| Coach House Joinery Ltd | Construction | 2001 |
| Coaching Alliance Ltd | Professional & scientific | 2019 |
| Coaching by SB Limited | Education | 2022 |
| Coal and Bowl Ltd | Hospitality | 2026 |
| Coalcity Solutions Limited | Information & communication | 2025 |
| Coastal Surf Limited | Wholesale & retail | 2016 |
| Coates Electronics Limited | Manufacturing | 2023 |
| Cobgate (Whaplode) Management Company Limited | Households | 2023 |
| Cobit Foundation Ltd | Extraterritorial | 2025 |
| Cobnut (Hatfield) Management Limited | Households | 2023 |
| Cobwebs Furniture Ltd. | Wholesale & retail | 2007 |
| Cockbain Events Ltd | Arts & recreation | 2013 |
| Coco Property Holdings Ltd | Real estate | 2020 |
| Cocoda Limited | Professional & scientific | 2006 |
| Cocoloco Express Ltd | Health & social care | 2026 |
| Coddiwomple Ltd | Other services | 2025 |
| Code Confidence Ltd | Information & communication | 2009 |
| Code Generation Ltd | Information & communication | 2018 |
| Code Grazer Ltd | Information & communication | 2018 |
| Code Hound Ltd | Information & communication | 2018 |
| Code SA Limited | Information & communication | 2024 |
| Codedbeans Ltd | Professional & scientific | 2020 |
| Codellama Ltd | Information & communication | 2021 |
| Codemagnet Limited | Information & communication | 2016 |
| Codementor Nexus Ltd | Information & communication | 2023 |
| Coderedsecure Limited | Information & communication | 2022 |
| Codesit Limited | Information & communication | 2026 |
| Codex Felis Ltd | Information & communication | 2021 |
| Codex Technology Ltd | Manufacturing | 2025 |
| Codigm Limited | Professional & scientific | 2023 |
| Codon Communications Ltd | Professional & scientific | 2023 |
| Coed Ithel Fisheries Limited | Arts & recreation | 1966 |
| Coel Asset Management Limited | Financial services | 2019 |
| Coel Commercial Investments Ltd | Real estate | 2019 |
| Coel Group Limited | Administrative & support | 2018 |
| Coelrind Ltd | Professional & scientific | 2013 |
| Coen International Attestation Limited | Wholesale & retail | 2025 |
| Coenzyme Capital Ltd | Information & communication | 2023 |
| Coenzyme Ltd | Information & communication | 2023 |
| Cofarm Cambridge | Agriculture & fishing | 2019 |
| Cofarm Estate Limited | Information & communication | 2019 |
| Cofarm Foundation | Information & communication | 2019 |
| Coffee & Cuddles Ltd | Health & social care | 2026 |
| Coffee Bean Lettings Limited | Real estate | 2016 |
| Coffee Temple Limited | Manufacturing | 2017 |
| Coffee World (UK) Ltd | Manufacturing | 2014 |
| Cofinitive Ltd | Professional & scientific | 2014 |
| Cogitars UK Ltd | Information & communication | 2022 |
| Cogknox Limited | Manufacturing | 2025 |
| Cognics Ltd | Professional & scientific | 2023 |
| Cognidox Limited | Information & communication | 2008 |
| Cognisant Construction Limited | Construction | 2024 |
| Cognition KIT Limited | Information & communication | 2016 |
| Cognition Partners Employee Trustee Limited | Other services | 2022 |
| Cognition Partners Limited | Information & communication | 2019 |
| Cognitive Humanity Ltd | Professional & scientific | 2025 |
| Cognival Ltd | Wholesale & retail | 2025 |
| Coherence Engine Ltd | Professional & scientific | 2025 |
| Coherence Neuro Ltd | Manufacturing | 2022 |
| Coinda Ltd | Information & communication | 2025 |
| Coinfrenzy Ltd. | Information & communication | 2025 |
| Coinz Limited | Financial services | 2009 |
| Cojocaru Aero Ltd | Manufacturing | 2024 |
| Cokenach Cricket Management Services Limited | Hospitality | 2010 |
| Cokidynamics Limited | Real estate | 2025 |
| Coldchain Bars Ltd | Wholesale & retail | 2020 |
| Coldhams Place (Cambridge) Management Company Limited | Households | 2020 |
| Cole Investment Group Limited | Real estate | 2026 |
| Coleman Plant Nutrition Management (Netherlands) Co., Ltd | Wholesale & retail | 2023 |
| Coles Accounting (Cambridge) Limited | Professional & scientific | 2015 |
| Coles Scaffolding Limited | Construction | 2003 |
| Colhan Limited | Professional & scientific | 2026 |
| Colin Barnes Building Services Ltd | Construction | 2013 |
| Colin Barton Associates Limited | Professional & scientific | 2009 |
| Colin O'Dell Limited | Construction | 2010 |
| Colin Warnock Associates Limited | Professional & scientific | 2023 |
| Colittle Lanterns Limited | Information & communication | 2024 |
| Collabora Limited | Information & communication | 2005 |
| Collabora Productivity Limited | Information & communication | 2013 |
| Collaboration for Interdisciplinary Sustainable Soils Project (Ciss Project) CIC | Professional & scientific | 2024 |
| Colleenmclaughlin.Co.Uk Limited | Professional & scientific | 2021 |
| College Court (Cambridge a) Limited | Real estate | 1984 |
| College Court (Cambridge B) Limited | Real estate | 1984 |
| College Green Holdings Limited | Real estate | 2017 |
| Collegepre Education Limited | Professional & scientific | 2014 |
| Colleges Storage Solutions Ltd | Transport & logistics | 2010 |
| Collegiate Travels Ltd | Transport & logistics | 2026 |
| Collins Walker Limited | Manufacturing | 1972 |
| Collinwood Construction Ltd. | Construction | 2015 |
| Collusion Cambridge Limited | Arts & recreation | 2014 |
| Colm Joseph Gardens Limited | Professional & scientific | 2019 |
| Colne Maisonettes Limited | Households | 1975 |
| Colne Valley Railway Company Limited | Transport & logistics | 1974 |
| Cologne Road NO 24 Limited | Other services | 2005 |
| Colokate LLP | | 2013 |
| Colophon Limited | Hospitality | 1993 |
| Colorwheel International Co., Ltd | Wholesale & retail | 2024 |
| Colour Isle Limited | Professional & scientific | 2021 |
| Columbus Assets Ltd | Real estate | 2016 |
| Coman-Ri Ltd | Manufacturing | 2024 |