICT Solutions Limited | Information & communication | 2011 |
| Sipnal Limited | Professional & scientific | 2011 |
| Sjdm Engineering Ltd | Professional & scientific | 2024 |
| SK Lifestyle Ltd | Wholesale & retail | 2010 |
| Skybeam Ltd | Administrative & support | 2004 |
| Sleepybear Limited | Information & communication | 2009 |
| SLI Chemicals Holdings Ltd | Wholesale & retail | 1999 |
| SM Cheshire Property Improvements Ltd | Construction | 2017 |
| Smart Industrial Services Ltd | Professional & scientific | 2023 |
| SNG Security Ltd | Information & communication | 2017 |
| Snowtech Limited | Professional & scientific | 1999 |
| Soloista Limited | Information & communication | 2013 |
| Soloista Properties Ltd | Real estate | 2017 |
| SOLUTIONS4MANAGEMENT Ltd | Professional & scientific | 2023 |
| Soulken Ltd | Professional & scientific | 2025 |
| South MCR Autos Ltd | Wholesale & retail | 2015 |
| Spargrange Contracts Limited | Professional & scientific | 1986 |
| Spectrum Power Limited | Construction | 2015 |
| Spinone 2020 Ltd | Professional & scientific | 2019 |
| SQ Commercial Services Ltd | Professional & scientific | 2012 |
| SQN Global Limited | Professional & scientific | 2011 |
| SSI Engineering Limited | Professional & scientific | 1998 |
| Stepside Engineering Ltd | Administrative & support | 2002 |
| Steve Bruce Limited | Real estate | 1992 |
| Stuart Smith Engineering & Design Limited | Professional & scientific | 2024 |
| Supercar Sisters Ltd | Wholesale & retail | 2022 |
| SVO Editing Ltd | Information & communication | 2022 |
| System Engineering Ltd | Professional & scientific | 1997 |
| SZK Consulting Ltd | Professional & scientific | 2021 |
| T Bentley Mechanical Services Ltd | Professional & scientific | 2006 |
| Task Design Limited | Professional & scientific | 2008 |
| Tattoo Productions Limited | Water & waste | 1983 |
| Taylor Process Ltd | Professional & scientific | 2008 |
| TCP Engineering Ltd | Professional & scientific | 2014 |
| Technology Solutions Distribution Ltd | Wholesale & retail | 2022 |
| Techrisk Limited | Administrative & support | 2004 |
| Testing and Commissioning Services Ltd | Professional & scientific | 2006 |
| Teylu Properties Ltd | Real estate | 2021 |
| That Property Limited | Real estate | 2011 |
| THE Brickworks (Bury) Limited | Construction | 2013 |
| THE BWA Consultancy Ltd | Other services | 2006 |
| THE Chamber Tattoo Studio Limited | Other services | 2025 |
| THE Change Room Ltd | Health & social care | 2013 |
| THE Glasses Warehouse Ltd | Manufacturing | 2011 |
| THE Home Supermarket Ltd | Real estate | 2008 |
| THE Inkstitute Ltd | Arts & recreation | 2010 |
| THE Liverpool Legal Recruitment Company Limited | Administrative & support | 2006 |
| THE Morris Minor Millennium Company Limited | Wholesale & retail | 1978 |
| THE Personal Security App Limited | Information & communication | 2020 |
| THE Salt Lake Consultancy Limited | Professional & scientific | 1998 |
| Thethinkingmind Coaching Ltd | Professional & scientific | 2016 |