| Erkan AYD Limited | Wholesale & retail | 2025 |
| Erkar Elektronics Ltd | Wholesale & retail | 2025 |
| Ermaagain Limited | Information & communication | 2025 |
| Ermine Trading Company Limited | Wholesale & retail | 2008 |
| ERNESTO87 Ltd | Real estate | 2024 |
| Erontec Global Limited | Other services | 2018 |
| Eros Network Limited | Information & communication | 2000 |
| ERP Apps + AI Collaborations Limited | Information & communication | 2022 |
| Erraji Capital Limited | Financial services | 2017 |
| Errigal Plant Exports Ltd | Wholesale & retail | 2020 |
| Ersan Group Limited | Wholesale & retail | 2025 |
| Ersupply Ltd | Wholesale & retail | 2026 |
| Eryr Glas Ltd | Professional & scientific | 2011 |
| ES Future Teknoloji Ticaret Ltd | Manufacturing | 2025 |
| ES Kitchen Ltd | Manufacturing | 2025 |
| ES Travel Technology Services Ltd | Information & communication | 2020 |
| ES Williams Ltd | Wholesale & retail | 2014 |
| ES1 Limited | Construction | 2019 |
| ESA Systems Limited | Professional & scientific | 2012 |
| Esabahat Ltd | Real estate | 2008 |
| Esar Investments Limited | Extraterritorial | 1951 |
| Esbee Limited | Health & social care | 2021 |
| ESC International Ltd. | Other services | 2016 |
| Esca Skin Ltd | Wholesale & retail | 2023 |
| Escape Asylum Ltd | Education | 2015 |
| Escape on Scene Ltd | Arts & recreation | 2022 |
| Escape Property Ltd | Real estate | 2020 |
| Escape Rooms Cardiff Ltd | Arts & recreation | 2015 |
| Escapes Travel Group Ltd | Administrative & support | 2019 |
| Escara Skincare Ltd | Wholesale & retail | 2024 |
| Esco Services Ltd | Administrative & support | 2018 |
| Escrip Solutions Ltd | Professional & scientific | 2021 |
| ESE Systems Ltd | Administrative & support | 2013 |
| Eseeworld Technology Limited | Wholesale & retail | 2022 |
| Esellzone Limited | Wholesale & retail | 2024 |
| Esenm Ltd | Wholesale & retail | 2023 |
| Eserify Ltd | Wholesale & retail | 2025 |
| Esetech IT Consultancy Limited | Information & communication | 2020 |
| ESG Leasing Limited | Real estate | 2026 |
| ESG Service Providers UK Ltd | Professional & scientific | 2025 |
| Esgair Galed Energy Park Limited | Energy | 2021 |
| Esgair Holdings Ltd | Financial services | 2026 |
| Esgcqups Mart Ltd | Wholesale & retail | 2025 |
| Esha Limited | Hospitality | 1998 |
| Esho Promotions Global Limited | Information & communication | 2019 |
| ESI & Sons Limited | Hospitality | 2024 |
| Eskills Limited | Education | 2016 |
| Eskimo Media and Technology Limited | Information & communication | 2016 |
| Eslamayman Ltd | Professional & scientific | 2025 |
| Eslay Ltd | Wholesale & retail | 2025 |
| ESM IT Solution Ltd | Information & communication | 2018 |
| ESN Greenline Global Trade and Investment Ltd | Wholesale & retail | 2023 |
| Esoftsetup Ltd | Wholesale & retail | 2025 |
| Esolution INT Limited | Information & communication | 2021 |
| Esoterika Limited | Wholesale & retail | 2025 |
| Espana Cars Limited | Other services | 2006 |
| Espavas Ltd | Wholesale & retail | 2022 |
| Especially IT Ltd | Information & communication | 2011 |
| Especos Trading Ltd | Construction | 2020 |
| Esper Traders Ltd | Information & communication | 2026 |
| Esperia Limited | Health & social care | 2015 |
| Esplanade Management (Porthcawl) Limited | Households | 2003 |
| Esplanade Property Company,Limited(The) | Real estate | 1927 |
| Espoc Consulting Limited | Information & communication | 2017 |
| Espy Limited | Transport & logistics | 1998 |
| Esra Dems Limited | Information & communication | 2015 |
| Esrg Property Developments PLC | Real estate | 2017 |
| Essa Group Limited | Real estate | 2018 |
| Essen Associates Ltd | Health & social care | 2013 |
| Essenciaal Ltd | Wholesale & retail | 2016 |
| Essentalvibes Ltd | Wholesale & retail | 2021 |
| Essential Bullion Limited | Wholesale & retail | 2020 |
| Essential Couture Limited | Other services | 2015 |
| Essentials Picks Ltd | Wholesale & retail | 2025 |
| Essenzi Media Ltd | Professional & scientific | 2024 |
| Essex Motors Wickford Ltd | Wholesale & retail | 2020 |
| Essex Motorz Ltd | Wholesale & retail | 2023 |
| Essex Plumbing & Heating Services Limited | Construction | 1997 |
| Essex Plumbing & Heating Solutions Limited | Construction | 2013 |
| Essex Scaffolding Hire Limited | Construction | 2026 |
| Essk Design Consultants Limited | Professional & scientific | 2006 |
| Essoens Ltd | Information & communication | 2024 |
| Essu Group Limited | Professional & scientific | 2020 |
| EST Accountants Ltd. | Professional & scientific | 2012 |
| EST CF Ltd | Financial services | 2016 |
| EST Group Ltd | Financial services | 2017 |
| EST HR Ltd | Administrative & support | 2015 |
| EST Wealth Ltd | Professional & scientific | 2019 |
| Estate Agency Group Ltd | Extraterritorial | 2020 |
| Estate and Land Holdings 2 Limited | Real estate | 2023 |
| ESTATEHOLDINGS12 Ltd | Real estate | 2021 |
| ESTATEHOLDINGS73 Ltd | Real estate | 2021 |
| Estates for Education Limited | Real estate | 2012 |
| Esteemed Cars & Valeting Ltd | Wholesale & retail | 2020 |
| Estesben Ltd | Information & communication | 2025 |
| Estetica Atelier Ltd | Other services | 2022 |
| Esther's Spa Company Ltd | Health & social care | 2017 |
| Esthete Studio Limited | Arts & recreation | 2025 |
| Estnet Ltd | Other services | 2000 |
| Estore Traders Ltd | Wholesale & retail | 2025 |