| S & R Garden Maintenance Limited | Administrative & support | 2009 |
| S & S Painting and Decorating Contractors Ltd | Construction | 2004 |
| S & T Painting and Decorating Ltd | Construction | 2023 |
| S Browns Decorators Limited | Construction | 2021 |
| S C Construction Ltd | Construction | 2017 |
| S D Property Management Limited | Other services | 2013 |
| S Hunjan Ltd | Wholesale & retail | 2015 |
| S Jefferies Limited | Health & social care | 2015 |
| S M Carpets and Flooring Ltd | Construction | 2018 |
| S MAX Transport Ltd | Transport & logistics | 2026 |
| S P Mills Ltd | Construction | 2016 |
| S P W Electrical Limited | Construction | 1994 |
| S Prasad Cardiology Limited | Health & social care | 2024 |
| S T Shoes Ltd | Wholesale & retail | 2013 |
| S&A Supports Ltd | Wholesale & retail | 2021 |
| S&G Cons Ltd | Construction | 2021 |
| S&K Kent Enterprises Limited | Wholesale & retail | 2017 |
| S&K Kent Property Ltd | Real estate | 2025 |
| S&K Properties Group Ltd | Real estate | 2023 |
| S&Lw Ltd | Construction | 2021 |
| S&M Convenience Store Ltd | Wholesale & retail | 2022 |
| S&R Logistics Ltd | Transport & logistics | 2019 |
| S&T Bathroom Build Company Limited | Construction | 2019 |
| S. Miles Plumbing & Heating Limited | Other services | 2014 |
| S.B.M. Property Management Limited | Households | 1989 |
| S.C.A. - Shipping Consultants Associated Ltd. | Hospitality | 2000 |
| S.E.M.E.C (Electrical) Limited | Administrative & support | 2012 |
| S.K Planning Consult Limited | Professional & scientific | 2025 |
| S.S.S Scaffolding Ltd | Construction | 2018 |
| S.T. Construction (London) Ltd | Construction | 2011 |
| S3V2R1 Limited | Wholesale & retail | 2019 |
| S8LOGISTICS Ltd | Construction | 2019 |
| SA Neal Ltd | Construction | 2012 |
| SA Utilities Consultant Ltd | Professional & scientific | 2021 |
| SA3 Brothers Ltd | Real estate | 2026 |
| Saailes Limited | Information & communication | 2025 |
| SAB Property Solutions Ltd | Real estate | 2023 |
| Sabre Commercial Holdings Ltd | Construction | 2022 |
| Sabre Security & R.F. Systems Limited | Administrative & support | 1992 |
| Sabre Security Maintenance Limited | Extraterritorial | 2003 |
| Sabsar Ltd | Information & communication | 2019 |
| Sacred Renewal Ltd | Other services | 2026 |
| Sadi Enterprise Ltd | Health & social care | 2022 |
| Sadi Homes Ltd | Real estate | 2023 |
| Safa & Marwa Ltd | Hospitality | 2025 |
| Safa Grocery Store Ltd | Wholesale & retail | 2026 |
| Safa Hair & Cosmetics Ltd | Wholesale & retail | 2023 |
| Safe Arms | Education | 2016 |
| Safe Aura Limited | Other services | 2023 |
| Safe Elimination Services Ltd | Water & waste | 2018 |
| Safe Place Properties Ltd | Real estate | 2025 |
| Safe-Ashored Ltd | Professional & scientific | 2025 |
| Safeguard Corporate Health & Safety Ltd | Professional & scientific | 2018 |
| Safeguard Electrical Services Ltd | Construction | 2023 |
| Safety & Management Solutions Limited | Professional & scientific | 2004 |
| Safety Critical Systems Ltd | Professional & scientific | 2025 |
| Sagah Properties Ltd | Real estate | 2023 |
| Sahara Group Holdings Ltd | Financial services | 2023 |
| Sahara Suites Accommodation Limited | Real estate | 2025 |
| Sahely Limited | Health & social care | 2012 |
| Sajneg Ltd | Wholesale & retail | 2025 |
| Sakti Logistics Ltd | Transport & logistics | 2022 |
| Sald Ukay Ltd | Information & communication | 2002 |
| Salem Springs Limited | Real estate | 2026 |
| Sales Chief Ltd | Education | 2024 |
| Salimi Ltd | Health & social care | 2015 |
| Sally Hallam Health & Wellbeing Ltd | Health & social care | 2019 |
| Salma's Care Services Ltd | Health & social care | 2022 |
| Salmon Estates Kent Limited | Real estate | 2024 |
| Salon Couture Limited | Administrative & support | 2017 |
| Salone Network Ltd | Information & communication | 2024 |
| Salonserve Limited | Real estate | 2006 |
| Salt Bar Ltd | Hospitality | 2024 |
| Salt Bespoke Limited | Extraterritorial | 2026 |
| Saltin Properties Ltd | Real estate | 2023 |
| SAM Goad Distribution Ltd | Wholesale & retail | 2023 |
| SAM Unbeatable Limited | Professional & scientific | 2023 |
| Sam's Total Protection Ltd | Construction | 2026 |
| Sambhana Care Limited | Public administration | 2018 |
| Sameri Limited | Administrative & support | 2013 |
| Samestem Limited | Real estate | 2024 |
| Samford Property Development Ltd | Professional & scientific | 2024 |
| Sammy Cornerstone Ltd | Real estate | 2026 |
| Sammy’S Sunflowers Ltd | Wholesale & retail | 2025 |
| Sandbanks Coastal Equipment Limited | Administrative & support | 2023 |
| Sandbox Garden Café Limited | Hospitality | 2022 |
| Sandwich Leisure Limited | Hospitality | 2006 |
| Sandwich Leisure Residential Limited | Hospitality | 2012 |
| Sandy Adventures Ltd | Arts & recreation | 2026 |
| Sanimara Ltd | Information & communication | 2026 |
| Santander Logistics Limited | Wholesale & retail | 2016 |
| Saoirse Brown Coaching Ltd | Other services | 2026 |
| Sapphire Design and Construction (South East) Limited | Construction | 2016 |
| Sapphire Software Services Limited | Information & communication | 2025 |
| Sapsystems Limited | Professional & scientific | 2017 |
| Sarah Faktor Holistic Therapies Limited | Other services | 2023 |
| Sarah Omope Ltd | Manufacturing | 2025 |
| Sarah Semakula Private Services Ltd | Health & social care | 2022 |
| Sarahannah Limited | Health & social care | 2010 |
| Sarts Ltd | Construction | 2018 |