| Deepsight Analytics Ltd | Professional & scientific | 2025 |
| Deerswood Close Management (Caterham) Limited | Households | 1995 |
| Definitive Collections Limited | Other services | 2019 |
| Delderfield Bespoke Financial Services Ltd | Financial services | 2026 |
| Delta Public Health Consulting Limited | Professional & scientific | 2010 |
| Denbury Construction Ltd | Construction | 2024 |
| DEP Catering Limited | Hospitality | 2024 |
| Derfrim Limited | Professional & scientific | 2004 |
| DES RES Blinds Ltd | Wholesale & retail | 2007 |
| Design-A-Loft Limited | Construction | 2010 |
| Designage Limited | Professional & scientific | 2010 |
| Designworks Ltd | Professional & scientific | 2025 |
| Deucalion (Kent) Ltd | Real estate | 2004 |
| Deucalion Limited | Real estate | 1989 |
| Deucalion Residential Limited | Real estate | 2012 |
| Devan Office Ltd | Wholesale & retail | 2023 |
| Devcado Ltd | Information & communication | 2021 |
| Devon House Property Management Company Ltd. | Other services | 1981 |
| Dhjm Property Ltd | Real estate | 2024 |
| Diamond Aviation Training Ltd | Transport & logistics | 2016 |
| Dick Moran Consultancy Ltd | Professional & scientific | 2024 |
| Digiline Ltd | Professional & scientific | 2003 |
| Digital Gaming Solutions Limited | Administrative & support | 2024 |
| Digital Metals Ltd | Administrative & support | 2019 |
| Dillon Associates Limited | Professional & scientific | 2005 |
| Dione Technology Ltd | Information & communication | 2013 |
| Direct Services (Southern) Limited | Construction | 1992 |
| Direct Value Ltd | Financial services | 2013 |
| Distinctive Carpet & Flooring Limited | Construction | 2011 |
| DJS Mechanical Engineering Ltd | Professional & scientific | 2013 |
| DKC Accounting Ltd | Professional & scientific | 2013 |
| DLS Property Developments Ltd | Real estate | 2020 |
| DM Performance Ltd | Wholesale & retail | 2013 |
| DMS Barbers Limited | Other services | 2016 |
| Docket Technology Limited | Information & communication | 2008 |
| Dodwell Property Group Limited | Real estate | 2026 |
| Dodwells Ltd. | Construction | 2017 |
| Dogs & Co. Ltd | Wholesale & retail | 2013 |
| Dome Hill Residential Trust Limited | Real estate | 1982 |
| DON Ruffles Limited | Administrative & support | 1998 |
| Doorhawk Ltd | Wholesale & retail | 2021 |
| Dorking Vapestore Ltd | Wholesale & retail | 2018 |
| Dorli Property Group Ltd | Households | 2024 |
| Dotgo Ltd | Information & communication | 2019 |
| Double Force Technology Ltd | Professional & scientific | 2017 |
| Dovetail Foks Limited | Administrative & support | 2006 |
| Doveton Road Management Company Ltd. | Households | 2000 |
| Downey Advisory Ltd | Professional & scientific | 2023 |
| DR Elena Karnovitch Ltd | Health & social care | 2017 |
| DR Mower Limited | Other services | 2021 |
| DR Rishi Patel Ltd | Health & social care | 2015 |
| Drainrod Environmental Services Limited | Construction | 1991 |
| Drainrod Environmental Services Trading Ltd | Construction | 2019 |
| Dream Walls London Ltd | Construction | 2021 |
| DRH Auto Body Car Sales Limited | Wholesale & retail | 2015 |
| DRH Auto Body Cosmetics Limited | Wholesale & retail | 2011 |
| Drive Digital Limited | Information & communication | 2010 |
| Driver Wood Limited | Arts & recreation | 2011 |
| DRK Kitchen Renovations Ltd | Construction | 2024 |
| DS Pensions and Investments Ltd | Financial services | 2022 |
| DS Retail Ltd | Wholesale & retail | 2024 |
| DSB Diagnostic Imaging Ltd | Health & social care | 2024 |
| DSM London Ltd | Administrative & support | 2023 |
| Dtail Hair Ltd | Other services | 2014 |
| Dtension Limited | Arts & recreation | 1998 |
| Duffy Hair Limited | Other services | 2025 |
| Dulwich Health Limited | Wholesale & retail | 2001 |
| Dunvegan Properties Limited | Households | 1964 |
| Dupont Latour Ltd | Professional & scientific | 2011 |
| DVH Construction Ltd | Construction | 2020 |
| Dyce Homes Ltd | Real estate | 2024 |
| Dynamic Assist Limited | Information & communication | 2024 |
| Dyss Associates Limited | Real estate | 2018 |
| E Blue Ltd | Real estate | 2015 |
| E Expertise Limited | Administrative & support | 1997 |
| E&M Surrey Properties Limited | Real estate | 2022 |
| E-Mentoring Limited | Information & communication | 2003 |
| E.E.S. (London) Limited | Construction | 1990 |
| E.E.S. (Midlands) Limited | Extraterritorial | 1994 |
| E.Swonnell(Silverware)Limited | Wholesale & retail | 1957 |
| E1 Construction Ltd | Construction | 2022 |
| E14 Media Limited | Extraterritorial | 2009 |
| EAR ENT Health Ltd | Health & social care | 2018 |
| Earl Power Engineering Limited | Construction | 1963 |
| Easilegal Limited | Professional & scientific | 2021 |
| East Surrey Dial-A-Ride | Transport & logistics | 1999 |
| Easy Aquatics Limited | Agriculture & fishing | 2020 |
| Easylpa Limited | Professional & scientific | 2012 |
| Eaton Place (Caterham) Residents Management Company Limited | Households | 2010 |
| Eclip-Sys Holdings Ltd | Financial services | 2023 |
| Eclip-Sys Trading Ltd | Information & communication | 2023 |
| Eco Roofing South East Limited | Extraterritorial | 2020 |
| Eco-Point (UK) Ltd | Wholesale & retail | 2018 |
| Eddie & MAC Limited | Health & social care | 2014 |
| EDGE360 Limited | Hospitality | 2015 |
| Edipaws DDC Ltd | Other services | 2023 |
| Edison Networks Ltd | Information & communication | 2013 |
| Edwards Leer Engineering Services Ltd | Construction | 2025 |
| Eema Gems Ltd | Wholesale & retail | 2024 |
| Effective Pension Solutions Limited | Professional & scientific | 2000 |