| Delights Super Store Limited | Wholesale & retail | 2024 |
| Delishaj Construction Limited | Construction | 2023 |
| DELTA13 Limited | Hospitality | 2022 |
| Denick Creative Ltd | Construction | 2023 |
| Denlife Ltd | Arts & recreation | 2022 |
| Denwell Estates Ltd | Households | 2005 |
| Desai-Foot Trading Ltd | Wholesale & retail | 2024 |
| Deshield Security (London) Company Limited | Administrative & support | 2026 |
| Desilove Ltd | Wholesale & retail | 2013 |
| Dessy Beauty Ltd | Construction | 2023 |
| Destination Everywhere Ltd | Information & communication | 2024 |
| Devonshire Construction Services Ltd | Construction | 2023 |
| DFB Property Investments Ltd | Real estate | 2022 |
| Dg's Helping Hands Ltd | Construction | 2024 |
| DH Humphris UK Limited | Professional & scientific | 2016 |
| DH Landscaping Ltd | Administrative & support | 2019 |
| Dhanak London Limited | Other services | 2018 |
| DI Canris Ltd | Health & social care | 2012 |
| Diamond Home Improvements Ltd | Construction | 2024 |
| Diamond Stone Construction Limited | Construction | 2026 |
| DIAMOND1 Constructions Ltd | Construction | 2026 |
| Digi Values Limited | Real estate | 2022 |
| Digital Architectures Ltd | Information & communication | 2018 |
| Digital Props Limited | Information & communication | 2008 |
| Digitek Consultancy Ltd | Information & communication | 2018 |
| Dios TE AMA Ltd | Wholesale & retail | 2023 |
| DIP Developments Limited | Real estate | 2017 |
| Distinctlink Technology Services Ltd | Information & communication | 2025 |
| District Plumbing & Heating Ltd | Construction | 2021 |
| Divine Plumbing Limited | Construction | 2024 |
| Divinus Providentia Corporation Limited | Professional & scientific | 1997 |
| DJH Site Services Limited | Construction | 2025 |
| DLM Media Services Limited | Arts & recreation | 2023 |
| DLO Foods Limited | Financial services | 2011 |
| DLS Solutions Ltd | Construction | 2008 |
| DM & GK Ltd | Construction | 2013 |
| DM Consultancy Limited | Professional & scientific | 2019 |
| DMA Building Ltd | Construction | 2025 |
| Dn-A Trustees Limited | Professional & scientific | 2024 |
| Dngy Properties Ltd | Real estate | 2025 |
| Doco Ltd | Professional & scientific | 2022 |
| Dolphins Fish Bar Limited | Hospitality | 2022 |
| DON Nice Entertainment Limited | Information & communication | 2023 |
| Donvas Construction Ltd | Construction | 2019 |
| Doorstep Dreams Limited | Extraterritorial | 2021 |
| Dope Design Limited | Arts & recreation | 2006 |
| DOT 2 DOT Limited | Construction | 2000 |
| DOT to DOT Creative Limited | Professional & scientific | 2018 |
| Dottyline Design Ltd | Professional & scientific | 2014 |
| Downsyndrome OK | Other services | 2003 |
| DPI Digital Ltd | Information & communication | 2005 |
| DR Locum Limited | Health & social care | 2012 |
| Dragon City Stanley Ltd | Hospitality | 2024 |
| Drain Hub Ltd | Water & waste | 2024 |
| Drakes Contractor Services UK Ltd | Information & communication | 2020 |
| Draught House Ltd | Arts & recreation | 2011 |
| Dream Homes Estate Agents Limited | Real estate | 2020 |
| Dream Windows and Doors Private Limited | Construction | 2025 |
| Dreamlink Media Ltd | Professional & scientific | 2026 |
| DS General Services Ltd | Professional & scientific | 2023 |
| DSK Carpentry Ltd | Construction | 2014 |
| DT Marketing Ltd | Arts & recreation | 2018 |
| DT Plumbing, GAS & Heating Ltd | Construction | 2025 |
| DUA Beauty Ltd | Other services | 2021 |
| Dudley & Sons Ltd | Real estate | 2020 |
| Dumarc Limited | Construction | 2013 |
| Dunbridge Computing Limited | Information & communication | 1997 |
| Duthie White (Film & Television Services) Limited | Professional & scientific | 2014 |
| DVG Star Group Ltd | Administrative & support | 2019 |
| DVG Star Ltd | Information & communication | 2012 |
| DW Engineering (EN) Ltd | Wholesale & retail | 2024 |
| DW Hydrographic Ltd | Professional & scientific | 2024 |
| Dylan Parry Ltd | Professional & scientific | 2019 |
| Dynamic Code Limited | Information & communication | 2026 |
| Dynamic Workforce Limited | Information & communication | 2011 |
| Dynamique Software Limited | Information & communication | 2014 |
| E & L Mechanical Engineering Ltd | Wholesale & retail | 2022 |
| E-Shop Pro Hub Ltd | Construction | 2025 |
| EAG Properties Ltd | Real estate | 2016 |
| EAG Property Solutions Ltd | Real estate | 2011 |
| Earth Hiring Ltd | Administrative & support | 2025 |
| Eaststar Consultants Limited | Information & communication | 2003 |
| Easy FIX Roofing and Plumbing Limited | Construction | 2025 |
| Ebees Solutions Limited | Information & communication | 2014 |
| EBT Aesthetics Ltd | Health & social care | 2025 |
| EC Bookkeeping Limited | Professional & scientific | 2024 |
| Ec-London Ltd | Administrative & support | 2003 |
| EC4 Resources Ltd | Water & waste | 2024 |
| Echo Sixty One Events Ltd | Arts & recreation | 2022 |
| Eclipse INT Limited | Professional & scientific | 2017 |
| Ecolocal Lodge Development Ltd | Construction | 2016 |
| Ecolocal Services Ltd. | Professional & scientific | 2003 |
| Ecom Horizons Limited | Wholesale & retail | 2021 |
| Edgehill Properties Limited | Administrative & support | 1995 |
| EDI Painting & Decorating Ltd | Construction | 2018 |
| Eduards Investment Ltd | Wholesale & retail | 2022 |
| Education Technology Ltd | Information & communication | 2019 |
| EE Building Services Ltd | Construction | 2021 |
| Eeag Estates Ltd | Real estate | 2021 |
| Efinnos Ltd | Real estate | 2024 |