| Sense Production Ltd | Information & communication | 2023 |
| Sense Tourism Limited | Information & communication | 2016 |
| Senses Gallery Ltd | Wholesale & retail | 2023 |
| Senshine Ltd | Information & communication | 2023 |
| Sensibilia Limited | Wholesale & retail | 2018 |
| Sensible Driving Limited | Wholesale & retail | 2017 |
| Sensory Education Ltd | Wholesale & retail | 2024 |
| Sensory Stepping Stones Ltd | Education | 2025 |
| Sensory Wellbeing OT Ltd | Education | 2026 |
| Sensum Group Limited | Administrative & support | 2016 |
| Senteurzen Limited | Wholesale & retail | 2025 |
| Sentier Hire Ltd | Administrative & support | 2021 |
| Sentile Limited | Construction | 2019 |
| Sentinel 123 Limited | Financial services | 2023 |
| Sentinel 456 Limited | Financial services | 2023 |
| Sentinel 789 Limited | Financial services | 2023 |
| Sentinel Executive Group Ltd | Information & communication | 2025 |
| Sentinel L1 Security Limited | Financial services | 2025 |
| Sentinel Risk Ltd | Administrative & support | 2024 |
| Sentry South East Ltd | Construction | 2018 |
| SEO NOC (.PVT) Limited | Information & communication | 2021 |
| Seoclerk Ltd | Information & communication | 2021 |
| Seoulful K-Dawg Events Ltd | Hospitality | 2025 |
| Seovison Ltd | Information & communication | 2025 |
| Septa FX Global Limited | Financial services | 2021 |
| September Blues Ventures Ltd | Professional & scientific | 2023 |
| Sepvest Security Limited | Administrative & support | 2024 |
| Sequence Recruits Ltd | Administrative & support | 2018 |
| Sequence SEO Ltd | Professional & scientific | 2023 |
| Sequin Restaurants Ltd | Hospitality | 2024 |
| Sequoia Storm Ltd | Information & communication | 2021 |
| SER Benefits Ltd | Administrative & support | 2022 |
| SER Concepts Ltd | Wholesale & retail | 2026 |
| SER Consultants Ltd | Professional & scientific | 2020 |
| Sera Cracroft Limited | Arts & recreation | 2004 |
| Sera Financial Ltd | Financial services | 2024 |
| Seraco Supply Ltd | Wholesale & retail | 2025 |
| Seral Ltd | Wholesale & retail | 2024 |
| Seramix Ltd | Wholesale & retail | 2024 |
| Seraph Developments Limited | Real estate | 2015 |
| Seraph Estates (Cardiff) Ltd | Real estate | 2011 |
| Seraph Freeholdings Limited | Real estate | 2006 |
| Seraph Holdings Limited | Financial services | 2007 |
| Seraph Leaseholdings Limited | Real estate | 2006 |
| Seraphim Pictures Ltd | Information & communication | 2012 |
| Seravelle Ltd | Wholesale & retail | 2025 |
| Serbanescu Services Ltd | Transport & logistics | 2017 |
| Serbella Limited | Other services | 2013 |
| Sercet Sylk Ltd | Wholesale & retail | 2025 |
| Sercnlac Trading Co., Ltd | Extraterritorial | 2020 |
| Serdartoraman Ltd | Other services | 2024 |
| Sere Solu Ltd | Wholesale & retail | 2025 |
| Seren 2024 Ltd | Hospitality | 2024 |
| Seren AUR Ltd | Real estate | 2013 |
| Seren Court Management Company Limited | Real estate | 2007 |
| Seren Distributed Photovoltaic Technologies Limited | Professional & scientific | 2026 |
| Seren Glas Properties Limited | Real estate | 2020 |
| Seren HMU Limited | Other services | 2022 |
| Seren in Support Ltd | Health & social care | 2025 |
| Seren Investigative Training Ltd | Education | 2011 |
| Seren Legal Practice Ltd | Professional & scientific | 2021 |
| Seren Nights Twilight Hotel C.I.C. | Health & social care | 2025 |
| Seren QP Services Ltd | Real estate | 2021 |
| Seren Rentals Ltd | Real estate | 2023 |
| Seren Steps Care CIC | Health & social care | 2025 |
| Serendib AI Ltd | Wholesale & retail | 2025 |
| Serendipia Investments Ltd | Financial services | 2024 |
| Serendipity BCT Ltd | Other services | 2021 |
| Serendipité Ltd | Professional & scientific | 2020 |
| Serendity Limited | Wholesale & retail | 2025 |
| Serene Lighting Limited | Other services | 2016 |
| Serene Stays 24 Ltd | Real estate | 2024 |
| Serenia Refinishing Limited | Transport & logistics | 2018 |
| Serenity Box Co Limited | Wholesale & retail | 2019 |
| Serenity Care Home Services Ltd | Health & social care | 2026 |
| Serenity HUE Limited | Wholesale & retail | 2020 |
| Serenity LDN Ltd | Administrative & support | 2020 |
| Serenity Stairlifts Limited | Construction | 2024 |
| Sereno Digital Store Ltd | Information & communication | 2025 |
| Sergiu Ltd | Other services | 2017 |
| Sergiu Service Truck Ltd | Transport & logistics | 2025 |
| Serhat Ogur Ltd | Wholesale & retail | 2025 |
| Serica UK Ltd | Professional & scientific | 2022 |
| Serious Game Worx Limited | Construction | 2026 |
| Seriously Scented Ltd | Manufacturing | 2012 |
| Serj&Logistics Ltd | Transport & logistics | 2018 |
| Sero BEE Limited | Professional & scientific | 2023 |
| Sero Energy Limited | Financial services | 2020 |
| Sero Homes Limited | Professional & scientific | 2017 |
| Sero Life Limited | Professional & scientific | 2020 |
| Sero Technologies Limited | Professional & scientific | 2017 |
| Sertex Investments Limited | Professional & scientific | 2018 |
| Servercim Digital Services Ltd | Information & communication | 2025 |
| Servet Burak Erturan Ltd | Wholesale & retail | 2025 |
| Servica Limited | Professional & scientific | 1998 |
| Service & Consulting Ltd | Administrative & support | 2016 |
| Service Agility Limited | Information & communication | 2013 |
| Service Center Ltd | Other services | 2020 |
| Service Central Ltd | Administrative & support | 2018 |
| Service Deluxe Co Limited | Other services | 2018 |