| EWM Holdings Limited | Professional & scientific | 2001 |
| EWM Properties Limited | Professional & scientific | 2018 |
| EWM Retail Limited | Extraterritorial | 2019 |
| Excel Childcare (HD8) Ltd | Education | 2016 |
| Executive Cabs Limited | Transport & logistics | 2004 |
| Expandtreat Enterprises Limited | Other services | 1993 |
| Expertlist Limited | Information & communication | 1999 |
| Explore Holdings Ltd | Financial services | 2014 |
| Explosive Productions Limited | Administrative & support | 2004 |
| Exterior Extreme Clean Ltd | Administrative & support | 2023 |
| External Cleaning Cumbria Limited | Administrative & support | 2007 |
| Extract Engineering Limited | Professional & scientific | 2013 |
| Extraurban Property Management Limited | Households | 1989 |
| Exult Aesthetics Ltd | Health & social care | 2023 |
| Exult Cosmetics & Academy Limited | Health & social care | 2016 |
| Eziblinds Ltd | Wholesale & retail | 2009 |
| F R Construction Limited | Construction | 2014 |
| F R G W Limited | Construction | 2015 |
| F Y Path Limited | Health & social care | 2016 |
| F.B.H. Marketing Limited | Wholesale & retail | 1984 |
| Fabweld Ltd | Manufacturing | 2012 |
| Facility Solutions Management Limited | Professional & scientific | 2013 |
| Fairfields Manor (Crawcrook) Management Company Limited | Real estate | 2017 |
| Fairfields Residents Management Company Limited | Households | 2022 |
| Fairladies Management Limited | Households | 2005 |
| Fairladies Two Management Limited | Households | 2009 |
| Fairview Farming Limited | Agriculture & fishing | 2020 |
| Fairwater Capital LLP | | 2015 |
| Fairwater Capital Services Limited | Other services | 2015 |
| Falcon Motors Carlisle Ltd | Transport & logistics | 2025 |
| Falcon Veterinary Group Ltd | Professional & scientific | 2018 |
| False Peak Ltd | Wholesale & retail | 2024 |
| Family Foot Clinic Limited | Health & social care | 2009 |
| Fanbreeze Limited | Professional & scientific | 2004 |
| Fanciful Pantser Books Ltd | Information & communication | 2024 |
| Fantails (Wetheral) Limited | Hospitality | 2002 |
| FAR RC Limited | Professional & scientific | 2024 |
| Farley Consultancy (Harrogate) Ltd | Professional & scientific | 2015 |
| Farm Cottage Ltd | Households | 2025 |
| Farmello Investments Ltd | Financial services | 2024 |
| Farmhouse Cuisine Ltd | Manufacturing | 2024 |
| Farne Limited | Extraterritorial | 2018 |
| Farwood Lodge Properties Ltd | Real estate | 2025 |
| Fauld Farm Limited | Agriculture & fishing | 2010 |
| Faunus Forestry Ltd | Agriculture & fishing | 2024 |
| Fawcett Lettings Ltd | Real estate | 2023 |
| Fcsc Audit Services Limited | Professional & scientific | 2019 |
| FD Holdings Group Ltd | Financial services | 2026 |
| FDT Farms | Agriculture & fishing | 2008 |
| Fearless Feat Limited | Manufacturing | 2011 |
| Feddon Construction Limited | Construction | 2019 |
| Feedwise Limited | Wholesale & retail | 2020 |
| Feel Good Marketing Limited | Administrative & support | 2025 |
| Feeld Ltd | Information & communication | 2014 |
| Fell Holdings Ltd | Financial services | 2020 |
| Fell View Property Developments Ltd | Extraterritorial | 2021 |
| Fells & Ales Limited | Hospitality | 2017 |
| Fellside Eggs Limited | Agriculture & fishing | 2003 |
| Fellside Events Ltd | Arts & recreation | 2020 |
| Fellside Manor (Endmoor) Management Company Limited | Real estate | 2021 |
| Felltrax Ltd | Wholesale & retail | 2020 |
| Fellview Farms Limited | Agriculture & fishing | 2009 |
| Fellview Holdings Ltd | Real estate | 2026 |
| Fellwater Coffee Ltd | Hospitality | 2021 |
| Femdesigner Limited | Information & communication | 2010 |
| Ferguson Fire Door Ltd | Public administration | 2019 |
| Ferguson Technical Limited | Public administration | 2024 |
| Festaff Limited | Arts & recreation | 2012 |
| Fevara (UK) Limited | Manufacturing | 1950 |
| Fevara International Finance Limited | Financial services | 2017 |
| Fevara PLC | Professional & scientific | 1908 |
| Feveral Ltd | Administrative & support | 2025 |
| FF Associates Ltd | Professional & scientific | 2008 |
| FFG 1 Ltd | Financial services | 2021 |
| Fhem R.E.P Limited | Real estate | 2020 |
| Field & Feather Ltd | Agriculture & fishing | 2025 |
| Final Journey Funerals Limited | Extraterritorial | 2017 |
| Finch’S Welding Ltd | Wholesale & retail | 2022 |
| Fine Carpets & Flooring Ltd | Construction | 2017 |
| Fine Ceramic Transfers Limited | Extraterritorial | 1990 |
| Finesse Pvcu Limited | Construction | 1998 |
| Fircroft Wildlife Ltd | Arts & recreation | 2025 |
| Fire Cell Consultancy Ltd | Professional & scientific | 2012 |
| Fire Door 360 Limited | Construction | 2026 |
| Fire Protective Coatings (UK) Limited | Extraterritorial | 2000 |
| Firehouse Pizza Limited | Hospitality | 2025 |
| First Central Heating Company Limited | Energy | 2015 |
| First Engineering Services Ltd | Manufacturing | 2000 |
| First Friends Nursery & Pre-School C.I.C. | Education | 2017 |
| First Time Education & Recruitment Ltd | Education | 2018 |
| Firstprobe Limited | Wholesale & retail | 1986 |
| Firth Fyne Fish Ltd | Manufacturing | 2002 |
| FISH21 Limited | Professional & scientific | 2017 |
| Fisher Boyd Holdings | Financial services | 2017 |
| Fisher Property Associates Ltd | Real estate | 2026 |
| Fisher Street Properties Limited | Real estate | 2012 |
| FIT2WORK Limited | Administrative & support | 2015 |
| Five Bells Services Ltd | Manufacturing | 2024 |
| Five Feet Fit Ltd | Wholesale & retail | 2026 |
| Five Minutes Spare Ltd | Information & communication | 2012 |