| Alan Hoskins Limited | Information & communication | 2002 |
| Alan Reay Limited | Wholesale & retail | 2017 |
| Alan Tuer Limited | Construction | 1979 |
| Albion Shops Limited | Wholesale & retail | 2024 |
| Albius Group Limited | Real estate | 2018 |
| Albo Limited | Real estate | 2002 |
| Alca Holding Limited | Financial services | 2026 |
| Alcaman Ltd | Real estate | 2017 |
| Alders Edge (Scotby) Management Company Limited | Households | 2013 |
| Aleerah Ltd | Wholesale & retail | 2026 |
| Alethia Ltd | Professional & scientific | 1999 |
| Alex Clark Designs Ltd | Professional & scientific | 2023 |
| Alex Sibbald Ltd | Agriculture & fishing | 2011 |
| Alexander Shen Limited | Real estate | 2014 |
| Alexandra Court York LLP | | 2016 |
| Alexandros @ Home Limited | Hospitality | 2025 |
| Alexandros Greek Deli Limited | Wholesale & retail | 2009 |
| Alexandros Greek Restaurant Limited | Hospitality | 2005 |
| Alexcipfis Logistic Limited | Transport & logistics | 2017 |
| Alfa Cleaning Ltd | Administrative & support | 2010 |
| Alfie's Project Carlisle CIC | Education | 2024 |
| ALI Tandoori Ltd | Hospitality | 2024 |
| Alien Carlisle Limited | Hospitality | 2022 |
| Alkaid Works Ltd | Professional & scientific | 2024 |
| ALL Nation Super Store 1 Ltd | Wholesale & retail | 2025 |
| ALL Seasons Home Care (Carlisle) Limited | Health & social care | 2010 |
| ALL Things Toasty Software Ltd | Information & communication | 2024 |
| Allan Construction and Surfacing Contractors Ltd | Construction | 2026 |
| Allan Hodgson Roofing Contractor Ltd | Construction | 2018 |
| Allan Kirkbride PVC Windows & Doors Limited | Construction | 2020 |
| Allengrove Electrical Ltd | Construction | 2019 |
| Allenwood Enterprises Limited | Administrative & support | 1966 |
| Allenwood Kennels Limited | Other services | 2005 |
| Allied Technology Ltd | Information & communication | 2022 |
| Allison Farming | Agriculture & fishing | 2024 |
| Allura by Asha Limited | Wholesale & retail | 2026 |
| Almery 1954 Limited | Extraterritorial | 2013 |
| Alpha Accounts Limited | Professional & scientific | 2022 |
| Alpha-All Home Renovations Ltd | Construction | 2023 |
| Alphaville Consultants Limited | Information & communication | 2005 |
| ALS Autocare Limited | Wholesale & retail | 2017 |
| ALS Commercials Limited | Transport & logistics | 2026 |
| Alternative Facts Records Limited | Information & communication | 2020 |
| Alto Exhibitions Limited | Construction | 2002 |
| Alton Street (Carlisle) Limited | Households | 2010 |
| Altrech Limited | Manufacturing | 1993 |
| Alyina Limited | Health & social care | 2017 |
| AM World Group Limited | Households | 2025 |
| Amafa Global Academy Limited | Education | 2026 |
| Amante Bar Carlisle Ltd | Hospitality | 2023 |
| Amante Limited | Hospitality | 2018 |
| Amato's Limited | Hospitality | 2014 |
| Ambassador Accommodation Ltd | Hospitality | 2023 |
| Amberwood Cars Ltd | Wholesale & retail | 2022 |
| Amcat(Uk) Ltd | Real estate | 2013 |
| Amck Consultancy Limited | Administrative & support | 2014 |
| Amhh Holdings Ltd | Extraterritorial | 2023 |
| Amicable Care Ltd | Administrative & support | 2016 |
| Amigos Retail Limited | Wholesale & retail | 2024 |
| Ammar Group Ltd | Hospitality | 2025 |
| AMP Electrical (Carlisle) Limited | Construction | 2013 |
| Amplify Events Group Ltd | Arts & recreation | 2026 |
| AMR Car & Commercial Limited | Wholesale & retail | 2022 |
| AMT Data Solutions Ltd | Information & communication | 2018 |
| Anarchy INK Tattoo Parlour Ltd | Arts & recreation | 2024 |
| Anatolia Kebab Ltd | Hospitality | 2024 |
| Ancestors of Dover Limited | Manufacturing | 1992 |
| Andalusian Limited | Hospitality | 2010 |
| Andalusian Property Co Limited | Real estate | 2025 |
| Andana Group Limited | Construction | 2025 |
| Andersons (Denton Holme) Limited | Wholesale & retail | 1996 |
| Andessa Services Limited | Other services | 2017 |
| Andrei Gall Ltd | Transport & logistics | 2025 |
| Andrew Bates Ltd | Transport & logistics | 2025 |
| Andrew Bayliff Consulting Ltd | Professional & scientific | 2020 |
| Andrew Crabtree Haulage Limited | Transport & logistics | 2017 |
| Andrew Errington Ltd | Construction | 2025 |
| Andrew Hewitt Properties Limited | Real estate | 2026 |
| Andrew Johnston (Contracting) | Administrative & support | 2009 |
| Andrew William Carruthers Ltd | Transport & logistics | 2025 |
| Andy Francis Scooters | Wholesale & retail | 2012 |
| Andy Ross Timber Frame Ltd | Construction | 2018 |
| Aneesah's Aesthetics Ltd | Extraterritorial | 2024 |
| Angel Hair Salon Limited | Other services | 2008 |
| Angel Nails (Carlisle) Ltd | Other services | 2021 |
| Anguswell Limited | Agriculture & fishing | 2021 |
| Animax Limited | Manufacturing | 1981 |
| Anindya Gupta Limited | Health & social care | 2024 |
| Annantown Garage Ltd | Wholesale & retail | 2018 |
| Another Level Building & Maintenance Ltd | Construction | 2017 |
| Another Level Cleaning Ltd | Administrative & support | 2023 |
| Another Weigh CIC | Wholesale & retail | 2018 |
| Another Weigh Kendal Limited | Wholesale & retail | 2019 |
| Anser Ltd | Financial services | 2021 |
| Anthony Bell Ltd | Transport & logistics | 2026 |
| Anthony D. Wilson Ltd. | Professional & scientific | 2011 |
| Anthorn Social Club Ltd | Hospitality | 2021 |
| Anvil Close Management Company Limited | Households | 2025 |
| AP Holdings (Carlisle) Ltd | Hospitality | 2024 |
| Apex Fluid Power Limited | Manufacturing | 2013 |