| CEP Northwest Limited | Wholesale & retail | 2025 |
| Ceramic Systems (Northern) Limited | Wholesale & retail | 2009 |
| Cero Group Limited | Manufacturing | 2025 |
| Certes Limited | Administrative & support | 2004 |
| Certes Properties Limited | Administrative & support | 2018 |
| Cesr-Uk Ltd | Education | 2023 |
| Ceynac Developments Ltd | Construction | 2007 |
| CG Sansom GAS & Heating Limited | Construction | 2019 |
| CG Services Limited | Manufacturing | 2015 |
| CGM Cumbria Granite & Marble Limited | Manufacturing | 2002 |
| CGS Finance Academy Ltd | Education | 2021 |
| CGS Stores Ltd | Wholesale & retail | 2015 |
| Cgwp Holdings Limited | Financial services | 2023 |
| Chaat & Chaii Ltd | Hospitality | 2025 |
| Chalet Farm Potatoes Limited | Agriculture & fishing | 2020 |
| Chancel Place (Longhoughton) Management Company Limited | Real estate | 2018 |
| Chang YUN Ltd | Hospitality | 2026 |
| Changemate Pro Ltd | Professional & scientific | 2025 |
| Changes (Carlisle) Ltd | Health & social care | 2017 |
| Chapel Hair Ltd | Other services | 2017 |
| Chapelfield Management Limited | Real estate | 2018 |
| Chapmans (Casks & Drums) Limited | Real estate | 1950 |
| Charlie Stobbart Haulage Limited | Transport & logistics | 2026 |
| Charlotte Bendon Plastic Surgery Ltd | Health & social care | 2026 |
| Charlton Stone Supplies Limited | Professional & scientific | 2003 |
| Chatson Homes Limited | Construction | 2026 |
| Chatsworth Tennis Club Limited | Education | 2017 |
| Chaucer Logistics Limited | Transport & logistics | 2012 |
| Chauhan Foods (Derby) Ltd | Hospitality | 2020 |
| Cherry Tree Furniture Limited | Construction | 2013 |
| Cherry Tree Health Limited | Health & social care | 2022 |
| Cherry Tree Lane Management Ltd | Households | 2025 |
| Chertsey Grove Management Company Limited | Households | 2001 |
| Cheryl Nutrition and Fitness Coach Ltd | Arts & recreation | 2024 |
| Chestnut Close (Tallentire) Limited | Households | 2019 |
| Chestnut ROW Limited | Health & social care | 2023 |
| Chihen Integrated Services Ltd | Professional & scientific | 2025 |
| Childcare (Cumbria) Limited | Health & social care | 2020 |
| Chimera Veterinary Services Ltd | Professional & scientific | 2024 |
| China Express (UK) Limited | Hospitality | 2007 |
| China Palace (Carlisle) Ltd | Hospitality | 2024 |
| Chinatown (Carlisle) Ltd | Hospitality | 2025 |
| Chirton Engineering Limited | Manufacturing | 2003 |
| Chishaka Logistics Ltd | Transport & logistics | 2025 |
| Chiswick Project Controls Ltd | Professional & scientific | 2008 |
| Chiswick Street (Carlisle) Limited | Real estate | 2007 |
| Chivers Running Since 1945 Limited | Wholesale & retail | 2024 |
| Choice Furniture Direct Limited | Wholesale & retail | 2016 |
| Choice Plus Ltd. | Wholesale & retail | 2025 |
| Choice Stoves Ltd | Wholesale & retail | 2018 |
| Choose Occupational Health Limited | Health & social care | 2016 |
| Chris Building Services Limited | Construction | 2011 |
| Chris Hewitt (Plumbing & Heating) Limited | Construction | 2003 |
| Chris Nichol Construction Limited | Construction | 2000 |
| Chris Radcliffe Automotive Limited | Other services | 2018 |
| Chrisjanlaw Ltd | Health & social care | 2026 |
| Christie A.E.I. Homes Limited | Extraterritorial | 2020 |
| Church Meadows (Great Broughton) Management Company Limited | Households | 2012 |
| Chutney Château Ltd | Hospitality | 2025 |
| Chutneys Carlisle Ltd | Hospitality | 2019 |
| Ciaran Mcgivern Ltd | Professional & scientific | 2018 |
| Ciberai Ltd | Information & communication | 2024 |
| Circular 1 Consulting Limited | Professional & scientific | 2013 |
| Cirrus Consultants Ltd | Professional & scientific | 2018 |
| Cito Facilities Ltd | Other services | 2019 |
| City Cleaning and Support Services Ltd | Administrative & support | 2014 |
| City Garage Limited | Wholesale & retail | 2009 |
| City Property Maintenance Ltd | Construction | 2025 |
| City Taxis (Carlisle) Limited | Transport & logistics | 2013 |
| Civil Engineering & Construction Management Services (UK) Limited | Construction | 2018 |
| CJ Rhodes Limited | Other services | 2017 |
| CJX2 Pubs Limited | Hospitality | 2020 |
| CK Logistics Ltd | Transport & logistics | 2021 |
| CKB Cleaning and Property Clearance Ltd | Wholesale & retail | 2019 |
| CKB Site Clearance and Demolition Ltd | Construction | 2022 |
| Claims Care Advisory Limited | Professional & scientific | 2023 |
| Claims Care Consultants Ltd | Financial services | 2016 |
| Clan Royal of Scotland Limited | Extraterritorial | 1955 |
| Claremont Properties (Holdings) Limited | Financial services | 2016 |
| Claremont Properties (Newcastle) Limited | Agriculture & fishing | 1945 |
| Claremount Views Management Company Limited | Households | 2008 |
| Clark Brothers (Tipper Hire) Limited | Transport & logistics | 2007 |
| Clark Brothers Haulage Limited | Transport & logistics | 2018 |
| Clark Door Group Holdings Limited | Administrative & support | 2020 |
| Clark Mactavish Limited | Agriculture & fishing | 1999 |
| Clark Roofing Services Ltd | Construction | 2020 |
| Class Glass City UK Limited | Administrative & support | 2007 |
| Classic Robin Limited | Wholesale & retail | 2015 |
| Classique Living Limited | Wholesale & retail | 2015 |
| Claws N Paws Ltd | Wholesale & retail | 2019 |
| CLC Leisure Ltd | Hospitality | 2019 |
| Clean for Sussex Limited | Administrative & support | 2003 |
| Cleanspec Cumbria Limited | Wholesale & retail | 2014 |
| Clearview Cleaning Services (NE) Limited | Administrative & support | 2012 |
| Cleator Mills Business Park Ltd | Real estate | 2019 |
| Clever Mapping Ltd | Other services | 2014 |
| Click Retail Group Limited | Wholesale & retail | 2021 |
| Clifford Mechanical Ltd | Wholesale & retail | 2026 |
| Clift Hill 1915 Limited | Hospitality | 2019 |
| Clifton Hill Management Limited | Households | 2013 |