| THE Points Management Company Limited | Real estate | 2022 |
| THE Power Link Freight Ltd | Transport & logistics | 2025 |
| THE Prima Group (Carlisle) Limited | Wholesale & retail | 2010 |
| THE Real PUB Cumbria Limited | Hospitality | 2016 |
| THE Rebuild Site CIC | Wholesale & retail | 2021 |
| THE Redeemed Christian Church of GOD (Rccg) Carlisle Prayer Chapel | Other services | 2025 |
| THE Ridings (Blackwell) Flat Management Company Limited | Households | 2016 |
| THE Ridings (Blackwell) Management Company Limited | Households | 2014 |
| THE Rock - Currock Youth Project | Health & social care | 2006 |
| THE Salon (Annan) Limited | Other services | 2021 |
| THE Salon (M & N) Limited | Other services | 2002 |
| THE Sandwich Mill (Carlisle) Limited | Hospitality | 2025 |
| THE Sandwich Mill (Cumbria) Limited | Hospitality | 2011 |
| THE Science Booth Limited | Education | 2023 |
| THE Sensory Nook Limited | Hospitality | 2023 |
| THE Service Works Ltd | Extraterritorial | 2005 |
| THE Sewing Room Carlisle Ltd | Other services | 2024 |
| THE Shepherd's Arms Hotel Limited | Hospitality | 2012 |
| THE Showing Council | Agriculture & fishing | 2008 |
| THE Sidings Port Road Limited | Extraterritorial | 2012 |
| THE Silks (Galgate) Management Company Limited | Households | 2016 |
| THE Silver PUB Company Limited | Hospitality | 2002 |
| THE Skin Genie Clinic Limited | Other services | 2021 |
| THE Skin Lounge Carlisle Ltd | Other services | 2022 |
| THE Skip Network Limited | Administrative & support | 2008 |
| THE SKN Clinic Ltd | Other services | 2026 |
| THE Soft Play Collective Limited | Hospitality | 2026 |
| THE Solway Aviation Society Ltd | Arts & recreation | 1992 |
| THE Split Screen Barista Limited | Hospitality | 2021 |
| THE String of Horses Limited | Hospitality | 2007 |
| THE Superior Sewing Centre Limited | Wholesale & retail | 2006 |
| THE Sycamores (Blackburn) Management Company Limited | Real estate | 2018 |
| THE Tanning Loft Carlisle Limited | Other services | 2023 |
| THE Tavern at Hale Ltd | Hospitality | 2026 |
| THE Thorne Tree Bistro Ltd | Hospitality | 2023 |
| THE Tile & Bathroom Company Limited | Construction | 2008 |
| THE Tipsy Vegan Ltd | Hospitality | 2017 |
| THE Town Fryer Orton Road Ltd | Hospitality | 2025 |
| THE Trading Barn Ltd | Wholesale & retail | 2025 |
| THE Tranquil Otter Investments Limited | Financial services | 2010 |
| THE Tranquil Otter Limited | Hospitality | 1998 |
| THE Treasure Trinket Limited | Wholesale & retail | 2025 |
| THE Tugboat Limited | Hospitality | 2019 |
| THE Ugly Duckling Beauty Carlisle Ltd | Other services | 2022 |
| THE UK Sculpt Academy Limited | Other services | 2026 |
| THE Ultimate 10 Percent Limited | Professional & scientific | 2011 |
| THE Venue Art Centre Limited | Arts & recreation | 2019 |
| THE Waders (Blitterlees) Management Company Limited | Households | 2024 |
| THE Webstores Company (UK) Limited | Manufacturing | 2018 |
| THE Whistle Cleaning Co (Carlisle) Limited | Other services | 2005 |
| THE Willows (Darlington) Management Company Limited | Real estate | 2020 |
| THE WIN Project Limited | Health & social care | 2016 |
| THE World Made Easy Ltd | Other services | 2017 |
| THE Yellow Earl Limited | Hospitality | 2016 |
| THE Yoga Studio Carlisle (Holdings) Ltd | Arts & recreation | 2019 |
| THE Yoga Studio Carlisle Ltd | Arts & recreation | 2018 |
| THE ZEN DEN Collective CIC | Health & social care | 2026 |
| Theatre School Carlisle LLP | | 2025 |
| Thermo King Northern Limited | Manufacturing | 1987 |
| Thhp Property Ltd | Real estate | 2026 |
| Thimble Hall Leisure Pool Limited | Arts & recreation | 2018 |
| Think Tank Innovations Limited | Information & communication | 2017 |
| Thirdbox Ltd | Professional & scientific | 2023 |
| Thirlmere Investments Ltd | Financial services | 2018 |
| Thirlwell Gardens (Management) Limited | Other services | 1998 |
| Thistle Lodges Limited | Hospitality | 2001 |
| Thistle Transport Limited | Real estate | 1932 |
| Thomas Graham & Sons Limited | Wholesale & retail | 1960 |
| Thomas Graham Limited | Wholesale & retail | 2003 |
| Thomas Hammond Group Limited | Administrative & support | 2022 |
| Thomas Jardine & Company Limited | Real estate | 2019 |
| Thomas Niven Limited | Administrative & support | 1920 |
| Thomas Ross Electrical Contractor Ltd | Construction | 2018 |
| Thompson Accident Repair Centre Limited | Administrative & support | 2011 |
| Thompson Heating Limited | Construction | 2025 |
| Thompsons Plant Hire Limited | Agriculture & fishing | 1994 |
| Thompsons Services NE Ltd | Construction | 2012 |
| Thomson Roofing & Seamless Guttering Limited | Construction | 2025 |
| Thomson Trade Supplies Cumbria Limited | Other services | 2024 |
| Thornedge Management Limited | Households | 2021 |
| Thornton Court Residents Management Company Limited | Households | 2017 |
| Thorpe Content Ltd | Professional & scientific | 2021 |
| Three Hills Gelato Ltd | Wholesale & retail | 2023 |
| Thurnhams House Management Company Limited | Households | 2010 |
| Thwaite Holme Kitchens & Bedrooms Limited | Manufacturing | 2000 |
| Tictrans Ltd | Transport & logistics | 2020 |
| Tidl UK Limited | Wholesale & retail | 2024 |
| Tiffen & Co Limited | Real estate | 1991 |
| Tiffin Distribution Ltd | Transport & logistics | 2020 |
| Tiger Lake Construction Ltd | Construction | 2020 |
| Tilemasters (Cumbria) Limited | Construction | 2004 |
| TIM Wallis Limited | Professional & scientific | 2006 |
| Timber Frame North West Ltd | Construction | 2011 |
| Time Life Sofas Limited | Wholesale & retail | 2025 |
| Timmy's Bar & Kitchen Ltd | Hospitality | 2020 |
| Tingey Decorators Limited | Construction | 2025 |
| Tiny Demolition Company Ltd | Water & waste | 2022 |
| Tiny Tootsies Ltd | Health & social care | 2026 |
| TIP Top Teaching Limited | Education | 2026 |
| TIS TIS Limited Limited | Information & communication | 2025 |